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How to get fromAssisi to Iserniaby bus, train (Trenitalia) or car

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There are 4 ways to get from Assisi to Isernia by bus, train (Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Rome

    best
    1. Take the bus from Assisi - Piazza San Pietro to Roma, Autostazione Tiburtinabus
    2. Take the bus from Roma, Autostazione Tiburtina to IserniabusRome Tiburtina
    6h 20m
    €31–53
  2. Train

    cheapest
    1. Take the train from Foligno to Roma Terminitrain4153 / ...
    2. Take the train from Roma Termini to IserniatrainRe
    6h 45m
    €25–86
  3. Drive 286.4 km

    1. Drive from Assisi to Iserniacar286.4 km
    4h 10m
    €45–65
  4. Bus

    1. Take the bus from Santa Maria degli Angeli to Pescarabus1509
    2. Take the bus from Chieti to Iserniabus433
    8h 45m
    €32–73

Assisi to Isernia by bus

Calendar6Weekly Buses
Duration6h 20mAverage Duration
Ticket€31Cheapest Price
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Questions & Answers

What companies run services between Assisi, Italy and Isernia, Italy?

You can take a bus from Assisi - Piazza San Pietro to Isernia via Roma, Autostazione Tiburtina in around 6h 20m. Alternatively, you can take a bus from P.za Matteotti Assisi to Isernia via Foligno - Stazione, Foligno, and Roma Termini in around 6h 45m.

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