There are 8 ways to get from Assen to Karlsruhe by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Frankfurt Airport (FRA)
best- Take the train from Assen to Zwolle
- Take the train from Zwolle to Arnhem Centraal
- Take the train from Arnhem Centraal to Frankfurt(M) Flughafen FernbfIce
- Take the train from Frankfurt to Karlsruhe Hauptbahnhof43 / ...
7h 24m€85–308Bus
cheapest- Take the bus from Groningen central station to Karlsruhe central train station027
13h 1m€40–52Train, night train
- Take the train from Assen to Zwolle
- Take the night train from Deventer to Koeln HbfNj
- Take the night train from Koeln Hbf to Karlsruhe HbfNj
11h 11m€92–568Drive 570 km
- Drive from Assen to Karlsruhe570 km
4h 58m€102–147Train
- Take the train from Assen to ZwolleSprinter / ...
- Take the train from Deventer to Karlsruhe HbfNightjet
9h 48m€107–358Train to Amsterdam Airport Schiphol, fly to Stuttgart Airport, train
- Take the train from Assen to Schiphol Airport
- Fly from Amsterdam Airport Schiphol (AMS) to Stuttgart Airport (STR)AMS - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbf
6h 47m€161–396Bus, train to Bremen Airport, fly to Stuttgart Airport, train
- Take the bus from Groningen, Hoofdstation to Leer
- Take the train from Leer(Ostfriesl) to Bremen Hbf
- Fly from Bremen Airport (BRE) to Stuttgart Airport (STR)BRE - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbf
8h 8m€154–401Train to Amsterdam Airport Schiphol, fly to Frankfurt, train
- Take the train from Assen to Schiphol Airport
- Fly from Amsterdam Airport Schiphol (AMS) to Frankfurt (FRA)AMS - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhof
7h 3m€158–418
Assen to Karlsruhe by train
Questions & Answers
The cheapest way to get from Assen to Karlsruhe is to bus which costs €40 - €55 and takes 13h 1m.
The fastest way to get from Assen to Karlsruhe is to drive which takes 4h 58m and costs €100 - €150.
No, there is no direct bus from Assen to Karlsruhe station. However, there are services departing from Assen, Maasstraat and arriving at Karlsruhe central train station via Groningen central station. The journey, including transfers, takes approximately 13h 1m.
No, there is no direct train from Assen to Karlsruhe. However, there are services departing from Assen and arriving at Karlsruhe Hauptbahnhof via Zwolle, Arnhem Centraal and Frankfurt. The journey, including transfers, takes approximately 7h 24m.
The distance between Assen and Karlsruhe is 611 km. The road distance is 570 km.
The best way to get from Assen to Karlsruhe without a car is to train via Frankfurt Airport (FRA) which takes 7h 24m and costs €80 - €310.
It takes approximately 7h 24m to get from Assen to Karlsruhe, including transfers.
Assen to Karlsruhe bus services, operated by FlixBus, depart from Groningen central station.
Assen to Karlsruhe train services, operated by Nederlandse Spoorwegen (NS), depart from Assen station.
The best way to get from Assen to Karlsruhe is to train via Frankfurt Airport (FRA) which takes 7h 24m and costs €80 - €310. Alternatively, you can bus, which costs €40 - €55 and takes 13h 1m.
What companies run services between Assen, Netherlands and Karlsruhe, Germany?
You can take a train from Assen to Karlsruhe Hauptbahnhof via Zwolle, Arnhem Centraal, and Frankfurt in around 7h 24m. Alternatively, FlixBus operates a bus from Groningen central station to Karlsruhe central train station 4 times a week. Tickets cost €35–45 and the journey takes 11h 30m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Stuttgart Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €55–360
Flights from Bremen Airport to Stuttgart Airport via Amsterdam Airport Schiphol
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €75–430
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €40–280
- Website
- lufthansa.com
Flights from Amsterdam Airport Schiphol to Stuttgart Airport via Frankfurt
- Ave. Duration
- 2h 58m
- When
- Every day
- Estimated price
- €110–490
Flights from Bremen Airport to Stuttgart Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €150–500
Flights from Bremen Airport to Stuttgart Airport via Frankfurt
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €150–500
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €100–300
- Website
- swiss.com
Flights from Amsterdam Airport Schiphol to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Monday, Tuesday, and Thursday
- Estimated price
- €100–380
- Website
- eurowings.com
Flights from Bremen Airport to Stuttgart Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €75–230
- Website
- airdolomiti.it
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €110–260
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Assen to Zwolle
- Ave. Duration
- 44 min
- Frequency
- Every 20 minutes
- Estimated price
- €13–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €13–20
- 1st Class
- €24–40
Train from Zwolle to Arnhem Centraal
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- €18
- Website
- https://www.ns.nl/en
Train from Arnhem Centraal to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €50–180
- Website
- https://www.ns.nl/en
- 2nd Class
- €50–75
- 1st Class
- €100–180
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €21–70
- Website
- https://www.ns.nl/en
- 2nd Class
- €21–35
- 1st Class
- €40–70
Train from Deventer to Karlsruhe Hbf
- Ave. Duration
- 7h 21m
- Frequency
- Once a week
- Estimated price
- €85–310
- Website
- https://www.ns.nl/en
- 2nd Class
- €85–130
- 1st Class
- €180–310
Train from Assen to Schiphol Airport
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €30–100
- Website
- https://www.ns.nl/en
- 2nd Class
- €30–45
- 1st Class
- €60–100
- Phone
- 0800-0232 545
- Website
- arriva.nl
Train from Assen to Zwolle
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–19
- Website
- https://www.arriva.nl/en/
- 2nd Class
- €17–19
Train from Assen to Schiphol Airport
- Ave. Duration
- 1h 57m
- Frequency
- Once a week
- Estimated price
- €40–44
- Website
- https://www.arriva.nl/en/
- 2nd Class
- €40–44
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Arnhem Centraal to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 39m
- Frequency
- Every 2 hours
- Estimated price
- €35–120
- Website
- https://int.bahn.de/en
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 2 hours
- Estimated price
- €18–50
- Website
- https://int.bahn.de/en
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €18–27
- Website
- https://int.bahn.de/en
Train from Leer(Ostfriesl) to Bremen Hbf
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €20–28
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Deventer to Koeln Hbf
- Ave. Duration
- 3h 25m
- Frequency
- Twice a week
- Estimated price
- €35–260
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €258–260
- Couchette Carriage
- €130–150
- Seating Carriage
- €35–45
Night train from Koeln Hbf to Karlsruhe Hbf
- Ave. Duration
- 4h 19m
- Frequency
- Once a week
- Estimated price
- €35–260
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €258–260
- Couchette Carriage
- €130–150
- Seating Carriage
- €35–45
- Phone
- +49 711 400 534 44
- service@gabw-bahn.de
- Website
- go-ahead-bw.de
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- go-ahead-bw.de
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 7821 9960770
- info@sweg.de
- Website
- sweg.de
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Schedules at
- sweg.de
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Leer(Ostfriesl) to Bremen Hbf
- Ave. Duration
- 1h 24m
- Frequency
- Every 2 hours
- Estimated price
- €17–24
- Website
- https://int.bahn.de/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Groningen central station to Karlsruhe central train station
- Ave. Duration
- 11h 30m
- Frequency
- 4 times a week
- Estimated price
- €35–45
- Website
- https://www.flixbus.co.uk
Bus from Groningen, Hoofdstation to Leer
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- €10–21
- Website
- https://www.flixbus.co.uk
- Phone
- 0800-0232 545
- Website
- arriva.nl
Bus from Groningen, Hoofdstation to Leer
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- https://www.arriva.nl/en/
- Phone
- +31 30 751 5155
- Website
- ns.nl
Bus from Groningen, Hoofdstation to Leer
- Ave. Duration
- 1h 15m
- Frequency
- Every 4 hours
- Website
- https://www.ns.nl/en
Want to know more about travelling around Germany
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More Questions & Answers
Assen to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Assen to Karlsruhe train services, operated by Nederlandse Spoorwegen (NS), arrive at Zwolle station.
Yes, the driving distance between Assen to Karlsruhe is 570 km. It takes approximately 4h 58m to drive from Assen to Karlsruhe.
There are 814+ hotels available in Karlsruhe.




























