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There are 6 ways to get from Berlin Ostbahnhof to Prague Main Station by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  5h 32m

  1. Take the train from Berlin Hbf to Praha Hlavni Nadrazi Ec

Cheapest option

Bus via S+U Alexanderplatz Bhf/Grunerstr.  •  5h 41m

  1. Take the bus from Berlin Südkreuz to Prague Florenc Central Bus Station Lyon Perrache SNCF Train Station - Berlin Central Bus Station / ...

4 alternative options

Bus  •  6h 36m

  1. Take the bus from S Südkreuz Bhf to Prague Main station 060 / ...

Drive  •  3h 17m

  1. Drive from Berlin Ostbahnhof to Prague Main Station 344.4 km

Fly to Prague  •  6h 42m

  1. Fly from Berlin Brandenburg Apt (BER) to Prague (PRG) BER - PRG

Fly to Dresden, bus  •  7h 58m

  1. Fly from Berlin Brandenburg Apt (BER) to Dresden (DRS) BER - DRS
  2. Take the bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Station

Berlin Ostbahnhof to Prague Main Station by train and walk

The journey time between Berlin Ostbahnhof and Prague Main Station is around 4h 36m and covers a distance of around 375 km. This includes an average layover time of around 6 min. The fastest journey normally takes 4h 36m. Operated by S-Bahn Berlin, Deutsche Bahn Regional, Bahn DE and others, the Berlin Ostbahnhof to Prague Main Station service departs from S Ostbahnhof and arrives in Prague Main Station. Typically 35 services run weekly, although weekend and holiday schedules can vary so check in advance.

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Average journey times

Time on transportation:
4h 30m
Layover time:
6 min
Total time:
4h 36m

Route information

Fastest journey time:
4h 36m
Journey distance:
375 km
Services per week:
35
Cheapest price:
958 Kč
Carbon emissions:
19 kg CO2

First and last service

First service departs at:
06:59
Last service departs at:
16:59

The schedules shown below are for the next available departures.

Berlin Ostbahnhof to Prague Main Station train and walk schedules

Questions & Answers

The cheapest way to get from Berlin Ostbahnhof to Prague Main Station is to bus via S+U Alexanderplatz Bhf/Grunerstr. which costs €15 - €28 and takes 5h 41m.

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The fastest way to get from Berlin Ostbahnhof to Prague Main Station is to drive which takes 3h 17m and costs €35 - €60.

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No, there is no direct bus from Berlin Ostbahnhof to Prague Main Station station. However, there are services departing from S Ostbahnhof and arriving at Prague Florenc Central Bus Station via S+U Alexanderpl./Grunerstr.(Bln) [Grunerstr.] and Berlin Südkreuz. The journey, including transfers, takes approximately 5h 41m.

More details

No, there is no direct train from Berlin Ostbahnhof to Prague Main Station. However, there are services departing from S Ostbahnhof and arriving at Praha Hlavni Nadrazi via Berlin Hbf. The journey, including transfers, takes approximately 5h 32m.

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The distance between Berlin Ostbahnhof and Prague Main Station is 279 km. The road distance is 344.4 km.

Get driving directions

The best way to get from Berlin Ostbahnhof to Prague Main Station without a car is to train which takes 5h 32m and costs €35 - €95.

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It takes approximately 5h 32m to get from Berlin Ostbahnhof to Prague Main Station, including transfers.

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Berlin Ostbahnhof to Prague Main Station bus services, operated by RegioJet, depart from Berlin Südkreuz station.

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Berlin Ostbahnhof to Prague Main Station train services, operated by Deutsche Bahn Eurocity, depart from Berlin Hbf station.

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The best way to get from Berlin Ostbahnhof to Prague Main Station is to train which takes 5h 32m and costs €35 - €95. Alternatively, you can bus via S+U Alexanderplatz Bhf/Grunerstr., which costs €15 - €28 and takes 5h 41m, you could also fly, which costs €27 - €230 and takes 6h 42m.

Mode details

Map of how to get from Berlin Ostbahnhof to Prague Main Station.
Launch map view
  • Distance: 278.7 km
  • Duration: 5h 32m

What companies run services between Berlin Ostbahnhof, Germany and Prague Main Station, Czech Republic?

Deutsche Bahn Eurocity operates a train from Berlin Hbf to Praha Hlavni Nadrazi 5 times a day. Tickets cost 900 Kč - 1 300 Kč and the journey takes 4h 20m. Alternatively, RegioJet operates a bus from Berlin Südkreuz to Prague Florenc Central Bus Station hourly. Tickets cost 260 Kč - 370 Kč and the journey takes 4h 15m. FlixBus also services this route every 2 hours.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Berlin Brandenburg Apt to Prague via Frankfurt
Ave. Duration
3h 45m
When
Every day
Estimated price
2 800 Kč - 11 000 Kč
Flights from Berlin Brandenburg Apt to Prague via Munich
Ave. Duration
5h
When
Every day
Estimated price
2 800 Kč - 11 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Frankfurt
Ave. Duration
3h 26m
When
Every day
Estimated price
2 700 Kč - 12 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Munich
Ave. Duration
3h 57m
When
Every day
Estimated price
2 700 Kč - 12 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Zurich
Ave. Duration
3h 50m
When
Monday, Thursday, Friday and Sunday
Estimated price
2 800 Kč - 11 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Frankfurt, Munich
Ave. Duration
5h 25m
When
Monday to Friday
Estimated price
2 900 Kč - 13 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Munich, Frankfurt
Ave. Duration
6h 10m
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
2 900 Kč - 13 000 Kč
KLM
Website
klm.com
Flights from Berlin Brandenburg Apt to Prague via Amsterdam Schiphol
Ave. Duration
4h 46m
When
Every day
Estimated price
2 900 Kč - 11 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Amsterdam Schiphol
Ave. Duration
4h 35m
When
Every day
Estimated price
3 300 Kč - 10 000 Kč
Austrian Airlines
Website
austrian.com
Flights from Berlin Brandenburg Apt to Prague via Vienna
Ave. Duration
4h 5m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
3 600 Kč - 14 000 Kč
Brussels Airlines
Website
brusselsairlines.com
Flights from Berlin Brandenburg Apt to Prague via Brussels
Ave. Duration
3h 57m
When
Every day
Estimated price
3 200 Kč - 10 000 Kč
easyJet
Website
easyjet.com
Flights from Berlin Brandenburg Apt to Prague via Amsterdam Schiphol
Ave. Duration
4h 20m
When
Monday, Thursday and Sunday
Estimated price
2 100 Kč - 6 500 Kč
Flights from Berlin Brandenburg Apt to Prague via Manchester
Ave. Duration
6h 25m
When
Monday
Estimated price
2 100 Kč - 6 500 Kč
Swiss
Website
swiss.com
Flights from Berlin Brandenburg Apt to Prague via Zurich
Ave. Duration
4h 25m
When
Wednesday, Thursday and Friday
Estimated price
2 900 Kč - 10 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Zurich
Ave. Duration
3h 50m
When
Monday, Thursday, Friday and Sunday
Estimated price
2 800 Kč - 11 000 Kč
Air France
Website
airfrance.com
Flights from Berlin Brandenburg Apt to Prague via Paris CDG
Ave. Duration
5h 35m
When
Every day
Estimated price
3 500 Kč - 12 000 Kč
Ryanair
Website
ryanair.com
Flights from Berlin Brandenburg Apt to Prague via Milan Bergamo
Ave. Duration
6h 15m
When
Thursday and Saturday
Estimated price
600 Kč - 5 500 Kč
Flights from Berlin Brandenburg Apt to Prague via London Stansted
Ave. Duration
6h 50m
When
Tuesday
Estimated price
600 Kč - 5 500 Kč
Eurowings
Website
eurowings.com
Flights from Berlin Brandenburg Apt to Prague via Cologne Bonn
Ave. Duration
6h 50m
When
Friday
Estimated price
1 900 Kč - 11 000 Kč
Flights from Berlin Brandenburg Apt to Dresden via Dusseldorf
Ave. Duration
3h 25m
When
Wednesday, Thursday and Friday
Estimated price
1 900 Kč - 8 500 Kč
Air Baltic
Website
airbaltic.com
Flights from Berlin Brandenburg Apt to Prague via Riga
Ave. Duration
4h 25m
When
Monday and Friday
Estimated price
3 400 Kč - 10 000 Kč
LOT
Website
lot.com
Flights from Berlin Brandenburg Apt to Prague via Warsaw Chopin
Ave. Duration
4h 30m
When
Monday to Saturday
Estimated price
2 100 Kč - 6 000 Kč
Vueling Airlines
Website
vueling.com
Flights from Berlin Brandenburg Apt to Prague via Barcelona
Ave. Duration
5h 55m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
3 200 Kč - 18 000 Kč
Luxair
Website
luxair.lu
Flights from Berlin Brandenburg Apt to Prague via Luxembourg
Ave. Duration
6h 35m
When
Monday
Estimated price
4 800 Kč - 14 000 Kč
Train operators
Deutsche Bahn Eurocity

Deutsche Bahn’s EuroCity (EC) trains connect German cities to major cities in neighbouring European countries, and are operated in conjunction with their national train company. All EC trains offer First and Standard class; cars are air-conditioned and food and drinks are available onboard. Tickets can be booked up to 180 days in advance of travel. Seat reservations are not compulsory but are recommended for popular routes.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Berlin Hbf to Praha Hlavni Nadrazi
Ave. Duration
4h 20m
Frequency
5 times a day
Estimated price
900 Kč - 1 300 Kč
Website
reiseauskunft.bahn.de
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Berlin Südkreuz to Prague Florenc Central Bus Station
Ave. Duration
4h 15m
Frequency
Hourly
Estimated price
260 Kč - 370 Kč
Website
RegioJet
Bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Station
Ave. Duration
1h 55m
Frequency
Hourly
Estimated price
130 Kč - 190 Kč
Website
RegioJet
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 30 300 137 300
Email
service@flixbus.com
Website
flixbus.de
Bus from S Südkreuz Bhf to Prague
Ave. Duration
4h 20m
Frequency
Every 2 hours
Estimated price
450 Kč - 550 Kč
Website
flixbus.co.uk
Bus from S Südkreuz Bhf to Prague Main station
Ave. Duration
4h 40m
Frequency
Every 2 hours
Estimated price
460 Kč - 550 Kč
Website
flixbus.co.uk
Bus from Dresden Hauptbahnhof to Prague
Ave. Duration
1h 50m
Frequency
Every 4 hours
Estimated price
250 Kč - 310 Kč
Website
flixbus.co.uk
Frequently asked questions
Is there Wi-Fi on FlixBus?
Yes - FlixBus offers free Wi-Fi
Are there power outlets on FlixBus?
Yes
Does FlixBus offer meals or snacks?
Yes - snacks and drinks may be purchased from the driver. Please note, this is not available on all services.
For more information, please visit this page
Racic Eurobus
Phone
+359-887-208-506
Email
racic_bg@yahoo.com
Website
racicbg.com
Bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Station
Ave. Duration
2h
Frequency
Once daily
Website
Racic Eurobus
Comati PSG
Phone
0040 723 450 475
Email
info@comati-psg.ro
Website
comati-psg.ro
Bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Station
Ave. Duration
3h
Frequency
4 times a week
Estimated price
2 000 Kč - 2 400 Kč
Website
Comati PSG
Radina VIP
Phone
+359 879 321 588
Email
radinavip@gmail.com
Website
radinavip.com
Bus from Dresden to Prague Florenc
Ave. Duration
3h
Frequency
Once a week
Estimated price
2 300 Kč - 2 900 Kč
Website
Radina VIP

Want to know more about travelling around Czechia

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There is no direct flight from Berlin Brandenburg Apt Airport to Prague Airport. The quickest flight takes 3h 15m and has one stopover.

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Berlin Ostbahnhof to Prague Main Station bus services, operated by RegioJet, arrive at Prague Florenc Central Bus Station.

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Berlin Ostbahnhof to Prague Main Station train services, operated by Deutsche Bahn Eurocity, arrive at Praha Hlavni Nadrazi station.

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Yes, the driving distance between Berlin Ostbahnhof to Prague Main Station is 344 km. It takes approximately 3h 17m to drive from Berlin Ostbahnhof to Prague Main Station.

Get driving directions

Swiss, Air Baltic, LOT and 10 other airlines offer flights from Berlin Brandenburg Apt Airport to Prague Airport.

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There are 901+ hotels available in Prague Main Station. Prices start at 2 000 Kč per night.

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The best way to get from Berlin Ostbahnhof to Berlin Brandenburg Apt Airport is to train which takes 39 min and costs €2 - €9.

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