There are 8 ways to get from Baltimore to Greenville by train, plane, subway, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Reagan Washington, fly to Greenville/Spartanburg  •  4 h 2 min

  1. Take the train from Baltimore Penn Station to Washington Union Station
  2. Fly from Reagan Washington (DCA) to Greenville/Spartanburg (GSP) DCA - GSP

$214 - $507

Cheapest option

Bus EastWest Bus  •  12 h 41 min

  1. Take the bus from Baltimore, MD to Greenville, SC Golden Horse

$63 - $74

6 alternative options

Train, subway to Washington Dulles, fly to Greenville/Spartanburg  •  4 h 42 min

  1. Take the train from Baltimore Penn Station to Washington Union Station
  2. Take the subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
  3. Fly from Washington Dulles (IAD) to Greenville/Spartanburg (GSP) IAD - GSP

$220 - $664

Train to Philadelphia, fly to Greenville/Spartanburg  •  4 h 43 min

  1. Take the train from Baltimore Penn Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Greenville/Spartanburg (GSP) PHL - GSP

$276 - $809

Fly Baltimore to Charlotte, train  •  6 h 55 min

  1. Fly from Baltimore (BWI) to Charlotte (CLT) BWI - CLT
  2. Take the train from Charlotte Amtrak to Greenville Amtrak

$134 - $335

Train  •  11 h 46 min

  1. Take the train from Baltimore Penn Station to Greenville Amtrak Crescent

$75 - $220

Bus Greyhound USA  •  16 h 25 min

  1. Take the bus from Baltimore Downtown, Md to Greenville, Sc 1051

$79 - $169

Drive  •  9 h 13 min

  1. Drive from Baltimore to Greenville 537.6 miles

$50 - $80

Questions & Answers

The cheapest way to get from Baltimore to Greenville is to drive which costs $50 - $80 and takes 9 h 13 min.

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The quickest way to get from Baltimore to Greenville is to train and fly which costs $210 - $550 and takes 4 h 2 min.

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Yes, there is a direct train departing from Baltimore Penn Station station and arriving at Greenville Amtrak. Services depart once daily, and operate every day. The journey takes approximately 11 h 46 min.

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The distance between Baltimore and Greenville is 445 miles. The road distance is 537.6 miles.

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The best way to get from Baltimore to Greenville without a car is to train which takes 11 h 46 min and costs $75 - $220.

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It takes approximately 4 h 2 min to get from Baltimore to Greenville, including transfers.

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Baltimore to Greenville train services, operated by Amtrak, arrive at Baltimore Penn Station.

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The best way to get from Baltimore to Greenville is to train which takes 11 h 46 min and costs $75 - $220. Alternatively, you can bus, which costs $60 - $75 and takes 12 h 41 min.

Mode details

The quickest flight from Reagan Washington Airport to Greenville/Spartanburg Airport is the direct flight which takes 1 h 37 min.

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Baltimore to Greenville train services, operated by Amtrak, arrive at Greenville Amtrak station.

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Map of how to get from Baltimore to Greenville.
Launch map view
  • Distance: 444.7 miles
  • Duration: 4 h 2 min

What companies run services between Baltimore, MD, USA and Greenville, SC, USA?

Amtrak operates a train from Baltimore to Greenville once daily. Tickets cost $75 - $220 and the journey takes 11 h 46 min. Alternatively, EastWest Bus operates a bus from Baltimore to Greenville once daily. Tickets cost $43 and the journey takes 9 h 59 min.

Airlines
American Airlines
Website
aa.com
Flights from Reagan Washington to Greenville/Spartanburg
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$180 - $600
Flights from Reagan Washington to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 27 min
When
Every day
Estimated price
$180 - $600
Flights from Reagan Washington to Greenville/Spartanburg via Philadelphia
Ave. Duration
4 h 4 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $600
Flights from Washington Dulles to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$220 - $900
Flights from Philadelphia to Greenville/Spartanburg
Ave. Duration
1 h 51 min
When
Every day
Estimated price
$200 - $950
Flights from Philadelphia to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$200 - $950
Flights from Baltimore to Charlotte
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$180 - $490
Southwest Airlines
Website
southwest.com
Flights from Philadelphia to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 5 min
When
Saturday
Estimated price
$250 - $800
Flights from Baltimore to Charlotte
Ave. Duration
1 h 28 min
When
Every day
Estimated price
$210 - $550
Delta
Website
delta.com
Flights from Reagan Washington to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$220 - $800
Flights from Washington Dulles to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 50 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $900
Flights from Philadelphia to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 48 min
When
Monday to Friday
Estimated price
$200 - $750
Flights from Philadelphia to Greenville/Spartanburg via Detroit
Ave. Duration
4 h 15 min
When
Monday to Friday
Estimated price
$200 - $750
United Airlines
Website
united.com
Flights from Washington Dulles to Greenville/Spartanburg
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$240 - $950
Flights from Philadelphia to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 51 min
When
Every day
Estimated price
$290 - $1,000
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Baltimore Penn Station to Washington Union Station
Ave. Duration
40 min
Frequency
Hourly
Estimated price
$55 - $160
Website
amtrak.com
Business Seat
$55 - $150
First Class Seat
$120 - $160
Train from Baltimore Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Metro Washington DC
Phone
202-637-7000
Website
wmata.com
Subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
Ave. Duration
37 min
Frequency
Every 15 minutes
Estimated price
$3 - $6
Schedules at
wmata.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Charlotte Amtrak to Greenville Amtrak
Ave. Duration
2 h 9 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Train from Baltimore Penn Station to Greenville Amtrak
Ave. Duration
11 h 46 min
Frequency
Once daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Bus operators
EastWest Bus
Phone
4048498583
Website
eastwestbus.com
Bus from Baltimore, MD to Greenville, SC
Ave. Duration
9 h 59 min
Frequency
Once daily
Estimated price
$43
Schedules at
eastwestbus.com
Book at
eastwestbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Baltimore Downtown, Md to Greenville, Sc
Ave. Duration
16 h 15 min
Frequency
Every 4 hours
Estimated price
$55 - $150
Website
greyhound.com
Economy
$55 - $95
Flexible
$110 - $150

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More Questions & Answers

Yes, the driving distance between Baltimore to Greenville is 538 miles. It takes approximately 9 h 13 min to drive from Baltimore to Greenville.

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Delta and American Airlines offer flights from Reagan Washington Airport to Greenville/Spartanburg Airport.

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Book your Baltimore to Greenville train tickets online with Rome2rio.

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There are 83+ hotels available in Greenville. Prices start at $69 USD per night.

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The best way to get from Baltimore to Baltimore Airport is to tram which takes 31 min and costs $2.

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