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How to get fromAvignon to Sienaby train, bus, car, plane, train (TGV, Trenitalia), or ferry

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There are 10 ways to get from Avignon to Siena by train, bus, car, plane, train (TGV, Trenitalia), or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus 131
    10h 59m
    €118–262

  2. Bus

    cheapest
    1. Take the bus from Avignon – Bus Station to Marseille - Saint-Charles Bus Stationbus bus
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h
    €56–97

  3. Drive 712.9 km

    1. Drive from Avignon to Sienacar car 712.9 km
    7h 56m
    €112–161

  4. Train to Marseille Provence Airport, fly to Florence Peretola Airport, bus

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    8h 18m
    €108–288

  5. Train

    1. Take the train from Avignon Tgv to Nice Villetrain train Tgv
    2. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    3. Take the train from Pisa Centrale to Empolitrain train Re
    4. Take the train from Empoli to Sienatrain train Re
    11h 58m
    €108–195

  6. Bus via Nice Airport (NCE)

    1. Take the bus from Avignon – Bus Station to Nice - Airport Bus Station Terminal 1bus bus
    2. Take the bus from Nice Airport to Pisabus bus
    3. Take the bus from Pisa Pietrasantina 2 - Park to Sienabus bus
    15h 35m
    €61–106

  7. Train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport, bus

    1. Take the train from Avignon Tgv to Antibestrain train
    2. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    8h 32m
    €157–314

  8. Train to Marseille Provence Airport, fly to Bologna Guglielmo Marconi Airport, train, bus

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MRS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    6h 42m
    €60–286

  9. Train to Marseille Provence Airport, fly to Bastia - Poretta Airport, ferry, bus

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bastia - Poretta Airport (BIA)plane plane MRS - BIA
    3. Take the ferry from Port of Bastia to Port of Piombinoferry ferry
    4. Take the bus from Port of Piombino to Colonna San Marcobus bus
    11h 3m
    €156–411

  10. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train, bus

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    8h 27m
    €82–288

Avignon to Siena by train and bus

Calendar14Weekly Services
Duration10h 59mAverage Duration
Ticket€118Cheapest Price
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Questions & Answers

What companies run services between Avignon, France and Siena, Italy?

You can take a bus from Avignon – Bus Station to Siena via Marseille, Gare de Marseille-Saint-Charles and Florence Villa Constanza Bus Station in around 13h. Alternatively, you can take a train from Avignon Tgv to Siena via Nice-Ville, Ventimiglia, Pisa Centrale, and Empoli in around 11h 58m.

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