Rome2Rio

How to get fromAvignon to Sienaby train (TGV, Trenitalia), bus, car, train or plane

Find Transport to Siena

See all options

There are 8 ways to get from Avignon to Siena by train (TGV, Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 42m
    €106–303

  2. Bus via Genoa

    cheapest
    1. Take the bus from Avignon to Genoabus bus 1922
    2. Take the bus from Genoa to Sienabus bus 516 / ...
    14h 5m
    €40–105

  3. Bus

    1. Take the bus from Avignon to Marseille, Gare de Marseille-Saint-Charlesbus bus
    2. Take the bus from Marseille - Saint-Charles Bus Station to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    12h 42m
    €60–110

  4. Drive 713 km

    1. Drive from Avignon to Sienacar car 713 km
    7h 51m
    €111–161

  5. Train to Marseille Provence Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h
    €109–303

  6. Train via Ventimiglia

    1. Take the train from Avignon Tgv to Nice Villetrain train Tgv
    2. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    3. Take the train from Pisa Centrale to Empolitrain train Re
    4. Take the train from Empoli to Sienatrain train Re
    12h 13m
    €91–149

  7. Train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Cannestrain train
    2. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 23m
    €128–284

  8. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 16m
    €102–309

Avignon to Siena by train

Calendar14Weekly Trains
Duration11h 42mAverage Duration
Ticket€106Cheapest Price
See schedules

Questions & Answers

What companies run services between Avignon, France and Siena, Italy?

You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 11h 42m. Alternatively, you can take a bus from Avignon to Siena via Marseille - Saint-Charles Bus Station and Florence Villa Constanza Bus Station in around 12h 42m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers

Where to next?

Trips from Avignon

Trips to Siena

Popular routes