Rome2Rio

How to get fromBiloxi to Key Westby plane, bus, ferry, car or bus (Greyhound)

Find Transport to Key West

See all options

There are 5 ways to get from Biloxi to Key West by plane, bus, ferry, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Gulfport-Biloxi Regional Airport

    best
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)planeGPT - EYW
    4h 59m
    $177–756

  2. Bus to Mobile Regional Airport, fly

    cheapest
    1. Take the bus from Biloxi Transit Center to Mobile Bus Stationbus
    2. Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)planeMOB - EYW
    6h 51m
    $129–573

  3. Bus, ferry

    1. Take the bus from Biloxi to Fort MyersbusHouston
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferryFort Myers Beach
    18h 56m
    $280–325

  4. Drive 916.2 mi

    1. Drive from Biloxi to Key Westcar916.2 mi
    16h 19m
    $168–242

  5. Bus

    1. Take the bus from Love's Travel Stop - Biloxi to Dolphin Mall - Miamibus
    2. Take the bus from Miami Airport Station to Big Pine Keybus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    25h 40m
    $171–336

Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW) flights

Calendar32Weekly Planes
Duration7h 6mAverage Duration
Ticket$139Cheapest Price
See schedules

Questions & Answers

What companies run services between Biloxi, MS, USA and Key West, FL, USA?

Delta, American Airlines, and United Airlines fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a vehicle from Biloxi to N Roosevelt & 3rd Street via Love's Travel Stop - Biloxi, Dolphin Mall, Sw 1 St & 1 Ct, Government Ctr.Stat.Rail Northbound, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 25h 40m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Biloxi

Trips to Key West

Popular routes