There are 8 ways to get from Avignon to Siena by train (TGV), bus, car, train, plane, or train (TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Avignon Tgv to Lyon Part DieuTgv
- Take the train from Lyon Part Dieu to Milano CentraleFr
- Take the train from Milano Centrale to Florence Santa Maria Novella
- Take the train from Firenze S.M.N. to SienaRe
12h 2m€103–312Bus via Genoa
cheapest- Take the bus from Avignon to Genoa1922
- Take the bus from Genoa to Siena516 / ...
14h 5m€44–111Bus
- Take the bus from Avignon to Marseille, Gare de Marseille-Saint-Charles
- Take the bus from Marseille - Saint-Charles Bus Station to Florence Villa Constanza Bus Station
- Take the bus from Florence Villa Constanza Bus Station to Siena443 / ...
12h 42m€55–115Drive 713 km
- Drive from Avignon to Siena713 km
7h 46m€110–159Train to Marseille Provence Airport, fly to Florence Peretola Airport, train
- Take the train from Avignon Tgv to Aix En Provence Tgv
- Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)MRS - FLR
- Take the train from Firenze S.M.N. to Siena
9h 18m€105–291Train via Ventimiglia
- Take the train from Avignon Tgv to Nice VilleTgv
- Take the train from Ventimiglia to Pisa CentraleIc
- Take the train from Pisa Centrale to EmpoliRe
- Take the train from Empoli to SienaRe
12h 45m€80–144Train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport, train
- Take the train from Avignon Tgv to Antibes
- Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)NCE - FLR
- Take the train from Firenze S.M.N. to Siena
9h 55m€126–267Train to Marseille Provence Airport, fly to Venice Marco Polo Airport, train
- Take the train from Avignon Tgv to Aix En Provence Tgv
- Fly from Marseille Provence Airport (MRS) to Venice Marco Polo Airport (VCE)MRS - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Siena
9h 57m€104–289
Avignon to Siena by train
Questions & Answers
The cheapest way to get from Avignon to Siena is to bus via Genoa which costs €40 - €120 and takes 14h 5m.
The fastest way to get from Avignon to Siena is to drive which takes 7h 46m and costs €110 - €160.
No, there is no direct bus from Avignon to Siena. However, there are services departing from Avignon and arriving at Siena via Marseille - Saint-Charles Bus Station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 12h 42m.
No, there is no direct train from Avignon to Siena. However, there are services departing from Avignon Tgv and arriving at Siena via Lyon Part Dieu, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 12h 2m.
The distance between Avignon and Siena is 1069 km. The road distance is 713 km.
The best way to get from Avignon to Siena without a car is to train which takes 12h 2m and costs €100 - €320.
It takes approximately 12h 2m to get from Avignon to Siena, including transfers.
Avignon to Siena bus services, operated by ALSA, depart from Avignon station.
Avignon to Siena train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon to Siena is to train which takes 12h 2m and costs €100 - €320. Alternatively, you can bus, which costs €55 - €120 and takes 12h 42m.
What companies run services between Avignon, France and Siena, Italy?
You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 12h 2m. Alternatively, you can take a bus from Avignon to Siena via Marseille - Saint-Charles Bus Station and Florence Villa Constanza Bus Station in around 12h 42m.
- Website
- lufthansa.com
Flights from Marseille Provence Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 52m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €75–250
- Website
- ita-airways.com
Flights from Nice Côte D'Azur International Airport to Florence Peretola Airport
- Ave. Duration
- 1h 10m
- When
- Monday and Friday
- Estimated price
- €80–180
Flights from Nice Côte D'Azur International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €85–140
- Website
- volotea.com
Flights from Marseille Provence Airport to Florence Peretola Airport via Lyon
- Ave. Duration
- 6h 45m
- When
- Monday
- Estimated price
- €95–230
Flights from Marseille Provence Airport to Venice Marco Polo Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–150
- Website
- aircorsica.com
Flights from Nice Côte D'Azur International Airport to Florence Peretola Airport
- Ave. Duration
- 1h 10m
- When
- Monday and Friday
- Estimated price
- €80–180
- Website
- swiss.com
Flights from Marseille Provence Airport to Venice Marco Polo Airport via Zurich
- Ave. Duration
- 3h 30m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €80–310
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- https://www.sncf-connect.com/en-en
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- €15–35
- Website
- https://www.sncf-connect.com/en-en
Train from Avignon Tgv to Nice Ville
- Ave. Duration
- 3h 28m
- Frequency
- 3 times a day
- Estimated price
- €40–75
- Website
- https://www.sncf-connect.com/en-en
Train from Avignon Tgv to Antibes
- Ave. Duration
- 3h 7m
- Frequency
- 3 times a day
- Estimated price
- €45–70
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €35–85
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €35–55
- Rail 1st Class
- €55–85
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 4 hours
- Estimated price
- €12–27
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €12–18
- Rail 1st Class
- €19–27
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- €17–60
- Website
- https://www.trenitalia.com/en.html
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 37m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- 3 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 14m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Florence Santa Maria Novella
- Ave. Duration
- 1h 55m
- Frequency
- Every 2 hours
- Estimated price
- €29–80
- Website
- https://www.italotreno.it/en
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once a week
- Estimated price
- €26–60
- Website
- https://www.italotreno.it/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- Twice daily
- Estimated price
- €7–10
- Website
- https://www.renfe.com/es/en
- Phone
- +352 24 89 24 89
- Website
- cfl.lu
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- Once daily
- Estimated price
- €18–28
- Website
- https://www.cfl.lu/en-gb
- 1st Class
- €18–28
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Ventimiglia to Pisa Centrale
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Schedules at
- trenitalia.com
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Avignon to Marseille, Gare de Marseille-Saint-Charles
- Ave. Duration
- 1h 15m
- Frequency
- 6 times a week
- Estimated price
- €9–20
- Website
- https://www.alsa.com/en/
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Marseille - Saint-Charles Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- €40–70
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–16
- Website
- https://www.flixbus.co.uk
Bus from Avignon to Genoa
- Ave. Duration
- 9h 5m
- Frequency
- Twice a week
- Estimated price
- €30–80
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Siena
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- €14–30
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- €6–26
- Website
- https://www.itabus.it/en/home
Bus from Genoa to Siena
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a week
- Estimated price
- €10–35
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–14
- Website
- https://marinobus.it/en/
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More Questions & Answers
Avignon to Siena bus services, operated by ALSA, arrive at Marseille, Gare de Marseille-Saint-Charles station.
Avignon to Siena train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Avignon to Siena is 713 km. It takes approximately 7h 46m to drive from Avignon to Siena.
Book your Avignon to Siena train tickets online with Omio.
Book your Avignon to Siena bus tickets online with Omio.
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