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How to get fromBaltimore to Des Moinesby plane, bus (Greyhound), train, bus, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Baltimore to Des Moines by plane, bus (Greyhound), train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Baltimore-Washington International Airport

    best
    1. Fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM)plane plane BWI - DSM
    6h 21m
    $189–923

  2. Bus via Harrisburg

    cheapest
    1. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    26h 45m
    $168–315

  3. Bus (Greyhound)

    1. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    26h 10m
    $179–348

  4. Train, bus

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    27h 44m
    $269–1,140

  5. Drive 1,006.3 mi

    1. Drive from Baltimore to Des Moinescar car 1,006.3 mi
    17h 3m
    $184–266

  6. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)plane plane DCA - DSM
    5h 28m
    $323–2,182

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Baltimore Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    5h 46m
    $282–1,823

  8. Train, bus via Bloomington

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    30h 37m
    $294–1,205

  9. Train, bus #2

    1. Take the train from Baltimore Penn Station to Chicago Union Stationtrain train Cardinal
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    33h 31m
    $328–697

Baltimore to Des Moines by bus (Greyhound)

Calendar14Weekly Buses
Duration26h 10mAverage Duration
Ticket$179Cheapest Price
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Questions & Answers

What companies run services between Baltimore, MD, USA and Des Moines, IA, USA?

Delta, Southwest Airlines, and two other airlines fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Baltimore Downtown Bus Station to Des Moines via Chicago Bus Station in around 26h 10m.

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