There are 8 ways to get from Baltimore to Knoxville by plane, train, subway, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Baltimore to Knoxville  •  4 h 59 min

  1. Fly from Baltimore (BWI) to Knoxville (TYS) BWI - TYS

$257 - $1,072

Cheapest option

Bus  •  17 h 50 min

  1. Take the bus from Baltimore Downtown, Md to Winston Salem, Nc 1051
  2. Take the bus from Winston Salem, Nc to Knoxville, Tn 4845

$73 - $179

6 alternative options

Train to Reagan Washington, fly to Knoxville  •  4 h 9 min

  1. Take the train from Baltimore Penn Station to Washington Union Station
  2. Fly from Reagan Washington (DCA) to Knoxville (TYS) DCA - TYS

$269 - $832

Train, subway to Washington Dulles, fly to Knoxville  •  4 h 49 min

  1. Take the train from Baltimore Penn Station to Washington Union Station
  2. Take the subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
  3. Fly from Washington Dulles (IAD) to Knoxville (TYS) IAD - TYS

$335 - $839

Train to Philadelphia, fly to Knoxville  •  4 h 48 min

  1. Take the train from Baltimore Penn Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Knoxville (TYS) PHL - TYS

$311 - $884

Fly Baltimore to Asheville, drive  •  5 h 12 min

  1. Fly from Baltimore (BWI) to Asheville (AVL) BWI - AVL
  2. Drive from Asheville to Knoxville

$99 - $480

Train, bus  •  14 h 52 min

  1. Take the train from Baltimore Penn Station to Greensboro Galyon Transportation Center Crescent / ...
  2. Take the bus from Greensboro, Nc to Knoxville, Tn 4845

$86 - $223

Drive  •  8 h 47 min

  1. Drive from Baltimore to Knoxville 522.8 miles

$50 - $75

Questions & Answers

No, there is no direct bus from Baltimore to Knoxville. However, there are services departing from Baltimore Downtown, Md and arriving at Knoxville, Tn via Winston Salem, Nc. The journey, including transfers, takes approximately 17 h 50 min.

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The distance between Baltimore and Knoxville is 464 miles. The road distance is 522.8 miles.

Get driving directions

The best way to get from Baltimore to Knoxville without a car is to train and bus which takes 14 h 52 min and costs .

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It takes approximately 4 h 59 min to get from Baltimore to Knoxville, including transfers.

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Baltimore to Knoxville bus services, operated by Greyhound USA, depart from Baltimore Downtown, Md station.

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The best way to get from Baltimore to Knoxville is to fly which takes 4 h 59 min and costs . Alternatively, you can bus, which costs and takes 17 h 50 min.

Mode details

There is no direct flight from Baltimore Airport to Knoxville Airport. The quickest flight takes 3 h 10 min and has one stopover.

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Baltimore to Knoxville bus services, operated by Greyhound USA, arrive at Knoxville, Tn station.

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Yes, the driving distance between Baltimore to Knoxville is 523 miles. It takes approximately 8 h 47 min to drive from Baltimore to Knoxville.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Baltimore Airport to Knoxville Airport.

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Map of how to get from Baltimore to Knoxville.
Launch map view
  • Distance: 463.9 miles
  • Duration: 4 h 59 min

What companies run services between Baltimore, MD, USA and Knoxville, TN, USA?

American Airlines, Delta and United Airlines fly from Baltimore to Knoxville hourly. Alternatively, you can take a bus from Baltimore to Knoxville via Winston Salem, Nc in around 17 h 50 min.

Airlines
American Airlines
Website
aa.com
Flights from Baltimore to Knoxville via Charlotte
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$200 - $1,000
Flights from Baltimore to Knoxville via Chicago O'Hare
Ave. Duration
5 h 38 min
When
Every day
Estimated price
$240 - $1,100
Flights from Baltimore to Knoxville via Dallas/Ft.Worth
Ave. Duration
6 h 27 min
When
Monday, Wednesday, Thursday and Friday
Estimated price
$320 - $1,300
Flights from Baltimore to Knoxville via Miami
Ave. Duration
6 h 32 min
When
Monday to Saturday
Estimated price
$300 - $1,200
Flights from Reagan Washington to Knoxville
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$250 - $800
Flights from Reagan Washington to Knoxville via Charlotte
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$250 - $800
Flights from Reagan Washington to Knoxville via Philadelphia
Ave. Duration
3 h 53 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $800
Flights from Washington Dulles to Knoxville via Charlotte
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$400 - $800
Flights from Philadelphia to Knoxville
Ave. Duration
1 h 54 min
When
Every day
Estimated price
$350 - $1,100
Flights from Philadelphia to Knoxville via Charlotte
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$350 - $1,100
Flights from Philadelphia to Knoxville via Reagan Washington
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$350 - $1,100
Flights from Baltimore to Asheville via Charlotte
Ave. Duration
3 h 31 min
When
Every day
Estimated price
$380 - $950
Delta
Website
delta.com
Flights from Baltimore to Knoxville via Atlanta
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$200 - $1,000
Flights from Baltimore to Knoxville via Detroit
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$210 - $1,100
Flights from Baltimore to Knoxville via Minneapolis
Ave. Duration
6 h 23 min
When
Every day
Estimated price
$280 - $1,200
Flights from Reagan Washington to Knoxville via Atlanta
Ave. Duration
3 h 49 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$420 - $1,400
Flights from Reagan Washington to Knoxville via Detroit
Ave. Duration
4 h 14 min
When
Monday to Saturday
Estimated price
$420 - $1,400
Flights from Washington Dulles to Knoxville via Atlanta
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$220 - $1,400
Flights from Philadelphia to Knoxville via Atlanta
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$410 - $1,200
Flights from Philadelphia to Knoxville via Detroit
Ave. Duration
4 h 17 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$410 - $1,200
United Airlines
Website
united.com
Flights from Baltimore to Knoxville via Chicago O'Hare
Ave. Duration
5 h 32 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$250 - $1,200
Flights from Washington Dulles to Knoxville
Ave. Duration
1 h 39 min
When
Every day
Estimated price
$290 - $750
Flights from Philadelphia to Knoxville via Washington Dulles
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$370 - $1,200
Allegiant Air
Website
allegiantair.com
Flights from Baltimore to Asheville
Ave. Duration
1 h 26 min
When
Thursday and Sunday
Estimated price
$130 - $430
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Baltimore Penn Station to Washington Union Station
Ave. Duration
40 min
Frequency
Hourly
Estimated price
$55 - $160
Website
amtrak.com
Business Seat
$55 - $150
First Class Seat
$120 - $160
Train from Baltimore Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Metro Washington DC
Phone
202-637-7000
Website
wmata.com
Subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
Ave. Duration
37 min
Frequency
Every 15 minutes
Estimated price
$3 - $6
Schedules at
wmata.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Baltimore Penn Station to Greensboro Galyon Transportation Center
Ave. Duration
7 h 7 min
Frequency
Twice daily
Estimated price
$55 - $150
Website
amtrak.com
Coach Seat
$55 - $85
Flexi Coach Seat
$95 - $140
Business Coach Seat
$100 - $150
Room
$250 - $350
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Greensboro, Nc to Knoxville, Tn
Ave. Duration
6 h 45 min
Frequency
Every 2 hours
Estimated price
$30 - $80
Website
greyhound.com
Economy
$30 - $55
Flexible
$60 - $80
Bus from Baltimore Downtown, Md to Winston Salem, Nc
Ave. Duration
11 h 20 min
Frequency
Every 4 hours
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Winston Salem, Nc to Knoxville, Tn
Ave. Duration
5 h 30 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
greyhound.com
Economy
$30 - $50
Flexible
$55 - $75

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More Questions & Answers

Book your Baltimore to Knoxville bus tickets online with Greyhound and Greyhound.

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There are 100+ hotels available in Knoxville. Prices start at $56 USD per night.

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The best way to get from Baltimore to Baltimore Airport is to tram which takes 31 min and costs .

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