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How to get fromBiloxi to Chicagoby plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 5 ways to get from Biloxi to Chicago by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport

    best
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Chicago O'Hare International Airport (ORD)planeGPT - ORD
    5h 56m
    $138–598

  2. Bus

    cheapest
    1. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus
    2. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus
    24h 35m
    $126–322

  3. Bus, train

    1. Take the bus from Biloxi Transit Center to New Orleans Bus StationbusGreyhound US0602
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union StationtrainCity of New Orleans
    22h 10m
    $171–582

  4. Drive 899.9 mi

    1. Drive from Biloxi to Chicagocar899.9 mi
    14h 51m
    $165–238

  5. Fly to Chicago Midway International Airport

    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Chicago Midway International Airport (MDW)planeGPT - MDW
    6h 48m
    $178–798

Biloxi to Chicago by bus and train

Calendar7Weekly Services
Duration22h 10mAverage Duration
Ticket$171Cheapest Price
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Questions & Answers

What companies run services between Biloxi, MS, USA and Chicago, IL, USA?

Delta, American Airlines, and United Airlines fly from Gulfport-Biloxi Regional Airport (GPT) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, you can take a bus from Biloxi Transit Center to Chicago Bus Station via New Orleans Bus Station and St Louis Bus Station in around 24h 35m.

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