There are 4 ways to get from Avignon to Issoire by train (TGV, Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Lyon
best- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Clermont Ferrandtrain Ter
5h 16m€68–142Bus
cheapest- Take the bus from Avignon to Clermont-Ferrandbus N1719 / ...
6h 46m€41–62Drive 284.5 km
- Drive from Avignon to Issoirecar 284.5 km
4h 1m€46–66Train
- Take the train from Avignon Centre to Nimestrain Ter
- Take the train from Nimes to Issoiretrain Ter
6h 3m€53–97
Avignon to Issoire by train
Comparing Your Travel Options
The cheapest way to get from Avignon to Issoire is to bus which costs €40 - €65 and takes 6h 46m.
The fastest way to get from Avignon to Issoire is to drive which takes 4h 1m and costs €45 - €70.
No, there is no direct bus from Avignon to Issoire. However, there are services departing from Avignon and arriving at Issoire via Maison de la Culture and Clermont Ferrand. The journey, including transfers, takes approximately 6h 46m.
No, there is no direct train from Avignon to Issoire. However, there are services departing from Avignon Tgv and arriving at Issoire via Lyon Part Dieu and Clermont Ferrand. The journey, including transfers, takes approximately 5h 16m.
The distance between Avignon and Issoire is 480 km. The road distance is 284.5 km.
The best way to get from Avignon to Issoire without a car is to train via Lyon which takes 5h 16m and costs €65 - €150.
It takes approximately 5h 16m to get from Avignon to Issoire, including transfers.
Avignon to Issoire bus services, operated by FlixBus, depart from Avignon station.
Avignon to Issoire train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon to Issoire is to train via Lyon which takes 5h 16m and costs €65 - €150. Alternatively, you can bus, which costs €40 - €65 and takes 6h 46m.
What companies run services between Avignon, France and Issoire, Auvergne-Rhône-Alpes, France?
You can take a train from Avignon Tgv to Issoire via Lyon Part Dieu and Clermont Ferrand in around 5h 16m. Alternatively, FlixBus operates a bus from Avignon to Clermont-Ferrand once daily. Tickets cost €30–50 and the journey takes 4h 50m.
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- €35–70
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Clermont Ferrand
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Oui.SNCF
Train from Avignon Centre to Nimes
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- Oui.SNCF
Train from Nimes to Issoire
- Ave. Duration
- 4h 28m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Twice daily
- Estimated price
- €27–40
- Website
- Trenitalia
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Twice a week
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Avignon Centre to Nimes
- Ave. Duration
- 35 min
- Frequency
- Every 3 hours
- Estimated price
- €12–18
- Website
- Zou! Lignes Express Régionales
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Avignon to Clermont-Ferrand
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- Flixbus
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Avignon to Issoire bus services, operated by FlixBus, arrive at Clermont-Ferrand station.
Avignon to Issoire train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Avignon to Issoire is 285 km. It takes approximately 4h 1m to drive from Avignon to Issoire.
Book your Avignon to Issoire train tickets online with Omio.
There are 613+ hotels available in Issoire.