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There are 5 ways to get from Boston to Florence by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  5h 26m

  1. Fly from Boston (BOS) to Florence (FLO) BOS - FLO

$210 - $1,121

Cheapest option

Bus  •  16h

  1. Take the bus from Boston South Buses to New York Boston
  2. Take the bus from New York, NY to Florence, SC Nyc

$70 - $95

3 alternative options

Train  •  16h 19m

  1. Take the train from Boston South Station to New York Penn Station Acela / ...
  2. Take the train from New York Penn Station to Florence Amtrak Station Palmetto / ...

$109 - $227

Bus via New York  •  17h 18m

  1. Take the bus from South Station, Boston, MA to Port Authority Bus Terminal, New York, NY Peter Pan / ...
  2. Take the bus from New York to Florence, SC

$71 - $121

Drive  •  14h 26m

  1. Drive from Boston to Florence 845.7 miles

$80 - $120

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Last updated: June 29 | Data sourced from: ACAPS, OXFORD

Questions & Answers

The cheapest way to get from Boston to Florence is to bus which costs $70 - $95 and takes 16h.

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The quickest way to get from Boston to Florence is to fly which costs $210 - $1,200 and takes 5h 26m.

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No, there is no direct bus from Boston to Florence. However, there are services departing from Boston South Buses and arriving at Florence, SC via New York, NY. The journey, including transfers, takes approximately 16h.

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No, there is no direct train from Boston station to Florence station. However, there are services departing from Boston South Station and arriving at Florence Amtrak Station via New York Penn Station. The journey, including transfers, takes approximately 16h 19m.

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The distance between Boston and Florence is 739 miles. The road distance is 845.7 miles.

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The best way to get from Boston to Florence without a car is to bus which takes 16h and costs $70 - $95.

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It takes approximately 5h 26m to get from Boston to Florence, including transfers.

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Boston to Florence bus services, operated by Lucky Star Bus, depart from Boston South Buses station.

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Boston to Florence train services, operated by Amtrak, depart from Boston South Station.

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The best way to get from Boston to Florence is to fly which takes 5h 26m and costs $210 - $1,200. Alternatively, you can bus, which costs $70 - $95 and takes 16h, you could also train, which costs $100 - $230 and takes 16h 19m.

Mode details

Map of how to get from Boston to Florence.
Launch map view
  • Distance: 738.9 miles
  • Duration: 5h 26m

What companies run services between Boston, MA, USA and Florence, SC, USA?

American Airlines and JetBlue Airways fly from Boston to Florence hourly. Alternatively, you can take a bus from Boston to Florence via New York and New York, NY in around 16h.

Airlines
American Airlines
Website
aa.com
Flights from Boston to Florence via Charlotte
Ave. Duration
4h 30m
When
Every day
Estimated price
$200 - $1,100
Flights from Boston to Florence via Reagan Washington, Charlotte
Ave. Duration
6h 34m
When
Every day
Estimated price
$200 - $1,100
Flights from Boston to Florence via New York La Guardia, Charlotte
Ave. Duration
7h 34m
When
Monday to Friday
Estimated price
$200 - $1,100
Flights from Boston to Florence via Philadelphia, Charlotte
Ave. Duration
7h 6m
When
Every day
Estimated price
$200 - $1,100
Flights from Boston to Florence via Chicago O'Hare, Charlotte
Ave. Duration
7h 41m
When
Every day
Estimated price
$240 - $1,100
Flights from Boston to Florence via Rochester, Charlotte
Ave. Duration
8h 1m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,100
Flights from Boston to Florence via New York JFK, Charlotte
Ave. Duration
8h 51m
When
Every day
Estimated price
$200 - $1,100
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Boston South Station to New York Penn Station
Ave. Duration
3h 42m
Frequency
Every 3 hours
Estimated price
$35 - $55
Website
amtrak.com
Coach Seat
$35 - $55
Premium
$210 - $290
Flexi Coach Seat
$65 - $100
Business Seat
$65 - $95
Train from New York Penn Station to Florence Amtrak Station
Ave. Duration
11h 37m
Frequency
Twice daily
Estimated price
$70 - $100
Website
amtrak.com
Coach Seat
$70 - $100
Premium
$270 - $380
Flexi Coach Seat
$130 - $210
Business Seat
$140 - $210
Amtrak Northeast Regional

Amtrak’s Northeast Regional train service serves the US’ busy northeast corridor from Virginia to Massachusetts; major stops include Boston, Providence, New York City, Philadelphia, Washington DC and Baltimore. Amenities include Wi-Fi, a quiet car, cafe and business-class seating, and travelling with a small dog or cat is permitted. Book at least 14 days in advance for a cheaper Saver Fare.

Rome2rio's guide to Amtrak Northeast Regional
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Boston South Station to New York Penn Station
Ave. Duration
5h
Frequency
Every 3 hours
Estimated price
$60 - $130
Website
amtrak.com
Reserved Coach Seat
$60 - $130
Business Class Seat
$100 - $180
Bus operators
Lucky Star Bus
Phone
(888) 881-0887 / (617) 269-5468
Email
info@luckystarbus.com
Website
luckystarbus.com
Bus from Boston South Buses to New York
Ave. Duration
5h
Frequency
Hourly
Estimated price
$30
Schedules at
luckystarbus.com
Wanda Coach
Phone
646-630-7186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY to Florence, SC
Ave. Duration
10h
Frequency
4 times a day
Estimated price
$40 - $65
Book at
GoTo Bus
EastWest Bus
Phone
4048498583
Website
eastwestbus.com
Bus from New York - 47 Chrystie St to Florence, SC
Ave. Duration
12h 20m
Frequency
3 times a week
Estimated price
$40 - $65
Schedules at
eastwestbus.com
Book at
gotobus.com
Bus from New York, NY - Allen St to Florence, SC
Ave. Duration
12h 30m
Frequency
Once daily
Estimated price
$40 - $65
Schedules at
eastwestbus.com
Book at
gotobus.com
Peter Pan Bus Lines
Phone
1-800-343-9999
Website
peterpanbus.com
Bus from South Station, Boston, MA to Port Authority Bus Terminal, New York, NY
Ave. Duration
4h 20m
Frequency
Every 3 hours
Estimated price
$35 - $50
Website
peterpanbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Boston South Buses to New York, Ny
Ave. Duration
6h 55m
Frequency
Hourly
Estimated price
$27 - $40
Website
greyhound.com
Economy
$27 - $40
Flexible
$50 - $70
Starline Express
Phone
917-656-4221
Email
nycstarline@gmail.com
Website
starlinebus.com
Bus from New York to Florence, SC
Ave. Duration
11h 30m
Frequency
Twice daily
Estimated price
$55 - $70
Schedules at
gotobus.com
Book at
gotobus.com
Atlanta Tours Inc
Bus from New York to Florence, SC
Ave. Duration
11h 30m
Frequency
Once daily
Estimated price
$55 - $70
Schedules at
gotobus.com
Book at
gotobus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There is no direct flight from Boston Airport to Florence Airport. The quickest flight takes 4h 22m and has one stopover.

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Boston to Florence bus services, operated by Wanda Coach, arrive at Florence, SC station.

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Boston to Florence train services, operated by Amtrak, arrive at Florence Amtrak Station.

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Yes, the driving distance between Boston to Florence is 846 miles. It takes approximately 14h 26m to drive from Boston to Florence.

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American Airlines offers flights from Boston Airport to Florence Airport.

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Book your Boston to Florence train tickets online with Omio and Omio.

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There are 41+ hotels available in Florence. Prices start at $100 USD per night.

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The best way to get from Boston to Boston Airport is to bus which takes 0 min and costs $1 - $11.

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