From Atlanta airport fly to Knoxville airport then taxi to Knoxville. 1 h 9 min $422. From Airport Station subway to Atlanta GA then Megabus to Knoxville. 5 h 24 min $30. From Airport Station subway to Atlanta, GA then bus to Knoxville, TN. 6 h 32 min $47. From Atlanta Airport (ATL) drive to Knoxville. 3 h 44 min $25.