There are 12 ways to get from Avignon to Brussels by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4 h 57 min

  1. Take the train from Avignon TGV to Bruxelles Midi Tgv / ...

$180 - $320

Cheapest option

Bus  •  14 h 2 min

  1. Take the bus from Avignon City Center to Paris City Center - Bercy Ouibus
  2. Take the bus from Paris City Center - Bercy to Brussels Schaerbeek - North Train station Ouibus

$35 - $49

10 alternative options

Train via Paris Gare De Lyon  •  6 h 8 min

  1. Take the train from Avignon Centre to Paris Gare de Lyon Tgv
  2. Take the train from Paris Nord to Bruxelles Midi Tha / ...

$216 - $265

Train Thalys  •  7 h 30 min

  1. Take the train from Avignon TGV to Antwerpen-Centraal Thalys
  2. Take the train from Anvers-Central to Bruxelles-Central Ic

$286 - $354

Drive  •  9 h 10 min

  1. Drive from Avignon to Brussels 596.5 miles

$120 - $190

Train to Marseille, fly to Brussels  •  5 h 5 min

  1. Take the train from Avignon TGV to Aix-en-Provence TGV
  2. Fly from Marseille (MRS) to Brussels (BRU) MRS - BRU

$74 - $296

Train to Marseille, fly to Charleroi  •  5 h 56 min

  1. Take the train from Avignon TGV to Aix-en-Provence TGV
  2. Fly from Marseille (MRS) to Charleroi (CRL) MRS - CRL

$61 - $275

Train to Marseille, fly to Lille Lesquin, train  •  5 h 44 min

  1. Take the train from Avignon TGV to Aix-en-Provence TGV
  2. Fly from Marseille (MRS) to Lille Lesquin (LIL) MRS - LIL
  3. Take the train from Lille Europe to Bruxelles Midi

$100 - $430

Train to Lyon, fly to Brussels  •  4 h 30 min

  1. Take the train from Avignon TGV to Lyon-St Exupery(TGV)
  2. Fly from Lyon (LYS) to Brussels (BRU) LYS - BRU

$86 - $273

Bus to Montpellier, fly to Charleroi  •  6 h 23 min

  1. Take the bus from Avignon City Center to Montpellier
  2. Fly from Montpellier (MPL) to Charleroi (CRL) MPL - CRL

$51 - $217

Train to Nimes, fly to Charleroi  •  6 h 52 min

  1. Take the train from Avignon Centre to Nîmes
  2. Fly from Nimes (FNI) to Charleroi (CRL) FNI - CRL

$67 - $258

Train to Geneva, fly to Brussels  •  6 h 55 min

  1. Take the train from Avignon TGV to Geneve
  2. Fly from Geneva (GVA) to Brussels (BRU) GVA - BRU

$127 - $295

Questions & Answers

The cheapest way to get from Avignon to Brussels is to bus which costs 30€ - 45€ and takes 14 h 2 min.

More details

The quickest way to get from Avignon to Brussels is to train and fly which costs 70€ - 240€ and takes 4 h 30 min.

More details

The distance between Avignon and Brussels is 768 km. The road distance is 954.4 km.

Get driving directions

The train from Avignon TGV to Bruxelles Midi takes 4 h 57 min including transfers and departs three times a day.

More details

No, there is no direct bus from Avignon to Brussels station. However, there are services departing from Avignon City Center and arriving at Brussels Schaerbeek - North Train station via Paris City Center - Bercy. The journey, including transfers, takes approximately 14 h 2 min.

More details

Yes, there is a direct train departing from Avignon TGV and arriving at Bruxelles Midi. Services depart three times a day, and operate Monday to Saturday. The journey takes approximately 4 h 57 min.

More details

What companies run services between Avignon, France and Brussels, Belgium?

TGV operates a train from Avignon to Brussels 3 times a day. Tickets cost $180 - $210 and the journey takes 4 h 57 min. Thalys also services this route once a week. Alternatively, you can take a bus from Avignon to Brussels via Paris City Center - Bercy in around 14 h 2 min.

Airlines
Air France
Website
airfrance.com
Flights from Marseille to Brussels via Lyon
Ave. Duration
3 h 22 min
When
Monday to Friday
Estimated price
$220 - $700
Flights from Marseille to Brussels via Calvi
Ave. Duration
4 h 30 min
When
Saturday
Estimated price
$200 - $750
Flights from Marseille to Lille Lesquin
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Lyon
Ave. Duration
3 h 17 min
When
Monday to Friday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Toulouse
Ave. Duration
3 h 50 min
When
Tuesday and Thursday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Nantes
Ave. Duration
4 h
When
Thursday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Calvi
Ave. Duration
3 h 55 min
When
Sunday
Estimated price
$95 - $550
Flights from Lyon to Brussels
Ave. Duration
1 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Hop!
Website
hop.com
Flights from Marseille to Brussels via Lyon
Ave. Duration
3 h 22 min
When
Monday to Friday
Estimated price
$220 - $700
Flights from Marseille to Lille Lesquin
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Lyon
Ave. Duration
3 h 17 min
When
Monday to Friday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Toulouse
Ave. Duration
3 h 50 min
When
Tuesday and Thursday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Nantes
Ave. Duration
4 h
When
Thursday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Calvi
Ave. Duration
3 h 55 min
When
Sunday
Estimated price
$95 - $550
Flights from Lyon to Brussels
Ave. Duration
1 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Brussels Airlines
Website
brusselsairlines.com
Flights from Marseille to Brussels
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$70 - $550
Flights from Lyon to Brussels
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$60 - $370
Flights from Geneva to Brussels
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$60 - $460
Lufthansa
Website
lufthansa.com
Flights from Marseille to Brussels via Frankfurt
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$180 - $800
Flights from Marseille to Brussels via Munich
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$180 - $800
Flights from Lyon to Brussels via Frankfurt
Ave. Duration
3 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Lyon to Brussels via Munich
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$160 - $600
Flights from Geneva to Brussels via Frankfurt
Ave. Duration
3 h 21 min
When
Every day
Estimated price
$150 - $650
Flights from Geneva to Brussels via Munich
Ave. Duration
3 h 20 min
When
Every day
Estimated price
$150 - $650
Swiss
Website
swiss.com
Flights from Marseille to Brussels via Zurich
Ave. Duration
3 h 45 min
When
Tuesday and Thursday
Estimated price
$70 - $420
Flights from Geneva to Brussels
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$60 - $460
Flights from Geneva to Brussels via Zurich
Ave. Duration
2 h 55 min
When
Every day
Estimated price
$110 - $400
Ryanair
Website
ryanair.com
Flights from Marseille to Charleroi
Ave. Duration
1 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Saturday and Sunday
Estimated price
$35 - $350
Flights from Marseille to Lille Lesquin
Ave. Duration
1 h 35 min
When
Monday to Saturday
Estimated price
$45 - $330
Flights from Montpellier to Charleroi
Ave. Duration
1 h 45 min
When
Tuesday, Wednesday, Thursday, Saturday and Sunday
Estimated price
$35 - $290
Flights from Nimes to Charleroi
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$35 - $400
easyJet
Website
easyjet.com
Flights from Geneva to Brussels
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$45 - $290
British Airways
Website
britishairways.com
Flights from Marseille to Brussels via London Heathrow
Ave. Duration
4 h 15 min
When
Saturday
Estimated price
$160 - $800
Air Corsica
Website
aircorsica.com
Flights from Marseille to Charleroi via Bastia
Ave. Duration
3 h 50 min
When
Tuesday, Wednesday, Thursday, Saturday and Sunday
Estimated price
$190 - $1,300
Train operators
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Avignon TGV to Bruxelles Midi
Ave. Duration
4 h 57 min
Frequency
3 times a day
Estimated price
$180 - $210
Website
en.oui.sncf
2nd Class
$180 - $210
1st Class
$240 - $360
Train from Avignon Centre to Paris Gare de Lyon
Ave. Duration
3 h 53 min
Frequency
3 times a day
Estimated price
$120 - $140
Website
en.oui.sncf
2nd Class
$120 - $140
1st Class
$170 - $250
Train from Avignon TGV to Aix-en-Provence TGV
Ave. Duration
26 min
Frequency
Hourly
Estimated price
$20 - $25
Website
en.oui.sncf
2nd Class
$20 - $25
1st Class
$35 - $38
Train from Lille Europe to Bruxelles Midi
Ave. Duration
34 min
Frequency
Every 2 hours
Estimated price
$26 - $31
Website
en.oui.sncf
2nd Class
$26 - $31
1st Class
$44 - $48
Train from Avignon TGV to Lyon-St Exupery(TGV)
Ave. Duration
51 min
Frequency
Once daily
Estimated price
$45 - $55
Website
en.oui.sncf
2nd Class
$45 - $55
1st Class
$70 - $90
Train from Avignon TGV to Geneve
Ave. Duration
2 h 50 min
Frequency
Once daily
Estimated price
$75 - $90
Website
en.oui.sncf
2nd Class
$75 - $90
1st Class
$100 - $150
Thalys
Website
thalys.com
Train from Avignon TGV to Brussel-Zuid/Midi
Ave. Duration
4 h 38 min
Frequency
Once a week
Estimated price
$260 - $320
Website
thalys.com
2nd Class
$260 - $320
1st Class
$330 - $470
Train from Paris Nord to Bruxelles Midi
Ave. Duration
1 h 28 min
Frequency
Hourly
Estimated price
$85 - $120
Website
thalys.com
2nd Class
$85 - $120
1st Class
$120 - $160
Train from Avignon TGV to Antwerpen-Centraal
Ave. Duration
5 h 21 min
Frequency
Once a week
Estimated price
$270 - $330
Website
thalys.com
2nd Class
$270 - $330
1st Class
$340 - $480
Train from Avignon TGV to Aix-en-Provence TGV
Ave. Duration
20 min
Frequency
Once a week
Estimated price
$25 - $45
Website
thalys.com
2nd Class
$25 - $45
1st Class
$40 - $55
Train from Lille Europe to Brussel-Zuid/Midi
Ave. Duration
36 min
Frequency
Twice daily
Estimated price
$30 - $55
Website
thalys.com
2nd Class
$30 - $55
1st Class
$55 - $70
Belgian Railways (NMBS/SNCB)
Phone
+32 2 528 28 28
Website
b-rail.be
Train from Anvers-Central to Bruxelles-Central
Ave. Duration
39 min
Frequency
Hourly
Estimated price
$7 - $11
Website
belgianrail.be
Book at
eurail.com
2nd Class
$7 - $11
1st Class
$11 - $16
SNCF
Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Avignon TGV to Aix-en-Provence TGV
Ave. Duration
25 min
Frequency
Once daily
Estimated price
$17 - $25
Website
en.oui.sncf
2nd Class
$17 - $25
1st Class
$22 - $35
Train from Avignon Centre to Nîmes
Ave. Duration
31 min
Frequency
Hourly
Estimated price
$14 - $21
Website
en.oui.sncf
2nd Class
$14 - $21
1st Class
$18 - $28
Eurostar
Rome2rio's guide to Eurostar
Contact Details
Website
eurostar.com
Train from Lille Europe Eurostar to Bruxelles-Midi Eurostar
Ave. Duration
35 min
Frequency
Every 3 hours
Estimated price
$30 - $55
Website
eurostar.com
Standard
$30 - $55
Premier
$66 - $68
Bus operators
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Avignon City Center to Paris City Center - Bercy
Ave. Duration
9 h 45 min
Frequency
Every 10 minutes
Estimated price
$24 - $35
Website
Ouibus
Bus from Paris City Center - Bercy to Brussels Schaerbeek - North Train station
Ave. Duration
4 h 15 min
Frequency
Every 5 minutes
Estimated price
$11 - $16
Website
Ouibus
Bus from Avignon City Center to Montpellier
Ave. Duration
1 h 5 min
Frequency
Every 20 minutes
Estimated price
$3 - $6
Website
Ouibus

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