There are 4 ways to get from Avignon to Issoire by train (TGV, Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Lyon
best- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Clermont Ferrandtrain Ter
5h 16m€73–144Bus
cheapest- Take the bus from Avignon to Lyonbus FlixBus N1135 / ...
- Take the bus from Lyon to Clermont-Ferrandbus FlixBus N1149 / ...
6h 17m€38–64Drive 284.5 km
- Drive from Avignon to Issoirecar 284.5 km
4h 2m€54–78Train
- Take the train from Avignon Centre to Nimestrain Ter
- Take the train from Nimes to Issoiretrain Ter
6h 5m€59–96
Avignon to Issoire by train
Comparing Your Travel Options
The cheapest way to get from Avignon to Issoire is to bus which costs €35 - €65 and takes 6h 17m.
The fastest way to get from Avignon to Issoire is to drive which takes 4h 2m and costs €50 - €80.
No, there is no direct bus from Avignon to Issoire. However, there are services departing from Avignon and arriving at Gare SNCF Parvis 1 via Lyon and Maison de la Culture. The journey, including transfers, takes approximately 6h 17m.
No, there is no direct train from Avignon to Issoire. However, there are services departing from Avignon Tgv and arriving at Issoire via Lyon Part Dieu and Clermont Ferrand. The journey, including transfers, takes approximately 5h 16m.
The distance between Avignon and Issoire is 480 km. The road distance is 284.5 km.
The best way to get from Avignon to Issoire without a car is to train via Lyon which takes 5h 16m and costs €70 - €150.
It takes approximately 5h 16m to get from Avignon to Issoire, including transfers.
Avignon to Issoire bus services, operated by FlixBus, depart from Avignon station.
Avignon to Issoire train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon to Issoire is to train via Lyon which takes 5h 16m and costs €70 - €150. Alternatively, you can bus, which costs €35 - €65 and takes 6h 17m.
What companies run services between Avignon, France and Issoire, Auvergne-Rhône-Alpes, France?
You can take a train from Avignon Tgv to Issoire via Lyon Part Dieu and Clermont Ferrand in around 5h 16m. Alternatively, you can take a bus from Avignon to Issoire via Lyon, Clermont-Ferrand, Maison de la Culture, Gare SNCF Parvis 1, and Clermont Ferrand in around 6h 17m.
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- €40–70
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Clermont Ferrand
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Oui.SNCF
Train from Avignon Centre to Nimes
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €9–15
- Website
- Oui.SNCF
Train from Nimes to Issoire
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- €50–80
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Twice daily
- Estimated price
- €27–40
- Website
- Trenitalia
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Twice a week
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Avignon Centre to Nimes
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- €12–17
- Website
- Zou! Lignes Express Régionales
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Avignon to Lyon
- Ave. Duration
- 2h 40m
- Frequency
- 5 times a day
- Estimated price
- €19–29
- Website
- Flixbus
Bus from Lyon to Clermont-Ferrand
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Avignon to Lyon
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- €17–29
- Website
- BlaBlaCar Bus
Bus from Lyon to Clermont-Ferrand
- Ave. Duration
- 2h 44m
- Frequency
- Hourly
- Estimated price
- €13–22
- Website
- BlaBlaCar Bus
Want to know more about travelling around France
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Booking & Getting There
Avignon to Issoire bus services, operated by FlixBus, arrive at Lyon station.
Avignon to Issoire train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Avignon to Issoire is 285 km. It takes approximately 4h 2m to drive from Avignon to Issoire.
Book your Avignon to Issoire train tickets online with Omio.
Book your Avignon to Issoire bus tickets online with Omio.
There are 613+ hotels available in Issoire.