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How to get fromAvignon to Sienaby train (TGV, Trenitalia), bus, car, train, plane, or ferry

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There are 10 ways to get from Avignon to Siena by train (TGV, Trenitalia), bus, car, train, plane, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 36m
    €124–276
  2. Train to Marseille Provence Airport, fly to Bologna Guglielmo Marconi Airport, train

    cheapest
    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MRS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    7h 27m
    €67–236
  3. Bus

    1. Take the bus from Limbert/Remparts to La Beauvallebus bus 63
    2. Take the bus from Aix-en-Provence - Krypton Park & Ride to Sienabus bus BlaBlaCar Bus
    13h 20m
  4. Drive 712.7 km

    1. Drive from Avignon to Sienacar car 712.7 km
    7h 55m
    €112–162
  5. Train to Marseille Provence Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 11m
    €105–271
  6. Train via Ventimiglia

    1. Take the train from Avignon Centre to Marseille Saint-Charlestrain train C7 / ...
    2. Take the train from Marseille-Saint-Charles to Nice-Villetrain train
    3. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    4. Take the train from Pisa Centrale to Empolitrain train Re
    5. Take the train from Empoli to Sienatrain train Re
    14h 10m
    €108–213
  7. Bus via Genoa

    1. Take the bus from Avignon to Genoabus bus
    2. Take the bus from Genoa to Florencebus bus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    17h 11m
    €75–124
  8. Train, train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport

    1. Take the train from Avignon Tgv to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain train
    3. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 10m
  9. Train to Marseille Provence Airport, fly to Bastia - Poretta Airport, ferry, bus

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bastia - Poretta Airport (BIA)plane plane MRS - BIA
    3. Take the ferry from Port of Bastia to Port of Piombinoferry ferry
    4. Take the bus from Port of Piombino to Colonna San Marcobus bus
    11h 23m
    €136–348
  10. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 18m
    €88–276

Avignon to Siena by train

Calendar14Weekly Trains
Duration11h 36mAverage Duration
Ticket€124Cheapest Price
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Questions & Answers

What companies run services between Avignon, France and Siena, Italy?

You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 11h 36m. Alternatively, you can take a bus from Limbert/Remparts to Siena via La Beauvalle and Aix-en-Provence - Krypton Park & Ride in around 13h 20m.

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