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How to get fromAvignon to Sienaby train (TGV, Trenitalia), bus, car, train, or plane

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There are 9 ways to get from Avignon to Siena by train (TGV, Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 1m
    €124–277

  2. Bus

    cheapest
    1. Take the bus from Avignon - Le Pontet - Le Lac Stop to Marseille - Saint-Charles Bus Stationbus bus
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h 5m
    €58–102

  3. Drive 712.8 km

    1. Drive from Avignon to Sienacar car 712.8 km
    7h 55m
    €111–161

  4. Train to Marseille Provence Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 21m
    €100–250

  5. Train via Ventimiglia

    1. Take the train from Avignon Tgv to Nice Villetrain train Tgv
    2. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    3. Take the train from Pisa Centrale to Empolitrain train Re
    4. Take the train from Empoli to Sienatrain train Re
    12h 48m
    €111–213

  6. Bus via Genoa

    1. Take the bus from Limbert/Remparts to La Beauvallebus bus 63
    2. Take the bus from Aix-en-Provence - Krypton Park & Ride to Genoa - Via Fanti d'Italia Bus Stopbus bus
    3. Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Florence - Villa Costanzabus bus 18
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    14h 10m

  7. Train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Cannestrain train
    2. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 50m
    €161–332

  8. Train to Marseille Provence Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MRS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    6h 55m
    €78–255

  9. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 39m
    €95–315

Avignon to Siena by train

Calendar28Weekly Trains
Duration11h 1mAverage Duration
Ticket€124Cheapest Price
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Questions & Answers

Map of how to get from Avignon to Siena.ExpandLaunch map view
  • Distance: 1,068.6 km
  • Duration: 11h 1m

What companies run services between Avignon, France and Siena, Italy?

You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 11h 1m. Alternatively, you can take a bus from Avignon - Le Pontet - Le Lac Stop to Siena via Marseille, Gare de Marseille-Saint-Charles and Florence Villa Constanza Bus Station in around 13h 5m.

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