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How to get fromAvignon to Sienaby train (TGV, Trenitalia), bus, car, train, or plane

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There are 9 ways to get from Avignon to Siena by train (TGV, Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 57m
    €124–276

  2. Bus

    cheapest
    1. Take the bus from Avignon to Aix-en-Provencebus bus N720 / ...
    2. Take the bus from Aix-en-Provence - Krypton Park & Ride to Sienabus bus BlaBlaCar Bus
    12h 55m
    €67–122

  3. Drive 712.8 km

    1. Drive from Avignon to Sienacar car 712.8 km
    7h 56m
    €111–160

  4. Train to Marseille Provence Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 37m
    €105–260

  5. Train via Ventimiglia

    1. Take the train from Avignon Tgv to Nice Villetrain train Tgv
    2. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    3. Take the train from Pisa Centrale to Empolitrain train Re
    4. Take the train from Empoli to Sienatrain train Re
    12h 47m
    €112–223

  6. Bus via Genoa

    1. Take the bus from Avignon to Genoabus bus 1922
    2. Take the bus from Genoa to Sienabus bus 516 / ...
    14h 5m
    €69–117

  7. Train to Marseille Provence Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MRS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    6h 56m
    €72–255

  8. Train, train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport

    1. Take the train from Avignon Tgv to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain train
    3. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 40m
    €172–389

  9. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 40m
    €90–305

Avignon to Siena by train

Calendar28Weekly Trains
Duration10h 57mAverage Duration
Ticket€124Cheapest Price
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Questions & Answers

Map of how to get from Avignon to Siena.ExpandLaunch map view
  • Distance: 1,068.6 km
  • Duration: 10h 57m

What companies run services between Avignon, France and Siena, Italy?

You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 10h 57m. Alternatively, you can take a bus from Avignon to Siena via Aix-en-Provence - Krypton Park & Ride in around 12h 55m.

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