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How to get fromBoston to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, car or bus (Greyhound, Flixbus)

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There are 6 ways to get from Boston to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Boston Logan Airport (BOS) to Des Moines (DSM)plane plane BOS - DSM
    3h 18m
    $215–948
  2. Bus

    cheapest
    1. Take the bus from Boston to New York Midtownbus bus
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    29h 45m
    $187–356
  3. Train, bus

    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    30h 1m
    $326–711
  4. Drive 1,295.8 mi

    1. Drive from Boston to Des Moinescar car 1,295.8 mi
    22h 2m
    $237–342
  5. Train, bus via Bloomington

    1. Take the train from Boston to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    3. Take the bus from Bloomington-Normal to Des Moinesbus bus
    32h 55m
    $351–771
  6. Bus via Indianapolis

    1. Take the bus from Boston to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    33h 10m
    $229–471

Boston to Des Moines by bus

Calendar17Weekly Buses
Duration29h 45mAverage Duration
Ticket$187Cheapest Price
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Questions & Answers

What companies run services between Boston, MA, USA and Des Moines, IA, USA?

Allegiant Air, Delta, and three other airlines fly from Boston Logan Airport (BOS) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Boston to Des Moines via New York Midtown and Chicago Bus Station in around 29h 45m.

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