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There are 9 ways to get from Avignon to Brussels by train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4h 50m

  1. Take the train from Avignon TGV to Bruxelles Midi Tgv / ...

$180 - $320

Cheapest option

Train to Marseille, fly to Charleroi  •  5h 56m

  1. Take the train from Avignon TGV to Aix-en-Provence TGV
  2. Fly from Marseille (MRS) to Charleroi (CRL) MRS - CRL

$62 - $275

7 alternative options

Train via Paris Gare De Lyon  •  6h 31m

  1. Take the train from Avignon Centre to Paris Gare de Lyon Tgv
  2. Take the train from Paris-Nord to Brussel-Zuid/Midi Thalys

$215 - $264

Drive  •  9h 10m

  1. Drive from Avignon to Brussels 596.5 miles

$120 - $190

Train to Marseille, fly to Brussels  •  4h 58m

  1. Take the train from Avignon TGV to Aix-en-Provence TGV
  2. Fly from Marseille (MRS) to Brussels (BRU) MRS - BRU

$74 - $296

Train to Lyon, fly to Brussels  •  4h 33m

  1. Take the train from Avignon TGV to Lyon-St Exupery(TGV)
  2. Fly from Lyon (LYS) to Brussels (BRU) LYS - BRU

$85 - $273

Train to Marseille, fly to Lille Lesquin, train  •  6h 8m

  1. Take the train from Avignon TGV to Aix-en-Provence TGV
  2. Fly from Marseille (MRS) to Lille Lesquin (LIL) MRS - LIL
  3. Take the train from Lille Europe Eurostar to Bruxelles-Midi Eurostar

$105 - $435

Train to Geneva, fly to Brussels  •  6h 53m

  1. Take the train from Avignon TGV to Genève
  2. Fly from Geneva (GVA) to Brussels (BRU) GVA - BRU

$126 - $294

Train to Nimes, fly to Charleroi  •  6h 52m

  1. Take the train from Avignon Centre to Nîmes
  2. Fly from Nimes (FNI) to Charleroi (CRL) FNI - CRL

$66 - $258

Questions & Answers

The cheapest way to get from Avignon to Brussels is to train and fly which costs 50€ - 240€ and takes 5h 56m.

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The quickest way to get from Avignon to Brussels is to train and fly which costs 70€ - 240€ and takes 4h 33m.

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Yes, there is a direct train departing from Avignon TGV and arriving at Bruxelles Midi. Services depart twice daily, and operate Wednesday, Thursday, Friday and Saturday. The journey takes approximately 4h 50m.

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The distance between Avignon and Brussels is 768 km. The road distance is 954.4 km.

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The best way to get from Avignon to Brussels without a car is to train which takes 4h 50m and costs 160€ - 280€.

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The train from Avignon TGV to Bruxelles Midi takes 4h 50m including transfers and departs twice daily.

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Avignon to Brussels train services, operated by inOui TGV, depart from Avignon TGV station.

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The quickest flight from Marseille Airport to Brussels Airport is the direct flight which takes 1h 40m.

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Avignon to Brussels train services, operated by inOui TGV, arrive at Bruxelles Midi station.

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Yes, the driving distance between Avignon to Brussels is 954 km. It takes approximately 9h 10m to drive from Avignon to Brussels.

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Map of how to get from Avignon to Brussels.
Launch map view
  • Distance: 480.2 miles
  • Duration: 4h 50m

What companies run services between Avignon, France and Brussels, Belgium?

inOui TGV operates a train from Avignon to Brussels once daily. Tickets cost $180 - $200 and the journey takes 4h 50m. Thalys also services this route once a week.

Airlines
Air France
Website
airfrance.com
Flights from Marseille to Brussels via Lyon
Ave. Duration
3h 15m
When
Monday to Friday
Estimated price
$210 - $750
Flights from Lyon to Brussels
Ave. Duration
1h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $420
Flights from Lyon to Brussels via Amsterdam Schiphol
Ave. Duration
3h 20m
When
Monday to Saturday
Estimated price
$140 - $550
Flights from Marseille to Lille Lesquin
Ave. Duration
1h 35m
When
Every day
Estimated price
$90 - $550
Flights from Marseille to Lille Lesquin via Lyon
Ave. Duration
3h 7m
When
Monday to Friday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Ajaccio
Ave. Duration
3h 50m
When
Sunday
Estimated price
$90 - $550
Flights from Marseille to Lille Lesquin via Nantes
Ave. Duration
4h 10m
When
Sunday
Estimated price
$90 - $550
Hop!
Website
hop.com
Flights from Marseille to Brussels via Lyon
Ave. Duration
3h 17m
When
Monday to Friday
Estimated price
$220 - $700
Flights from Lyon to Brussels
Ave. Duration
1h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Marseille to Lille Lesquin
Ave. Duration
1h 35m
When
Every day
Estimated price
$90 - $550
Flights from Marseille to Lille Lesquin via Lyon
Ave. Duration
3h 7m
When
Monday to Friday
Estimated price
$95 - $550
Flights from Marseille to Lille Lesquin via Ajaccio
Ave. Duration
3h 50m
When
Sunday
Estimated price
$90 - $550
Flights from Marseille to Lille Lesquin via Nantes
Ave. Duration
4h 10m
When
Sunday
Estimated price
$90 - $550
Brussels Airlines
Website
brusselsairlines.com
Flights from Marseille to Brussels
Ave. Duration
1h 42m
When
Every day
Estimated price
$70 - $550
Flights from Lyon to Brussels
Ave. Duration
1h 21m
When
Every day
Estimated price
$60 - $370
Flights from Geneva to Brussels
Ave. Duration
1h 17m
When
Every day
Estimated price
$60 - $460
Swiss
Website
swiss.com
Flights from Geneva to Brussels
Ave. Duration
1h 17m
When
Every day
Estimated price
$60 - $460
Flights from Geneva to Brussels via Zurich
Ave. Duration
3h 15m
When
Every day
Estimated price
$110 - $400
Lufthansa
Website
lufthansa.com
Flights from Marseille to Brussels via Frankfurt
Ave. Duration
3h 40m
When
Every day
Estimated price
$180 - $800
Flights from Marseille to Brussels via Munich
Ave. Duration
3h 50m
When
Monday to Friday
Estimated price
$180 - $800
Flights from Lyon to Brussels via Frankfurt
Ave. Duration
3h 35m
When
Every day
Estimated price
$160 - $600
Flights from Geneva to Brussels via Frankfurt
Ave. Duration
3h 17m
When
Every day
Estimated price
$150 - $650
Flights from Geneva to Brussels via Munich
Ave. Duration
3h 30m
When
Every day
Estimated price
$150 - $650
Ryanair
Website
ryanair.com
Flights from Marseille to Charleroi
Ave. Duration
1h 45m
When
Every day
Estimated price
$35 - $350
Flights from Marseille to Lille Lesquin
Ave. Duration
1h 35m
When
Monday, Wednesday, Friday and Sunday
Estimated price
$45 - $330
Flights from Nimes to Charleroi
Ave. Duration
1h 40m
When
Monday, Wednesday, Friday and Sunday
Estimated price
$35 - $400
easyJet
Website
easyjet.com
Flights from Geneva to Brussels
Ave. Duration
1h 18m
When
Every day
Estimated price
$45 - $290
KLM
Website
klm.com
Flights from Lyon to Brussels via Amsterdam Schiphol
Ave. Duration
3h 20m
When
Monday to Saturday
Estimated price
$140 - $550
Train operators
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Avignon TGV to Bruxelles Midi
Ave. Duration
4h 50m
Frequency
Once daily
Estimated price
$180 - $200
Website
en.oui.sncf
2nd Class
$180 - $200
1st Class
$240 - $360
Train from Avignon Centre to Paris Gare de Lyon
Ave. Duration
3h 58m
Frequency
4 times a day
Estimated price
$120 - $140
Website
en.oui.sncf
2nd Class
$120 - $140
1st Class
$170 - $250
Train from Avignon TGV to Aix-en-Provence TGV
Ave. Duration
25m
Frequency
Hourly
Estimated price
$20 - $25
Website
en.oui.sncf
2nd Class
$20 - $25
1st Class
$35 - $38
Train from Avignon TGV to Lyon-St Exupery(TGV)
Ave. Duration
51m
Frequency
6 times a week
Estimated price
$45 - $55
Website
en.oui.sncf
2nd Class
$45 - $55
1st Class
$65 - $90
Train from Lille Europe to Bruxelles Midi
Ave. Duration
35m
Frequency
Every 4 hours
Estimated price
$25 - $31
Website
en.oui.sncf
2nd Class
$25 - $31
1st Class
$44 - $47
Train from Avignon TGV to Genève
Ave. Duration
2h 50m
Frequency
3 times a week
Estimated price
$75 - $85
Website
en.oui.sncf
2nd Class
$75 - $85
1st Class
$100 - $150
Thalys
Phone
+32 70 66 77 88
Website
thalys.com
Train from Avignon TGV to Brussel-Zuid/Midi
Ave. Duration
4h 38m
Frequency
Once a week
Estimated price
$260 - $320
Website
thalys.com
2nd Class
$260 - $320
1st Class
$330 - $460
Train from Paris-Nord to Brussel-Zuid/Midi
Ave. Duration
1h 22m
Frequency
Every 2 hours
Estimated price
$85 - $120
Website
thalys.com
2nd Class
$85 - $120
1st Class
$120 - $160
Train from Avignon TGV to Aix-en-Provence TGV
Ave. Duration
25m
Frequency
Once a week
Estimated price
$25 - $45
Website
thalys.com
2nd Class
$25 - $45
1st Class
$40 - $55
SNCF

Loosely translated as the French National Railway Corporation, the SNCF is France’s state-owned railway company. It covers the country’s extensive rail network, as well as the TGV and Thalys, France’s two high-speed railway networks. With over 14,000 trains operating daily, it is a fast and efficient way of travelling around the country. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Avignon TGV to Aix-en-Provence TGV
Ave. Duration
25m
Frequency
4 times a week
Estimated price
$17 - $25
Website
en.oui.sncf
2nd Class
$17 - $25
1st Class
$22 - $35
Train from Avignon Centre to Nîmes
Ave. Duration
31m
Frequency
Hourly
Estimated price
$14 - $21
Website
en.oui.sncf
2nd Class
$14 - $21
1st Class
$18 - $27
Eurostar

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Air France, Brussels Airlines, Hop! and Lufthansa offer flights from Marseille Airport to Brussels Airport.

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Book your Avignon to Brussels train tickets online with Rome2rio.

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There are 1037+ hotels available in Brussels. Prices start at $69 USD per night.

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