There are 5 ways to get from Avignon to Issoire by train (TGV, Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Lyon
best- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Clermont Ferrandtrain Ter
5h 44m€49–116Bus
cheapest- Take the bus from Avignon - Pem to ALÈS - Gare Routièrebus 115
- Take the bus from Ales to Issoirebus Autocar
7h 34m€36–56Drive 284.5 km
- Drive from Avignon to Issoirecar 284.5 km
4h 2m€44–63Train
- Take the train from Avignon Centre to Nimestrain Ter
- Take the train from Nimes to Issoiretrain Ter
6h 4m€58–142Bus via Le Puy-en-Velay
- Take the bus from Avignon - Le Pontet - Le Lac Stop to Le Puy-en-Velaybus BlaBlaCar Bus
- Take the bus from Le Puy En Velay to Issoirebus Autocar
9h 23m€46–63
Avignon to Issoire by train
Questions & Answers
The cheapest way to get from Avignon to Issoire is to bus which costs €35 - €60 and takes 7h 34m.
The fastest way to get from Avignon to Issoire is to drive which takes 4h 2m and costs €40 - €65.
No, there is no direct bus from Avignon to Issoire. However, there are services departing from Avignon - Pem and arriving at Issoire via Ales. The journey, including transfers, takes approximately 7h 34m.
No, there is no direct train from Avignon to Issoire. However, there are services departing from Avignon Tgv and arriving at Issoire via Lyon Part Dieu and Clermont Ferrand. The journey, including transfers, takes approximately 5h 44m.
The distance between Avignon and Issoire is 480 km. The road distance is 284.5 km.
The best way to get from Avignon to Issoire without a car is to train via Lyon which takes 5h 44m and costs €45 - €120.
It takes approximately 5h 44m to get from Avignon to Issoire, including transfers.
Avignon to Issoire bus services, operated by liO – Région Occitanie (Gard services), depart from Avignon - Pem station.
Avignon to Issoire train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon to Issoire is to train via Lyon which takes 5h 44m and costs €45 - €120. Alternatively, you can bus, which costs €35 - €60 and takes 7h 34m.
What companies run services between Avignon, France and Issoire, Auvergne-Rhône-Alpes, France?
You can take a train from Avignon Tgv to Issoire via Lyon Part Dieu and Clermont Ferrand in around 5h 44m. Alternatively, you can take a bus from Avignon - Pem to Issoire via ALÈS - Gare Routière and Ales in around 7h 34m.
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €44
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Lyon Part Dieu to Clermont Ferrand
- Ave. Duration
- 2h 27m
- Frequency
- Every 4 hours
- Estimated price
- €27–45
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Avignon Centre to Nimes
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €17–45
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Nimes to Issoire
- Ave. Duration
- 4h 28m
- Frequency
- 3 times a day
- Estimated price
- €40–100
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- €17–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 14m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- 0806 800 350
- Website
- mestrajets.lio.laregion.fr
Bus from Avignon - Pem to ALÈS - Gare Routière
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- €2
- Schedules at
- mestrajets.lio.laregion.fr
- Phone
- 3635
- Website
- groupe-sncf.com
Bus from Ales to Issoire
- Ave. Duration
- 4h 49m
- Frequency
- Once daily
- Estimated price
- €35–55
- Website
- https://www.groupe-sncf.com/en
Bus from Le Puy En Velay to Issoire
- Ave. Duration
- 2h 3m
- Frequency
- 5 times a week
- Estimated price
- €16–23
- Website
- https://www.groupe-sncf.com/en
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Avignon - Le Pontet - Le Lac Stop to Le Puy-en-Velay
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a week
- Estimated price
- €29–45
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
More Questions & Answers
Avignon to Issoire bus services, operated by liO – Région Occitanie (Gard services), arrive at ALÈS - Gare Routière station.
Avignon to Issoire train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Avignon to Issoire is 284 km. It takes approximately 4h 2m to drive from Avignon to Issoire.
Book your Avignon to Issoire train tickets online with Omio.
There are 527+ hotels available in Issoire.























