There are 8 ways to get from Baltimore to Buffalo–Depew Station by plane, train, subway, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Baltimore to Buffalo  •  4 h 16 min

  1. Fly from Baltimore (BWI) to Buffalo (BUF) BWI - BUF

$124 - $604

Cheapest option

Bus  •  13 h 24 min

  1. Take the bus from Baltimore, MD to Buffalo

$62 - $127

6 alternative options

Fly Baltimore to Rochester, train  •  5 h 9 min

  1. Fly from Baltimore (BWI) to Rochester (ROC) BWI - ROC
  2. Take the train from Rochester Amtrak to Buffalo Depew Station Amtrak

$148 - $373

Train to Reagan Washington, fly to Buffalo  •  5 h 7 min

  1. Take the train from Baltimore Penn Station Amtrak to Washington Union Station Amtrak
  2. Fly from Reagan Washington (DCA) to Buffalo (BUF) DCA - BUF

$176 - $634

Train, subway to Washington Dulles, fly to Buffalo  •  5 h 58 min

  1. Take the train from Baltimore Penn Station Amtrak to Washington Union Station Amtrak
  2. Take the subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
  3. Fly from Washington Dulles (IAD) to Buffalo (BUF) IAD - BUF

$182 - $721

Train to Philadelphia, fly to Buffalo  •  5 h 46 min

  1. Take the train from Baltimore Penn Station Amtrak to Philadelphia 30th Street Station Amtrak
  2. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$238 - $916

Train  •  11 h 23 min

  1. Take the train from Baltimore Penn Station Amtrak to New York Penn Station
  2. Take the train from New York Penn Station to Albany-Rensselaer Amtrak
  3. Take the train from Albany-Rensselaer Amtrak to Buffalo Depew Station Amtrak

$170 - $354

Drive  •  6 h 52 min

  1. Drive from Baltimore to Buffalo–Depew Station 358.9 miles

$35 - $55

Questions & Answers

The cheapest way to get from Baltimore to Buffalo–Depew Station is to drive which costs $35 - $55 and takes 6 h 52 min.

More details

The quickest way to get from Baltimore to Buffalo–Depew Station is to fly which costs $120 - $650 and takes 4 h 16 min.

More details

The distance between Baltimore and Buffalo–Depew Station is 275 miles. The road distance is 358.9 miles.

Get driving directions

It takes approximately 4 h 16 min to get from Baltimore to Buffalo–Depew Station, including transfers.

More details

No, there is no direct train from Baltimore station to Buffalo–Depew Station station. However, there are services departing from Baltimore Penn Station Amtrak and arriving at Buffalo Depew Station Amtrak via New York Penn Station and Albany-Rensselaer Amtrak. The journey, including transfers, takes approximately 11 h 23 min.

More details

What companies run services between Baltimore, MD, USA and Buffalo–Depew Station, NY, USA?

Southwest Airlines flies from Baltimore to Buffalo–Depew Station 5 times a day. Alternatively, you can take a train from Baltimore to Buffalo–Depew Station via New York Penn Station and Albany-Rensselaer Amtrak in around 11 h 23 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Baltimore to Buffalo
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$160 - $800
Flights from Baltimore to Rochester
Ave. Duration
1 h 11 min
When
Every day
Estimated price
$260 - $650
American Airlines
Website
aa.com
Flights from Reagan Washington to Buffalo
Ave. Duration
1 h 14 min
When
Every day
Estimated price
$120 - $600
Flights from Reagan Washington to Buffalo via Philadelphia
Ave. Duration
3 h 26 min
When
Saturday
Estimated price
$120 - $600
Flights from Philadelphia to Buffalo
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$200 - $1,100
United Airlines
Website
united.com
Flights from Washington Dulles to Buffalo
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$120 - $750
Flights from Philadelphia to Buffalo via Washington Dulles
Ave. Duration
3 h 32 min
When
Every day
Estimated price
$280 - $1,600
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Rochester Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
46 min
Frequency
Every 4 hours
Estimated price
$25 - $50
Website
amtrak.com
Coach Seat
$25 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from New York Penn Station to Albany-Rensselaer Amtrak
Ave. Duration
2 h 30 min
Frequency
Every 2 hours
Estimated price
$40 - $85
Website
amtrak.com
Coach Seat
$40 - $85
Business Seat
$65 - $110
Train from Albany-Rensselaer Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
4 h 50 min
Frequency
Every 4 hours
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Rochester to Buffalo
Ave. Duration
1 h 4 min
Frequency
Every 3 hours
Estimated price
$23 - $70
Website
viarail.ca
Escape
$23 - $35
Economy
$30 - $40
Economy Plus
$45 - $70
Business
$40 - $60
Business Plus/Sleeper
$75 - $110
Train from Albany to Buffalo
Ave. Duration
5 h 2 min
Frequency
Every 3 hours
Estimated price
$45 - $150
Website
viarail.ca
Escape
$45 - $65
Economy
$75 - $100
Economy Plus
$100 - $150
Business
$100 - $150
Business Plus/Sleeper
$190 - $270
Amtrak Acela Express
Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Baltimore Penn Station Amtrak to Washington Union Station Amtrak
Ave. Duration
40 min
Frequency
Hourly
Estimated price
$55 - $160
Website
amtrak.com
Business Seat
$55 - $150
First Class Seat
$120 - $160
Train from Baltimore Penn Station Amtrak to Philadelphia 30th Street Station Amtrak
Ave. Duration
1 h 3 min
Frequency
Hourly
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Train from Baltimore Penn Station Amtrak to New York Penn Station
Ave. Duration
2 h 20 min
Frequency
Hourly
Estimated price
$80 - $130
Website
amtrak.com
Coach
$80 - $130
Business Class
$120 - $200
First Class
$360 - $400
Metro Washington DC
Phone
202-637-7000
Website
wmata.com
Subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
Ave. Duration
37 min
Frequency
Every 15 minutes
Estimated price
$3 - $6
Schedules at
wmata.com
Bus operators

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.