There are 4 ways to get from Assisi to Isernia by bus, train (Trenitalia), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Rome
best- Take the bus from Assisi - Piazza San Pietro to Roma, Autostazione Tiburtina
- Take the bus from Roma, Autostazione Tiburtina to IserniaRome Tiburtina
6h 20m€31–53Train
cheapest- Take the train from Foligno to Roma Termini4153 / ...
- Take the train from Roma Termini to IserniaRe
6h 45m€25–86Drive 286.4 km
- Drive from Assisi to Isernia286.4 km
4h 10m€45–65Bus
- Take the bus from Santa Maria degli Angeli to Pescara1509
- Take the bus from Chieti to Isernia433
8h 45m€32–72
Assisi to Isernia by bus
Questions & Answers
The cheapest way to get from Assisi to Isernia is to train which costs €25 - €90 and takes 6h 45m.
The fastest way to get from Assisi to Isernia is to drive which takes 4h 10m and costs €40 - €65.
No, there is no direct bus from Assisi to Isernia. However, there are services departing from Assisi - Piazza San Pietro and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 6h 20m.
The distance between Assisi and Isernia is 371 km. The road distance is 286.4 km.
The best way to get from Assisi to Isernia without a car is to bus via Rome which takes 6h 20m and costs €30 - €55.
It takes approximately 6h 20m to get from Assisi to Isernia, including transfers.
Assisi to Isernia bus services, operated by Sulga Autolinee, depart from Assisi - Piazza San Pietro station.
The best way to get from Assisi to Isernia is to bus via Rome which takes 6h 20m and costs €30 - €55. Alternatively, you can train, which costs €25 - €90 and takes 6h 45m.
Assisi to Isernia bus services, operated by Sulga Autolinee, arrive at Roma, Autostazione Tiburtina station.
Yes, the driving distance between Assisi to Isernia is 286 km. It takes approximately 4h 10m to drive from Assisi to Isernia.
What companies run services between Assisi, Italy and Isernia, Italy?
You can take a bus from Assisi - Piazza San Pietro to Isernia via Roma, Autostazione Tiburtina in around 6h 20m. Alternatively, you can take a bus from P.za Matteotti Assisi to Isernia via Foligno - Stazione, Foligno, and Roma Termini in around 6h 45m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Foligno to Roma Termini
- Ave. Duration
- 1h 55m
- Frequency
- Every 2 hours
- Estimated price
- €14–25
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Foligno to Roma Termini
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €45–65
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Foligno to Roma Termini
- Ave. Duration
- 2h 4m
- Frequency
- 3 times a day
- Estimated price
- €11–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 075 5009641
- info@sulga.it
- Website
- sulga.it
Bus from Assisi - Piazza San Pietro to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 10m
- Frequency
- 6 times a week
- Estimated price
- €23–26
- Schedules at
- sulga.it
- 2nd Class
- €23–26
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €16–27
- Website
- https://www.flixbus.co.uk
Bus from Santa Maria degli Angeli to Pescara
- Ave. Duration
- 3h 34m
- Frequency
- Once daily
- Estimated price
- €19–28
- Website
- https://www.flixbus.co.uk
Bus from Chieti to Isernia
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- €10–27
- Website
- https://www.flixbus.co.uk
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