Rome2Rio

How to get fromBiddeford to BuffaloBy train, plane, bus (Amtrak, Greyhound), train (Amtrak), car, or bus

Find Transport to Buffalo

See all options

There are 7 ways to get from Biddeford to Buffalo by train, plane, bus (Amtrak, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Boston Logan Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 23m
    $138–789

  2. Drive 493.4 mi

    cheapest
    1. Drive from Biddeford to Buffalocar car 493.4 mi
    10h 5m
    $90–131

  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus Portland / ...
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    14h 58m
    $100–201

  4. Train (Amtrak)

    1. Take the train from Saco Amtrak Station to Bostontrain train Downeaster
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    16h 14m
    $170–427

  5. Fly Portland to Buffalo Niagara International Airport

    1. Fly from Portland (PWM) to Buffalo Niagara International Airport (BUF)plane plane PWM - BUF
    7h 42m
    $203–1,245

  6. Train to Boston Logan Airport, fly to Rochester, bus

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 42m
    $290–906

  7. Train, bus

    1. Take the train from Saco Amtrak Station to Bostontrain train
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    15h 50m
    $104–247

Biddeford to Buffalo by bus

Calendar7Weekly Buses
Duration14h 58mAverage Duration
Ticket$100Cheapest Price
See schedules

Questions & Answers

What companies run services between Biddeford, ME, USA and Buffalo, NY, USA?

You can take a bus from Saco Transportation Center to Buffalo via Congress St + Forest Ave, Portland, ME, Boston, MA - South Station, and Boston in around 14h 58m. Alternatively, you can take a train from Saco Amtrak Station to Buffalo via Boston, North Station, Back Bay, Boston, and Buffalo Depew Station in around 16h 14m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from Biddeford

Trips to Buffalo

Popular routes