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How to get fromAvignon to Sienaby train (TGV, Trenitalia), bus, car, train, plane or ferry

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There are 10 ways to get from Avignon to Siena by train (TGV, Trenitalia), bus, car, train, plane, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 54m
    €127–290

  2. Bus

    cheapest
    1. Take the bus from Avignon – Bus Station to Marseille - Saint-Charles Bus Stationbus bus
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h 9m
    €51–100

  3. Bus via Nice Airport (NCE)

    1. Take the bus from Avignon – Bus Station to Nice - Airport Bus Station Terminal 1bus bus
    2. Take the bus from Nice Airport to Florencebus bus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    12h 37m
    €52–97

  4. Drive 713 km

    1. Drive from Avignon to Sienacar car 713 km
    7h 51m
    €112–161

  5. Train to Marseille Provence Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h
    €111–285

  6. Train via Ventimiglia

    1. Take the train from Avignon Tgv to Nice Villetrain train Tgv
    2. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    3. Take the train from Pisa Centrale to Empolitrain train Re
    4. Take the train from Empoli to Sienatrain train Re
    12h 41m
    €111–207

  7. Train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Antibestrain train
    2. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 49m
    €153–321

  8. Train to Marseille Provence Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MRS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    7h 29m
    €73–313

  9. Train to Marseille Provence Airport, fly to Bastia - Poretta Airport, ferry, bus

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bastia - Poretta Airport (BIA)plane plane MRS - BIA
    3. Take the ferry from Port of Bastia to Port of Piombinoferry ferry
    4. Take the bus from Port of Piombino to Colonna San Marcobus bus
    11h 2m
    €141–413

  10. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 14m
    €104–325

Avignon to Siena by train

Calendar14Weekly Trains
Duration11h 54mAverage Duration
Ticket€127Cheapest Price
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Questions & Answers

What companies run services between Avignon, France and Siena, Italy?

You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 11h 54m. Alternatively, you can take a bus from Avignon – Bus Station to Siena-Via Tozzi via Nice Airport, Florence, and Firenze Autostazione in around 12h 37m.

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