There are 8 ways to get from Assisi to Palermo by bus, plane, car, car ferry, train (Trenitalia), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Perugia Sant'Egidio Airport, fly
best- Take the bus from P.za Matteotti Assisi to Aeroporto Internazionale dell'Umbriabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane PEG - PMO
3h 50m€61–239Train to Fiumicino International Airport, fly
cheapest- Take the train from Assisi to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane FCO - PMO
7h 30m€43–168Bus
- Take the bus from Assisi - Piazza San Pietro to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus Autoservizi Salemi S201
15h 55m€58–81Drive, car ferry
- Drive from Assisi to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
16h 1m€87–124Train (Trenitalia)
- Take the train from Assisi to Roma Terminitrain 4735 / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
16h 27m€109–207Train, train to Pisa International Airport, fly
- Take the train from Assisi to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
8h 24m€72–282Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Assisi to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane BLQ - PMO
7h 53m€46–282Train, bus
- Take the train from Assisi to Roma Tiburtinatrain 4735 / ...
- Take the bus from Roma, Autostazione Tiburtina to Palermobus N592
18h 47m€99–167
Assisi to Palermo by bus
Comparing Your Travel Options
The cheapest way to get from Assisi to Palermo is to bus which costs €55 - €85 and takes 15h 55m.
The fastest way to get from Assisi to Palermo is to bus and fly which takes 3h 50m and costs €60 - €240.
No, there is no direct bus from Assisi to Palermo. However, there are services departing from Assisi - Piazza San Pietro and arriving at Palermo Terminal Bus via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 15h 55m.
No, there is no direct train from Assisi to Palermo. However, there are services departing from Assisi and arriving at Palermo Centrale via Roma Termini. The journey, including transfers, takes approximately 16h 27m.
The distance between Assisi and Palermo is 600 km.
The best way to get from Assisi to Palermo without a car is to bus which takes 15h 55m and costs €55 - €85.
It takes approximately 3h 50m to get from Assisi to Palermo, including transfers.
Assisi to Palermo bus services, operated by Sulga Autolinee, depart from Assisi - Piazza San Pietro station.
Assisi to Palermo train services, operated by Trenitalia, depart from Assisi station.
The best way to get from Assisi to Palermo is to bus which takes 15h 55m and costs €55 - €85. Alternatively, you can train, which costs €100 - €210 and takes 16h 27m.
What companies run services between Assisi, Italy and Palermo, Italy?
You can take a bus from Assisi - Piazza San Pietro to Palermo Terminal Bus via Roma, Autostazione Tiburtina in around 15h 55m. Alternatively, you can take a bus from P.za Matteotti Assisi to Palermo Centrale via Assisi, Assisi, and Roma Termini in around 16h 27m.
- Website
- ryanair.com
Flights from Perugia Sant'Egidio Airport to Palermo Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Wednesday, and Thursday
- Estimated price
- €50–230
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €23–120
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €40–160
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Alghero
- Ave. Duration
- 3h 35m
- When
- Tuesday
- Estimated price
- €40–160
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Bari
- Ave. Duration
- 3h 55m
- When
- Sunday
- Estimated price
- €40–160
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Assisi to Roma Termini
- Ave. Duration
- 2h 43m
- Frequency
- Every 3 hours
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Assisi to Roma Termini
- Ave. Duration
- 2h 43m
- Frequency
- Every 3 hours
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Assisi to Firenze S.M.N.
- Ave. Duration
- 2h 29m
- Frequency
- Every 2 hours
- Estimated price
- €20–29
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Assisi to Firenze S.M.N.
- Ave. Duration
- 2h 29m
- Frequency
- Every 2 hours
- Estimated price
- €20–29
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Assisi to Roma Tiburtina
- Ave. Duration
- 2h 32m
- Frequency
- Every 3 hours
- Estimated price
- €19–27
- Website
- Trenitalia
- Phone
- +39 06 44101
- fsbusitalia@pec.it
- Website
- fsbusitalia.it
Bus from P.za Matteotti Assisi to Aeroporto Internazionale dell'Umbria
- Ave. Duration
- 30 min
- Frequency
- 5 times a day
- Estimated price
- €3–4
- Schedules at
- Busitalia Umbria
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
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Booking & Getting There
Assisi to Palermo bus services, operated by Sulga Autolinee, arrive at Roma, Autostazione Tiburtina station.
Assisi to Palermo train services, operated by Trenitalia, arrive at Roma Termini station.
Book your Assisi to Palermo bus tickets online with Omio.
There are 6241+ hotels available in Palermo.













