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How to get fromBaltimore to Des Moinesby train, plane, bus (Greyhound), bus, car, subway or bus (Greyhound, Flixbus)

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There are 10 ways to get from Baltimore to Des Moines by train, plane, bus (Greyhound), bus, car, subway, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly

    best
    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)planeDCA - DSM
    5h 12m
    $313–2,082

  2. Bus

    cheapest
    1. Take the bus from Baltimore Downtown Bus Station to Chicago Bus StationbusGreyhound US0164
    2. Take the bus from Chicago to Des MoinesbusChicago
    26h 50m
    $135–398

  3. Train, bus

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain
    3. Take the bus from Chicago to Des Moinesbus
    27h 58m
    $149–990

  4. Drive 1,006.3 mi

    1. Drive from Baltimore to Des Moinescar1,006.3 mi
    16h 52m
    $184–266

  5. Fly from Baltimore-Washington International Airport

    1. Fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM)planeBWI - DSM
    6h 10m
    $169–823

  6. Train to Philadelphia International Airport, fly

    1. Take the train from Baltimore Penn Station to 30th Street Stationtrain
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)planePHL - DSM
    5h 49m
    $200–1,520

  7. Train, subway to Washington Dulles International Airport, fly

    1. Take the train from Baltimore Penn Station to New Carrollton Amtrak Stationtrain
    2. Take the subway from New Carrollton, Orange Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
    3. Fly from Washington Dulles International Airport (IAD) to Des Moines (DSM)planeIAD - DSM
    7h 52m
    $171–1,027

  8. Bus via Harrisburg

    1. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus
    3. Take the bus from Chicago to Des Moinesbus
    27h 25m
    $167–444

  9. Train, bus via Galesburg

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
    4. Take the bus from Galesburg to Burlingtonbus
    5. Take the bus from Burlington to Des Moinesbus
    29h 30m
    $189–1,045

  10. Train, bus #2

    1. Take the train from Baltimore Penn Station to Chicago Union StationtrainCardinal
    2. Take the bus from Chicago to Des MoinesbusChicago
    33h 46m
    $182–714

Baltimore to Des Moines by bus

Calendar14Weekly Buses
Duration26h 50mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

What companies run services between Baltimore, MD, USA and Des Moines, IA, USA?

You can take a bus from Baltimore Downtown Bus Station to Des Moines via Chicago in around 26h 50m. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM) hourly.

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Need to know: Greyhound

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