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How to get fromAvignon to Issoireby train (TGV, Trenitalia), bus, car, or train

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There are 4 ways to get from Avignon to Issoire by train (TGV, Trenitalia), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Lyon

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Clermont Ferrandtrain train Ter
    5h 12m
    €69–162

  2. Bus

    cheapest
    1. Take the bus from Avignon to Lyonbus bus FlixBus N1135 / ...
    2. Take the bus from Lyon to Clermont-Ferrandbus bus FlixBus N1149 / ...
    6h 24m
    €37–72

  3. Drive 284.5 km

    1. Drive from Avignon to Issoirecar car 284.5 km
    4h 1m
    €45–64

  4. Train

    1. Take the train from Avignon Centre to Nimestrain train Ter
    2. Take the train from Nimes to Issoiretrain train Ter
    6h 4m
    €53–114

Avignon to Issoire by train

Calendar110Weekly Trains
Duration5h 12mAverage Duration
Ticket€69Cheapest Price
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Questions & Answers

Map of how to get from Avignon to Issoire.ExpandLaunch map view
  • Distance: 479.8 km
  • Duration: 5h 12m

What companies run services between Avignon, France and Issoire, Auvergne-Rhône-Alpes, France?

You can take a train from Avignon Tgv to Issoire via Lyon Part Dieu and Clermont Ferrand in around 5h 12m. Alternatively, you can take a bus from Avignon to Issoire via Lyon, Clermont-Ferrand, Maison de la Culture, Gare SNCF, and Clermont Ferrand in around 6h 24m.

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