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How to get fromBiloxi to Chicagoby plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 6 ways to get from Biloxi to Chicago by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gulfport-Biloxi Regional Airport to Chicago Midway International Airport

    best
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Chicago Midway International Airport (MDW)plane plane GPT - MDW
    5h 36m
    $148–648

  2. Fly Gulfport-Biloxi Regional Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Chicago O'Hare International Airport (ORD)plane plane GPT - ORD
    5h 46m
    $103–388

  3. Bus, train

    1. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus Greyhound US0602
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train City of New Orleans
    22h 10m
    $221–507

  4. Bus

    1. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus
    2. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    24h 35m
    $156–302

  5. Drive 899.9 mi

    1. Drive from Biloxi to Chicagocar car 899.9 mi
    14h 55m
    $165–238

  6. Bus to Louis Armstrong New Orleans International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus
    2. Fly from Louis Armstrong New Orleans International Airport (MSY) to Chicago Midway International Airport (MDW)plane plane MSY - MDW
    7h
    $110–584

Biloxi to Chicago by bus and train

Calendar7Weekly Services
Duration22h 10mAverage Duration
Ticket$221Cheapest Price
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Questions & Answers

What companies run services between Biloxi, MS, USA and Chicago, IL, USA?

Delta, American Airlines, and three other airlines fly from Gulfport-Biloxi Regional Airport (GPT) to Chicago Midway International Airport (MDW) 3 times a day. Alternatively, you can take a bus from Biloxi Transit Center to Chicago Bus Station via New Orleans Bus Station and St Louis Bus Station in around 24h 35m.

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