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How to get fromAvignon to Sienaby train (TGV, Trenitalia), bus, car, train, or plane

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There are 9 ways to get from Avignon to Siena by train (TGV, Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 45m
    €124–278

  2. Bus

    cheapest
    1. Take the bus from Avignon – Bus Station to Marseille - Saint-Charles Bus Stationbus bus
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h
    €57–103

  3. Bus via Nice Airport (NCE)

    1. Take the bus from Avignon – Bus Station to Nice - Airport Bus Station Terminal 1bus bus
    2. Take the bus from Nice Airport to Florencebus bus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    12h 36m
    €58–102

  4. Drive 712.7 km

    1. Drive from Avignon to Sienacar car 712.7 km
    7h 55m
    €113–164

  5. Train to Marseille Provence Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the train from Firenze Rifredi to Sienatrain train
    8h 24m
    €109–301

  6. Train via Ventimiglia

    1. Take the train from Avignon Tgv to Nice Villetrain train Tgv
    2. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    3. Take the train from Pisa Centrale to Empolitrain train Re
    4. Take the train from Empoli to Sienatrain train Re
    11h 42m
    €113–202

  7. Train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Antibestrain train
    2. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    3. Take the train from Firenze Rifredi to Sienatrain train
    8h 40m
    €174–342

  8. Train to Marseille Provence Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MRS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    6h 45m
    €67–280

  9. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 25m
    €88–282

Avignon to Siena by train

Calendar28Weekly Trains
Duration10h 45mAverage Duration
Ticket€124Cheapest Price
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Questions & Answers

Map of how to get from Avignon to Siena.ExpandLaunch map view
  • Distance: 1,068.6 km
  • Duration: 10h 45m

What companies run services between Avignon, France and Siena, Italy?

You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 10h 45m. Alternatively, you can take a bus from Avignon – Bus Station to Siena-Via Tozzi via Nice Airport, Florence, and Firenze Autostazione in around 12h 36m.

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