• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 8 ways to get from Boston to Knoxville by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Boston  •  5 h 49 min

  1. Fly from Boston (BOS) to Knoxville (TYS) BOS - TYS

$217 - $776

Cheapest option

Bus Wanda Coach  •  33 h 53 min

  1. Take the bus from Boston, MA to New York, NY
  2. Take the bus from New York, NY to Knoxville Nyc

$77

6 alternative options

Train to Providence, fly  •  6 h 58 min

  1. Take the train from Boston South Station to Providence Amtrak
  2. Fly from Providence (PVD) to Knoxville (TYS) PVD - TYS

$281 - $1,086

Train, bus NYTN Bus  •  17 h 25 min

  1. Take the train from Boston South Station to New York Penn Station Acela Express / ...
  2. Take the bus from New York, NY to Knoxville, TN

$201 - $379

Bus NYTN Bus  •  18 h 31 min

  1. Take the bus from Boston, MA to New York Boston
  2. Take the bus from New York, NY to Knoxville, TN

$139 - $242

Train Amtrak Northeast Regional, bus  •  23 h 45 min

  1. Take the train from Boston South Station to Lynchburg Amtrak
  2. Take the train from Lynchburg Amtrak to Greensboro Galyon Transportation Center
  3. Take the bus from Greensboro, Nc to Winston Salem, Nc
  4. Take the bus from Winston Salem, Nc to Knoxville, Tn

$189 - $412

Train, bus Wanda Coach  •  31 h 34 min

  1. Take the train from Boston South Station to New York Penn Station Acela Express / ...
  2. Take the bus from New York, NY to Knoxville Nyc

$142 - $216

Drive  •  15 h 39 min

  1. Drive from Boston to Knoxville 925.9 miles

$90 - $140

Questions & Answers

The cheapest way to get from Boston to Knoxville is to bus which costs $77 and takes 33 h 53 min.

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The quickest way to get from Boston to Knoxville is to fly which costs $210 - $800 and takes 5 h 49 min.

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The distance between Boston and Knoxville is 822 miles. The road distance is 925.9 miles.

Get driving directions

The best way to get from Boston to Knoxville without a car is to train and bus which takes 17 h 25 min and costs $200 - $380.

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It takes approximately 5 h 49 min to get from Boston to Knoxville, including transfers.

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The best way to get from Boston to Knoxville is to fly which takes 5 h 49 min and costs $210 - $800. Alternatively, you can bus, which costs $130 - $250 and takes 18 h 31 min.

Mode details

There is no direct flight from Boston Airport to Knoxville Airport. The quickest flight takes 4 h 12 min and has one stopover.

Search flights

Yes, the driving distance between Boston to Knoxville is 926 miles. It takes approximately 15 h 39 min to drive from Boston to Knoxville.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Boston Airport to Knoxville Airport.

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There are 104+ hotels available in Knoxville. Prices start at $54 USD per night.

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Map of how to get from Boston to Knoxville.
Launch map view
  • Distance: 822 miles
  • Duration: 5 h 49 min

What companies run services between Boston, MA, USA and Knoxville, TN, USA?

United Airlines, American Airlines and Delta fly from Boston to Knoxville hourly. Alternatively, you can take a bus from Boston to Knoxville via New York, New York, NY, Knoxville, TN, and Kingston Pike EB Mid-block just past Walker Springs in around 18 h 31 min.

Airlines
Delta
Website
delta.com
Flights from Boston to Knoxville via Detroit
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$420 - $1,800
Flights from Boston to Knoxville via Atlanta
Ave. Duration
5 h 1 min
When
Every day
Estimated price
$420 - $1,800
Flights from Boston to Knoxville via New York La Guardia
Ave. Duration
5 h
When
Monday, Tuesday, Wednesday, Friday, Saturday and Sunday
Estimated price
$420 - $1,800
Flights from Providence to Knoxville via Atlanta
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$220 - $1,100
Flights from Providence to Knoxville via Detroit
Ave. Duration
5 h 39 min
When
Every day
Estimated price
$220 - $1,100
American Airlines
Website
aa.com
Flights from Boston to Knoxville via Reagan Washington
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$410 - $1,400
Flights from Boston to Knoxville via Charlotte
Ave. Duration
4 h 48 min
When
Every day
Estimated price
$410 - $1,400
Flights from Boston to Knoxville via Philadelphia
Ave. Duration
4 h 52 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$410 - $1,400
Flights from Providence to Knoxville via Charlotte
Ave. Duration
4 h 58 min
When
Every day
Estimated price
$220 - $1,000
Flights from Providence to Knoxville via Reagan Washington
Ave. Duration
4 h 54 min
When
Monday to Saturday
Estimated price
$210 - $1,000
Flights from Providence to Knoxville via Philadelphia
Ave. Duration
5 h 33 min
When
Every day
Estimated price
$210 - $1,000
United Airlines
Website
united.com
Flights from Boston to Knoxville via Washington Dulles
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$320 - $1,400
Flights from Boston to Knoxville via Newark
Ave. Duration
4 h 37 min
When
Monday, Tuesday, Wednesday and Saturday
Estimated price
$320 - $1,400
Flights from Providence to Knoxville via Washington Dulles
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$220 - $1,100
Flights from Providence to Knoxville via Newark
Ave. Duration
5 h 17 min
When
Monday to Friday
Estimated price
$220 - $1,100
Flights from Providence to Knoxville via Chicago O'Hare
Ave. Duration
7 h 32 min
When
Every day
Estimated price
$260 - $1,200
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Boston South Station to Providence Amtrak
Ave. Duration
36 min
Frequency
Hourly
Estimated price
$14
Website
amtrak.com
Coach
$14
Business Class
$29 - $60
First Class
$65 - $95
Train from Boston South Station to New York Penn Station
Ave. Duration
3 h 42 min
Frequency
Hourly
Estimated price
$75 - $160
Website
amtrak.com
Coach
$75 - $160
Business Class
$110 - $200
First Class
$291
MBTA
Phone
617-222-3200
Website
mbta.com
Train from South Station to Providence
Ave. Duration
1 h 10 min
Frequency
Hourly
Estimated price
$14
Website
MBTA
Coach
$14
Business Class
$29 - $60
First Class
$65 - $95
Amtrak Northeast Regional
Rome2rio's guide to Amtrak Northeast Regional
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Boston South Station to Lynchburg Amtrak
Ave. Duration
12 h 21 min
Frequency
5 times a week
Estimated price
$120 - $250
Website
amtrak.com
Coach Seat
$120 - $190
Business Seat
$190 - $250
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Lynchburg Amtrak to Greensboro Galyon Transportation Center
Ave. Duration
2 h 9 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Bus operators
NYTN Bus
Website
nytnbus.com
Bus from New York, NY to Knoxville, TN
Ave. Duration
11 h 30 min
Frequency
Once daily
Estimated price
$100 - $200
Schedules at
nytnbus.com
Lucky Star Bus
Phone
(888) 881-0887 / (617) 269-5468
Email
info@luckystarbus.com
Website
luckystarbus.com
Bus from Boston, MA to New York
Ave. Duration
5 h
Frequency
Every 2 hours
Estimated price
$25
Schedules at
luckystarbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45 min
Frequency
4 times a day
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Bus from Winston Salem, Nc to Knoxville, Tn
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$30 - $75
Website
greyhound.com
Economy
$30 - $50
Flexible
$55 - $75
Sunway Charters
Phone
+1 704-348-1200
Email
info@sunwaycharters.com
Website
sunwaycharters.com
Bus from Greensboro, Nc to Winston-Salem
Ave. Duration
40 min
Frequency
Twice daily
Schedules at
sunwaycharters.com
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY to Knoxville
Ave. Duration
25 h 30 min
Frequency
6 times a week
Estimated price
$60
Schedules at
wandacoach.com
Coach Run
Website
coachrun.com
Bus from Boston, MA to New York, NY
Ave. Duration
5 h
Frequency
5 times a day
Estimated price
$12
Schedules at
coachrun.com
Book at
gotobus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The best way to get from Boston to Boston Airport is to bus which takes 11 min and costs $2 - $6.

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