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How to get fromBaltimore to St. Louisby plane, bus (Greyhound), train (Amtrak), car, train or subway

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There are 8 ways to get from Baltimore to St. Louis by plane, bus (Greyhound), train (Amtrak), car, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Baltimore-Washington International Airport

    best
    1. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    4h 46m
    $215–465

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus Greyhound US0430
    2. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    20h 50m
    $101–325

  3. Train via Washington

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    25h 25m
    $139–1,020

  4. Drive 806 mi

    1. Drive from Baltimore to St. Louiscar car 806 mi
    13h 55m
    $148–213

  5. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    5h 23m
    $219–1,764

  6. Train, subway to Washington Dulles International Airport, fly

    1. Take the train from Baltimore Penn Station to New Carrollton Amtrak Stationtrain train
    2. Take the subway from New Carrollton, Orange Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Lambert–St. Louis International Airport (STL)plane plane IAD - STL
    6h 7m
    $117–859

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Baltimore Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    6h 12m
    $226–1,092

  8. Train (Amtrak)

    1. Take the train from Baltimore Penn Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    31h 13m
    $155–698

Baltimore to St. Louis by bus (Greyhound)

Calendar7Weekly Buses
Duration20h 50mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

What companies run services between Baltimore, MD, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Baltimore Downtown Bus Station to St Louis Bus Station via Harrisburg Bus Station in around 20h 50m.

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