There are 12 ways to get from Asti to Isernia by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Rome
best- Take the train from Asti to Milan Rogoredotrain
- Take the train from Milan Rogoredo to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
8h 4m€67–186Train, train to Milano Malpensa Airport, fly to Abruzzo Airport, bus
cheapest- Take the train from Asti to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane MXP - PSR
- Take the bus from Pescara to Iserniabus
10h€48–187Bus
- Take the bus from Asti - Asti Ovest to Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
11h 58m€64–89Drive 769 km
- Drive from Asti to Iserniacar 769 km
7h 23m€119–171Train to Turin Caselle Airport, fly to Naples Airport, train
- Take the train from Asti to Torino Aeroporto Di Caselletrain
- Fly from Turin Caselle Airport (TRN) to Naples Airport (NAP)plane TRN - NAP
- Take the train from Napoli Centrale to Iserniatrain
7h 28m€58–151Train (Trenitalia)
- Take the train from Asti to Cassinotrain Ic
- Take the train from Cassino to Iserniatrain Re
10h 37m€49–64Train, bus
- Take the train from Asti to Genova P.Za Principetrain
- Take the bus from Genoa to Florence Villa Constanza Bus Stationbus 510 / ...
- Take the bus from Florence Villa Constanza Bus Station to Iserniabus 433
16h 8m€64–118Train to Milan Linate Airport, fly to Naples Airport, train
- Take the train from Asti to Milano Lambratetrain
- Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane LIN - NAP
- Take the train from Napoli Centrale to Iserniatrain
7h 41m€61–166Train to Genoa Cristoforo Colombo Airport, fly to Naples Airport, train
- Take the train from Asti to Genova P.Za Principetrain
- Fly from Genoa Cristoforo Colombo Airport (GOA) to Naples Airport (NAP)plane GOA - NAP
- Take the train from Napoli Centrale to Iserniatrain
8h 5m€67–170Train to Genoa Cristoforo Colombo Airport, fly to Fiumicino International Airport, train
- Take the train from Asti to Genova P.Za Principetrain
- Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane GOA - FCO
- Take the train from Roma Termini to Iserniatrain
8h 15m€78–244Train, train to Milano Malpensa Airport, fly to Naples Airport
- Take the train from Asti to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane MXP - NAP
- Take the train from Napoli Centrale to Iserniatrain
8h 43m€50–167Train to Turin Caselle Airport, fly to Abruzzo Airport, bus
- Take the train from Asti to Torino Aeroporto Di Caselletrain
- Fly from Turin Caselle Airport (TRN) to Abruzzo Airport (PSR)plane TRN - PSR
- Take the bus from Pescara to Iserniabus
8h 40m€52–281
Asti to Isernia by train
Questions & Answers
The cheapest way to get from Asti to Isernia is to train which costs €45 - €65 and takes 10h 37m.
The fastest way to get from Asti to Isernia is to drive which takes 7h 23m and costs €110 - €180.
No, there is no direct bus from Asti to Isernia. However, there are services departing from Asti - Asti Ovest and arriving at Isernia via Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 11h 58m.
No, there is no direct train from Asti to Isernia. However, there are services departing from Asti and arriving at Isernia via Milan Rogoredo and Roma Termini. The journey, including transfers, takes approximately 8h 4m.
The distance between Asti and Isernia is 866 km. The road distance is 769 km.
The best way to get from Asti to Isernia without a car is to train via Rome which takes 8h 4m and costs €65 - €190.
It takes approximately 8h 4m to get from Asti to Isernia, including transfers.
Asti to Isernia bus services, operated by Gruppo Di Maio, depart from Asti - Asti Ovest station.
Asti to Isernia train services, operated by Trenord, depart from Asti station.
The best way to get from Asti to Isernia is to train via Rome which takes 8h 4m and costs €65 - €190. Alternatively, you can bus, which costs €60 - €90 and takes 11h 58m.
What companies run services between Asti, Italy and Isernia, Italy?
You can take a train from Asti to Isernia via Milan Rogoredo and Roma Termini in around 8h 4m. Alternatively, you can take a bus from Asti - Asti Ovest to Isernia via Caianello and Casello - A1 Ingresso Caianello in around 11h 58m.
- Website
- ita-airways.com
Flights from Turin Caselle Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- €50–120
Flights from Milan Linate Airport to Naples Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €40–130
Flights from Milan Linate Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 3m
- When
- Monday to Saturday
- Estimated price
- €40–130
Flights from Genoa Cristoforo Colombo Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €60–120
Flights from Genoa Cristoforo Colombo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €40–100
- Website
- ryanair.com
Flights from Turin Caselle Airport to Naples Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €40–120
Flights from Genoa Cristoforo Colombo Airport to Naples Airport
- Ave. Duration
- 1h 20m
- When
- Friday and Sunday
- Estimated price
- €40–110
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €40–130
Flights from Turin Caselle Airport to Abruzzo Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €30–200
Flights from Milano Malpensa Airport to Abruzzo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €23–140
- Website
- easyjet.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €23–130
- Website
- aeroitalia.com
Flights from Genoa Cristoforo Colombo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–220
- Website
- flexflight.dk
Flights from Genoa Cristoforo Colombo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–220
- Website
- volotea.com
Flights from Turin Caselle Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €26–150
Flights from Genoa Cristoforo Colombo Airport to Naples Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €27–95
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Asti to Milan Rogoredo
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a day
- Estimated price
- €9–12
- Website
- https://www.trenord.it/en/
Train from Asti to Milano Lambrate
- Ave. Duration
- 1h 33m
- Frequency
- 5 times a day
- Estimated price
- €9–12
- Website
- https://www.trenord.it/en/
Train from Asti to Milano Centrale
- Ave. Duration
- 1h 41m
- Frequency
- 5 times a day
- Estimated price
- €9–12
- Website
- https://www.trenord.it/en/
Train from Milano Centrale to Malpensa Aeroporto T1
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milan Rogoredo to Roma Termini
- Ave. Duration
- 2h 53m
- Frequency
- Hourly
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €13–55
- Website
- https://www.trenitalia.com/en.html
Train from Asti to Torino Aeroporto Di Caselle
- Ave. Duration
- 1h 33m
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- €9–14
- Website
- https://www.trenitalia.com/en.html
Train from Cassino to Isernia
- Ave. Duration
- 42 min
- Frequency
- 4 times a day
- Estimated price
- €5–6
- Website
- https://www.trenitalia.com/en.html
Train from Asti to Genova P.Za Principe
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–12
- Website
- https://www.trenitalia.com/en.html
Train from Asti to Milano Lambrate
- Ave. Duration
- 1h 33m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Asti to Cassino
- Ave. Duration
- 8h 55m
- Frequency
- Twice a week
- Estimated price
- €40–60
- Website
- https://www.trenitalia.com/en.html
- 2nd Class
- €40–60
Train from Asti to Genova P.Za Principe
- Ave. Duration
- 1h 21m
- Frequency
- 3 times a day
- Estimated price
- €12–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Asti to Genova P.Za Principe
- Ave. Duration
- 1h 1m
- Frequency
- Once daily
- Estimated price
- €14–26
- Schedules at
- trenitalia.com
- Phone
- +39 0827 34 117
- info@gruppodimaio.it
- Website
- gruppodimaio.it
Bus from Asti - Asti Ovest to Caianello
- Ave. Duration
- 9h 50m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- gruppodimaio.it
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Casello - A1 Ingresso Caianello to Isernia
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €7–22
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Isernia
- Ave. Duration
- 9h 54m
- Frequency
- Once daily
- Estimated price
- €45–70
- Website
- https://www.flixbus.co.uk
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €14–27
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 50m
- Frequency
- 3 times a week
- Estimated price
- €7–20
- Website
- https://www.itabus.it/en/home
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Want to know more about travelling around Italy
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More Questions & Answers
Asti to Isernia bus services, operated by Gruppo Di Maio, arrive at Caianello station.
Asti to Isernia train services, operated by Trenord, arrive at Milan Rogoredo station.
Yes, the driving distance between Asti to Isernia is 769 km. It takes approximately 7h 23m to drive from Asti to Isernia.
Book your Asti to Isernia train tickets online with Omio.
There are 435+ hotels available in Isernia.




































