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How to get fromBaltimore to Des Moinesby train, plane, bus (Greyhound), bus, car, subway or bus (Greyhound, Flixbus)

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There are 9 ways to get from Baltimore to Des Moines by train, plane, bus (Greyhound), bus, car, subway, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly

    best
    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)plane plane DCA - DSM
    5h 22m
    $323–2,182

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    26h 14m
    $118–290

  3. Train, bus via Washington

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    27h 23m
    $134–930

  4. Drive 1,006.3 mi

    1. Drive from Baltimore to Des Moinescar car 1,006.3 mi
    17h 3m
    $184–266

  5. Fly from Baltimore-Washington International Airport

    1. Fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM)plane plane BWI - DSM
    6h 25m
    $179–873

  6. Train to Philadelphia International Airport, fly

    1. Take the train from Baltimore Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    5h 49m
    $220–1,570

  7. Train, subway to Washington Dulles International Airport, fly

    1. Take the train from Baltimore Penn Station to New Carrollton Amtrak Stationtrain train
    2. Take the subway from New Carrollton, Orange Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Des Moines (DSM)plane plane IAD - DSM
    7h 42m
    $181–1,077

  8. Bus via Harrisburg

    1. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    26h 49m
    $146–395

  9. Train, bus

    1. Take the train from Baltimore Penn Station to Chicago Union Stationtrain train Cardinal
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    33h 10m
    $160–611

Baltimore to Des Moines by bus (Greyhound)

Calendar14Weekly Buses
Duration26h 14mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

What companies run services between Baltimore, MD, USA and Des Moines, IA, USA?

You can take a bus from Baltimore Downtown Bus Station to Des Moines via Chicago Bus Station in around 26h 14m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM) hourly.

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Need to know: Greyhound

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