There are 9 ways to get from Baltimore to Buffalo–Depew Station by plane, train, subway, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Baltimore to Buffalo  •  4 h 20 min

  1. Fly from Baltimore (BWI) to Buffalo (BUF) BWI - BUF

$124 - $604

Cheapest option

Bus Megabus  •  13 h 57 min

  1. Take the bus from White Marsh Mall Baltimore to Buffalo

$46 - $94

7 alternative options

Train to Reagan Washington, fly to Buffalo  •  5 h 3 min

  1. Take the train from Baltimore Penn Station to Washington Union Station
  2. Fly from Reagan Washington (DCA) to Buffalo (BUF) DCA - BUF

$176 - $634

Fly Baltimore to Rochester, train  •  5 h 38 min

  1. Fly from Baltimore (BWI) to Rochester (ROC) BWI - ROC
  2. Take the train from Rochester to Buffalo

$147 - $393

Train, subway to Washington Dulles, fly to Buffalo  •  5 h 56 min

  1. Take the train from Baltimore Penn Station to Washington Union Station
  2. Take the subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
  3. Fly from Washington Dulles (IAD) to Buffalo (BUF) IAD - BUF

$182 - $721

Train to Philadelphia, fly to Buffalo  •  5 h 43 min

  1. Take the train from Baltimore Penn Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$238 - $916

Train  •  11 h 3 min

  1. Take the train from Baltimore Penn Station to New York Penn Station Acela Express / ...
  2. Take the train from New York to Buffalo VIA Rail / ...

$172 - $504

Bus via Dubois, PA  •  15 h 21 min

  1. Take the bus from Baltimore Downtown, Md to Harrisburg, Pa
  2. Take the bus from Harrisburg to Dubois, PA
  3. Take the bus from Dubois, PA to Buffalo, NY

$87 - $175

Drive  •  6 h 52 min

  1. Drive from Baltimore to Buffalo–Depew Station 358.9 miles

$35 - $55

Questions & Answers

No, there is no direct bus from Baltimore to Buffalo–Depew Station. However, there are services departing from LOMBARD ST & CHARLES ST mb wb and arriving at Walden Ave & 2929 Walden via White Marsh Mall Baltimore, Ellicott St & North Division St and Galleria Drway & Green Parking Entrance. The journey, including transfers, takes approximately 13 h 57 min.

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No, there is no direct train from Baltimore station to Buffalo–Depew Station. However, there are services departing from Baltimore Penn Station and arriving at Buffalo via New York. The journey, including transfers, takes approximately 11 h 3 min.

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The distance between Baltimore and Buffalo–Depew Station is 275 miles. The road distance is 358.9 miles.

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The best way to get from Baltimore to Buffalo–Depew Station without a car is to train which takes 11 h 3 min and costs .

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It takes approximately 4 h 20 min to get from Baltimore to Buffalo–Depew Station, including transfers.

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Baltimore to Buffalo–Depew Station bus services, operated by Megabus, depart from White Marsh Mall Baltimore station.

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Baltimore to Buffalo–Depew Station train services, operated by Amtrak Acela Express, arrive at Baltimore Penn Station.

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The best way to get from Baltimore to Buffalo–Depew Station is to fly which takes 4 h 20 min and costs . Alternatively, you can train, which costs and takes 11 h 3 min, you could also bus, which costs and takes 13 h 57 min.

Mode details

The quickest flight from Baltimore Airport to Buffalo Airport is the direct flight which takes 1 h 5 min.

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Baltimore to Buffalo–Depew Station bus services, operated by Megabus, arrive at Buffalo station.

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Map of how to get from Baltimore to Buffalo–Depew Station.
Launch map view
  • Distance: 274.6 miles
  • Duration: 4 h 20 min

What companies run services between Baltimore, MD, USA and Buffalo–Depew Station, NY, USA?

Southwest Airlines flies from Baltimore to Buffalo–Depew Station every 4 hours. Alternatively, you can take a train from Baltimore to Buffalo–Depew Station via New York Penn Station and New York in around 11 h 3 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Baltimore to Buffalo
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$160 - $800
Flights from Baltimore to Rochester
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$260 - $650
American Airlines
Website
aa.com
Flights from Reagan Washington to Buffalo
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$120 - $600
Flights from Philadelphia to Buffalo
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$200 - $1,100
Flights from Philadelphia to Buffalo via Reagan Washington
Ave. Duration
3 h 14 min
When
Every day
Estimated price
$200 - $1,100
United Airlines
Website
united.com
Flights from Washington Dulles to Buffalo
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$120 - $750
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Baltimore Penn Station to Washington Union Station
Ave. Duration
40 min
Frequency
Hourly
Estimated price
$55 - $160
Website
amtrak.com
Business Seat
$55 - $150
First Class Seat
$120 - $160
Train from Baltimore Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Train from Baltimore Penn Station to New York Penn Station
Ave. Duration
2 h 12 min
Frequency
Hourly
Estimated price
$110 - $300
Website
amtrak.com
Business Seat
$110 - $230
First Class Seat
$190 - $300
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Rochester to Buffalo
Ave. Duration
1 h 9 min
Frequency
Every 3 hours
Estimated price
$24 - $70
Website
viarail.ca
Escape
$24 - $35
Economy
$30 - $45
Economy Plus
$50 - $70
Business
$40 - $60
Business Plus/Sleeper
$80 - $110
Train from New York to Buffalo
Ave. Duration
7 h 56 min
Frequency
Every 3 hours
Estimated price
$60 - $210
Website
viarail.ca
Escape
$60 - $85
Economy
$100 - $140
Economy Plus
$140 - $210
Business
$150 - $210
Business Plus/Sleeper
$270 - $380
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Rochester Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
1 h
Frequency
5 times a day
Estimated price
$25 - $50
Website
amtrak.com
Coach Seat
$25 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from New York Penn Station to Buffalo Depew Station Amtrak
Ave. Duration
7 h 42 min
Frequency
3 times a day
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Metro Washington DC
Phone
202-637-7000
Website
wmata.com
Subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
Ave. Duration
37 min
Frequency
Every 15 minutes
Estimated price
$3 - $6
Schedules at
wmata.com
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Baltimore Downtown, Md to Harrisburg, Pa
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Fullington Trailways
Phone
+1 800.942.8287
Website
fullingtontours.com
Bus from Harrisburg to Dubois, PA
Ave. Duration
4 h 45 min
Frequency
Once daily
Estimated price
$29 - $65
Schedules at
fullingtontours.com
Book at
fab.tdstickets.com
Bus from Dubois, PA to Buffalo, NY
Ave. Duration
4 h 40 min
Frequency
Once daily
Estimated price
$40 - $75
Schedules at
fullingtontours.com
Book at
fab.tdstickets.com

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More Questions & Answers

Baltimore to Buffalo–Depew Station train services, operated by VIA Rail, arrive at Buffalo station.

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Yes, the driving distance between Baltimore to Buffalo–Depew Station is 359 miles. It takes approximately 6 h 52 min to drive from Baltimore to Buffalo–Depew Station.

Get driving directions

Southwest Airlines offers flights from Baltimore Airport to Buffalo Airport.

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There are 130+ hotels available in Buffalo–Depew Station. Prices start at $65 USD per night.

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The best way to get from Baltimore to Baltimore Airport is to tram which takes 31 min and costs .

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