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How to get fromBaltimore to St. Louisby plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, subway, or bus (Greyhound)

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There are 9 ways to get from Baltimore to St. Louis by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, subway, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Baltimore-Washington International Airport

    best
    1. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    4h 36m
    $125–705

  2. Train, subway to Washington Dulles International Airport, fly

    cheapest
    1. Take the train from Baltimore Penn Station to New Carrollton Amtrak Stationtrain train
    2. Take the subway from New Carrollton, Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Lambert–St. Louis International Airport (STL)plane plane IAD - STL
    6h 34m
    $107–615

  3. Bus via Philadelphia

    1. Take the bus from Baltimore Downtown Bus Station to Philadelphia Bus Stationbus bus Greyhound US0320 / ...
    2. Take the bus from Philadelphia Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    23h
    $176–277

  4. Train via Washington

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    25h 50m
    $564–1,447

  5. Drive  806 mi

    1. Drive from Baltimore to St. Louiscar car 806 mi
    14h 1m
    $138–199

  6. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    5h 35m
    $159–1,414

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Baltimore Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    5h 58m
    $147–1,356

  8. Bus (Greyhound)

    1. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus Greyhound US0430 / ...
    2. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    23h 25m
    $167–260

  9. Train (Amtrak)

    1. Take the train from Baltimore Penn Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    31h 38m
    $674–1,044

Baltimore to St. Louis by bus

Calendar21Weekly Buses
Duration23hAverage Duration
Ticket$176Cheapest Price
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Comparing Your Travel Options

Map of how to get from Baltimore to St. Louis.ExpandLaunch map view
  • Distance: 758.9 mi
  • Duration: 4h 36m

What companies run services between Baltimore, MD, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Baltimore Downtown Bus Station to St Louis Bus Station via Philadelphia Bus Station in around 23h.

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Want to know more about travelling around United States

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Need to know: Greyhound

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