There are 9 ways to get from Avignon to Sicily by train, plane, train (TGV, Trenitalia), car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Marseille Provence Airport, fly to Catania–Fontanarossa Airport
best- Take the train from Avignon Tgv to Aix En Provence Tgv
- Fly from Marseille Provence Airport (MRS) to Catania–Fontanarossa Airport (CTA)MRS - CTA
5h 11m€72–273Train to Marseille Provence Airport, fly to Palermo Airport
cheapest- Take the train from Avignon Tgv to Aix En Provence Tgv
- Fly from Marseille Provence Airport (MRS) to Palermo Airport (PMO)MRS - PMO
5h 34m€69–275Train via Milan
- Take the train from Avignon Tgv to Lyon Part DieuTgv
- Take the train from Lyon Part Dieu to Milano CentraleFr
- Take the train from Milano Centrale to Napoli Centrale
- Take the train from Napoli Centrale to Palermo CentraleIc
22h 30m€149–442Drive, car ferry
- Drive from Avignon to Port of Genoa
- Take the car ferry from Port of Genoa to Port of Palermo
25h 27m€136–241Bus
- Take the bus from Avignon to Marseille, Gare de Marseille-Saint-Charles
- Take the bus from Marseille, Gare de Marseille-Saint-Charles to Roma, Autostazione Tiburtina
- Take the bus from Roma, Autostazione Tiburtina to Palermo
29h 49m€81–281Train to Lyon–Saint Exupéry Airport, fly to Palermo Airport
- Take the train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Fly from Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO)LYS - PMO
5h 41m€79–401Train to Lyon–Saint Exupéry Airport, fly to Catania–Fontanarossa Airport
- Take the train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Fly from Lyon–Saint Exupéry Airport (LYS) to Catania–Fontanarossa Airport (CTA)LYS - CTA
5h 18m€92–429Bus, car ferry
- Take the bus from Avignon Le Pontet Bus Station to Genoa Piazza AcquaverdeUnion Ivkoni - Unibus 3574 / ...
- Take the car ferry from Port of Genoa to Port of Palermo
29h 48m€86–169Train
- Take the train from Avignon Centre to Marseille St CharlesTer
- Take the train from Marseille St Charles to Roma Termini
- Take the train from Roma Termini to Palermo CentraleIc
32h 11m€186–420
Avignon to Sicily by train
Questions & Answers
The cheapest way to get from Avignon to Sicily is to bus and car ferry which costs €85 - €170 and takes 29h 48m.
The fastest way to get from Avignon to Sicily is to train and fly which takes 5h 11m and costs €70 - €280.
No, there is no direct bus from Avignon to Sicily. However, there are services departing from Avignon and arriving at Piazza Boiardo via Marseille, Gare de Marseille-Saint-Charles, Roma, Autostazione Tiburtina and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 29h 49m.
No, there is no direct train from Avignon to Sicily. However, there are services departing from Avignon Tgv and arriving at Palermo Notarbartolo via Lyon Part Dieu, Milano Centrale, Napoli Centrale and Palermo Centrale. The journey, including transfers, takes approximately 22h 30m.
The distance between Avignon and Sicily is 1155 km.
The best way to get from Avignon to Sicily without a car is to train via Milan which takes 22h 30m and costs €140 - €450.
It takes approximately 5h 11m to get from Avignon to Sicily, including transfers.
Avignon to Sicily bus services, operated by ALSA, depart from Avignon station.
Avignon to Sicily train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon to Sicily is to train via Milan which takes 22h 30m and costs €140 - €450. Alternatively, you can bus, which costs €80 - €290 and takes 29h 49m.
What companies run services between Avignon, France and Sicily, Italy?
You can take a train from Avignon Tgv to Palermo Notarbartolo via Lyon Part Dieu, Milano Centrale, Napoli Centrale, and Palermo Centrale in around 22h 30m. Alternatively, you can take a bus from Avignon to Piazza Boiardo via Marseille, Gare de Marseille-Saint-Charles, Roma, Autostazione Tiburtina, Palermo, and Stazione Centrale Pensilina Esterna in around 29h 49m.
- Website
- ryanair.com
Flights from Marseille Provence Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 55m
- When
- Sunday
- Estimated price
- €50–160
Flights from Marseille Provence Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Sunday
- Estimated price
- €50–160
Flights from Marseille Provence Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 4h 20m
- When
- Monday, Friday, and Saturday
- Estimated price
- €50–160
Flights from Marseille Provence Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Friday, and Saturday
- Estimated price
- €50–180
- Website
- easyjet.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Wednesday
- Estimated price
- €45–240
Flights from Lyon–Saint Exupéry Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 5m
- When
- Tuesday
- Estimated price
- €80–180
- Website
- transavia.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Monday
- Estimated price
- €45–270
Flights from Lyon–Saint Exupéry Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 5m
- When
- Saturday
- Estimated price
- €45–270
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Friday
- Estimated price
- €40–220
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 22 min
- Frequency
- Hourly
- Estimated price
- €16–35
- Website
- https://www.sncf-connect.com/en-en
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €30–70
- Website
- https://www.sncf-connect.com/en-en
Train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Ave. Duration
- 50 min
- Frequency
- Once a week
- Estimated price
- €45–170
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 4 hours
- Estimated price
- €12–27
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €12–18
- Rail 1st Class
- €19–27
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €44
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Ave. Duration
- 51 min
- Frequency
- 5 times a day
- Estimated price
- €60–110
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Avignon Centre to Marseille St Charles
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- €26
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- 3 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- €13–45
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €30–45
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 37m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
Train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Ave. Duration
- 52 min
- Frequency
- 3 times a day
- Estimated price
- €21–70
- Website
- https://www.trenitalia.com/en.html
Train from Marseille St Charles to Roma Termini
- Ave. Duration
- 16h 2m
- Frequency
- Once a week
- Estimated price
- €120–280
- Website
- https://www.trenitalia.com/en.html
- Phone
- +352 24 89 24 89
- Website
- cfl.lu
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- Once daily
- Estimated price
- €18–28
- Website
- https://www.cfl.lu/en-gb
- 1st Class
- €18–28
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 23 min
- Frequency
- Once daily
- Estimated price
- €7–10
- Website
- https://www.renfe.com/es/en
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 14m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
Train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Ave. Duration
- 1h 6m
- Frequency
- Once a week
- Schedules at
- nomad.normandie.fr
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Napoli Centrale
- Ave. Duration
- 4h 33m
- Frequency
- Hourly
- Estimated price
- €50–140
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Napoli Centrale to Palermo Centrale
- Ave. Duration
- 8h 59m
- Frequency
- Once daily
- Estimated price
- €35–90
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 36m
- Frequency
- Once daily
- Estimated price
- €40–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Avignon to Marseille, Gare de Marseille-Saint-Charles
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- €9–40
- Website
- https://www.alsa.com/en/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Marseille, Gare de Marseille-Saint-Charles to Roma, Autostazione Tiburtina
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Estimated price
- €40–110
- Website
- https://www.flixbus.co.uk
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 13h 10m
- Frequency
- 6 times a week
- Estimated price
- €35–110
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- €30–50
- Schedules at
- autoservizisalemi.it
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 13h 15m
- Frequency
- 3 times a week
- Estimated price
- €70–130
- Website
- https://www.itabus.it/en/home
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Avignon Le Pontet Bus Station to Genoa Piazza Acquaverde
- Ave. Duration
- 7h
- Frequency
- 4 times a week
- Estimated price
- €19–27
- Website
- https://union-ivkoni.com/en
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €65–140
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
More Questions & Answers
Avignon to Sicily bus services, operated by ALSA, arrive at Marseille, Gare de Marseille-Saint-Charles station.
Avignon to Sicily train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Book your Avignon to Sicily train tickets online with Omio.
There are 266+ hotels available in Sicily.























































