There are 8 ways to get from Boston to Knoxville by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Boston  •  5 h 44 min

  1. Fly from Boston (BOS) to Knoxville (TYS) BOS - TYS

$217 - $790

Cheapest option

Bus Wanda Coach  •  33 h 52 min

  1. Take the bus from Boston, MA to New York, NY
  2. Take the bus from New York, NY to Knoxville Nyc

$77

6 alternative options

Train to Providence, fly  •  6 h 57 min

  1. Take the train from Boston South Station Amtrak to Providence Amtrak
  2. Fly from Providence (PVD) to Knoxville (TYS) PVD - TYS

$328 - $1,230

Train, bus NYTN Bus  •  17 h 29 min

  1. Take the train from Boston South Station Amtrak to New York Penn Station Acela Express / ...
  2. Take the bus from New York, NY to Knoxville, TN

$253 - $568

Bus NYTN Bus  •  18 h 1 min

  1. Take the bus from Boston, MA to New York Boston
  2. Take the bus from New York, NY to Knoxville, TN

$139 - $242

Train, bus via Greensboro Galyon Transportation Center Amtrak  •  23 h 6 min

  1. Take the train from Boston South Station Amtrak to New York Penn Station
  2. Take the train from New York Penn Station to Greensboro Galyon Transportation Center Amtrak
  3. Take the bus from Greensboro, Nc to Winston Salem, Nc
  4. Take the bus from Winston Salem, Nc to Asheville, Nc
  5. Take the bus from Asheville, Nc to Knoxville, Tn

$250 - $660

Train Amtrak Northeast Regional, bus  •  23 h 20 min

  1. Take the train from Boston South Station Amtrak to Lynchburg Amtrak
  2. Take the train from Lynchburg Amtrak to Greensboro Galyon Transportation Center Amtrak
  3. Take the bus from Greensboro, Nc to Knoxville, Tn

$180 - $397

Drive  •  15 h 39 min

  1. Drive from Boston to Knoxville 925.9 miles

$90 - $140

Questions & Answers

The cheapest way to get from Boston to Knoxville is to bus which costs $77 and takes 33 h 52 min.

More details

The quickest way to get from Boston to Knoxville is to fly which costs $210 - $800 and takes 5 h 44 min.

More details

The distance between Boston and Knoxville is 822 miles. The road distance is 925.9 miles.

Get driving directions

It takes approximately 5 h 44 min to get from Boston to Knoxville, including transfers.

More details

Map of how to get from Boston to Knoxville.
Launch map view
  • Distance: 822 miles
  • Duration: 5 h 44 min

What companies run services between Boston, MA, USA and Knoxville, TN, USA?

United Airlines, American Airlines and Delta fly from Boston to Knoxville hourly. Alternatively, you can take a bus from Boston to Knoxville via New York, New York, NY, Knoxville, TN, and Kingston Pike EB Mid-block just past Walker Springs in around 18 h 1 min.

Airlines
American Airlines
Website
aa.com
Flights from Boston to Knoxville via Philadelphia
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$410 - $1,400
Flights from Boston to Knoxville via Reagan Washington
Ave. Duration
4 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$410 - $1,400
Flights from Boston to Knoxville via Charlotte
Ave. Duration
4 h 37 min
When
Every day
Estimated price
$410 - $1,400
Flights from Providence to Knoxville via Charlotte
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$220 - $1,000
Flights from Providence to Knoxville via Reagan Washington
Ave. Duration
4 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Providence to Knoxville via Philadelphia
Ave. Duration
5 h 9 min
When
Every day
Estimated price
$210 - $1,000
Flights from Providence to Knoxville via Chicago O'Hare
Ave. Duration
7 h 50 min
When
Every day
Estimated price
$250 - $1,100
Delta
Website
delta.com
Flights from Boston to Knoxville via Detroit
Ave. Duration
4 h 41 min
When
Every day
Estimated price
$420 - $1,800
Flights from Boston to Knoxville via New York La Guardia
Ave. Duration
4 h 40 min
When
Sunday
Estimated price
$420 - $1,800
Flights from Boston to Knoxville via Atlanta
Ave. Duration
4 h 49 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$420 - $1,800
Flights from Providence to Knoxville via Detroit
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$220 - $1,100
Flights from Providence to Knoxville via Atlanta
Ave. Duration
5 h 2 min
When
Every day
Estimated price
$220 - $1,100
United Airlines
Website
united.com
Flights from Boston to Knoxville via Washington Dulles
Ave. Duration
4 h 17 min
When
Monday to Saturday
Estimated price
$320 - $1,400
Flights from Boston to Knoxville via Newark
Ave. Duration
4 h 29 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$320 - $1,400
Flights from Providence to Knoxville via Washington Dulles
Ave. Duration
5 h 41 min
When
Every day
Estimated price
$220 - $1,100
Flights from Providence to Knoxville via Newark
Ave. Duration
6 h 19 min
When
Every day
Estimated price
$220 - $1,100
Flights from Providence to Knoxville via Chicago O'Hare
Ave. Duration
5 h 29 min
When
Monday to Friday
Estimated price
$260 - $1,200
Train operators
Amtrak Acela Express
Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Boston South Station Amtrak to Providence Amtrak
Ave. Duration
34 min
Frequency
Hourly
Estimated price
$60 - $160
Website
amtrak.com
Business Seat
$60 - $150
First Class Seat
$120 - $160
Train from Boston South Station Amtrak to New York Penn Station
Ave. Duration
3 h 46 min
Frequency
Every 3 hours
Estimated price
$120 - $340
Website
amtrak.com
Business Seat
$120 - $260
First Class Seat
$220 - $340
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
10 h
Frequency
Twice daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$130 - $200
Business Coach Seat
$150 - $210
Room
$320 - $450
Train from Lynchburg Amtrak to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
2 h 9 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Amtrak Northeast Regional
Rome2rio's guide to Amtrak Northeast Regional
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Boston South Station Amtrak to Lynchburg Amtrak
Ave. Duration
12 h 26 min
Frequency
5 times a week
Estimated price
$120 - $250
Website
amtrak.com
Coach Seat
$120 - $190
Business Seat
$190 - $250
Bus operators
NYTN Bus
Website
nytnbus.com
Bus from New York, NY to Knoxville, TN
Ave. Duration
11 h 30 min
Frequency
Once daily
Estimated price
$100 - $200
Schedules at
nytnbus.com
Lucky Star Bus
Phone
(888) 881-0887 / (617) 269-5468
Email
info@luckystarbus.com
Website
luckystarbus.com
Bus from Boston, MA to New York
Ave. Duration
4 h 30 min
Frequency
Every 2 hours
Estimated price
$25
Schedules at
luckystarbus.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Asheville, Nc to Knoxville, Tn
Ave. Duration
2 h 20 min
Frequency
Every 2 hours
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40
Bus from Greensboro, Nc to Knoxville, Tn
Ave. Duration
6 h 45 min
Frequency
Every 2 hours
Estimated price
$30 - $80
Website
greyhound.com
Economy
$30 - $55
Flexible
$60 - $80
Coach Run
Website
coachrun.com
Bus from Boston, MA to New York, NY
Ave. Duration
5 h
Frequency
5 times a day
Estimated price
$12
Schedules at
coachrun.com
Book at
gotobus.com
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY to Knoxville
Ave. Duration
25 h 30 min
Frequency
6 times a week
Estimated price
$60
Schedules at
wandacoach.com

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