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How to get fromAvignon to Brusselsby train, bus, car, plane, or train (TGV)

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There are 11 ways to get from Avignon to Brussels by train, bus, car, plane, or train (TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon TGV to Bruxelles-Miditrain train Trn
    5h 20m
    €160–330

  2. Train to Nîmes-Alès-Camargue-Cévennes Airport, fly to Brussels South Charleroi Airport, train

    cheapest
    1. Take the train from Avignon Centre to Nimestrain train
    2. Fly from Nîmes-Alès-Camargue-Cévennes Airport (FNI) to Brussels South Charleroi Airport (CRL)plane plane FNI - CRL
    3. Take the train from Charleroi-Central to Bruxelles-Centraltrain train
    7h 22m
    €72–399

  3. Bus

    1. Take the bus from Avignon to Lillebus bus 1685
    2. Take the bus from Lille - Europe Train Station to Brussels - Midi Train Stationbus bus BlaBlaCar Bus
    14h 23m
    €82–136

  4. Drive 889.5 km

    1. Drive from Avignon to Brusselscar car 889.5 km
    9h 40m
    €137–198

  5. Train to Marseille Provence Airport, fly to Brussels Airport

    1. Take the train from Avignon Centre to Vitrolles Aeroport Marseilletrain train
    2. Fly from Marseille Provence Airport (MRS) to Brussels Airport (BRU)plane plane MRS - BRU
    5h 22m
    €88–243

  6. Train via Avignon Centre (TGV)

    1. Take the train from Avignon Tgv to Brussel-Zuid / Bruxelles-Miditrain train Tgv
    6h 13m
    €191–322

  7. Train to Lyon–Saint Exupéry Airport, fly to Brussels Airport

    1. Take the train from Avignon Tgv to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Brussels Airport (BRU)plane plane LYS - BRU
    4h 33m
    €109–306

  8. Train to Marseille Provence Airport, fly to Brussels South Charleroi Airport, train

    1. Take the train from Avignon Centre to Vitrolles Aeroport Marseilletrain train
    2. Fly from Marseille Provence Airport (MRS) to Brussels South Charleroi Airport (CRL)plane plane MRS - CRL
    3. Take the train from Charleroi-Central to Bruxelles-Centraltrain train
    6h 40m
    €78–281

  9. Train to Marseille Provence Airport, fly to Paris Charles De Gaulle Airport, train

    1. Take the train from Avignon Centre to Vitrolles Aeroport Marseilletrain train
    2. Fly from Marseille Provence Airport (MRS) to Paris Charles De Gaulle Airport (CDG)plane plane MRS - CDG
    3. Take the train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Miditrain train
    6h 10m
    €171–448

  10. Train to Marseille Provence Airport, fly to Lille-Lesquin Airport, train

    1. Take the train from Avignon Centre to Vitrolles Aeroport Marseilletrain train
    2. Fly from Marseille Provence Airport (MRS) to Lille-Lesquin Airport (LIL)plane plane MRS - LIL
    3. Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain train
    6h 2m
    €89–325

  11. Train, train to Nice Côte D'Azur International Airport, fly to Brussels Airport

    1. Take the train from Avignon Tgv to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain train
    3. Fly from Nice Côte D'Azur International Airport (NCE) to Brussels Airport (BRU)plane plane NCE - BRU
    8h 8m
    €141–383

Avignon to Brussels by train

Calendar2Weekly Trains
Duration5h 20mAverage Duration
Ticket€160Cheapest Price
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Map of how to get from Avignon to Brussels.ExpandLaunch map view
  • Distance: 967.4 km
  • Duration: 5h 20m

What companies run services between Avignon, France and Brussels, Belgium?

Belgian Railways (NMBS/SNCB) operates a train from Avignon TGV to Bruxelles-Midi twice a week. Tickets cost €160–330 and the journey takes 5h 20m. Alternatively, you can take a bus from Avignon to Brussels - Midi Train Station via Lille and Lille - Europe Train Station in around 14h 23m.

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