There are 7 ways to get from Arequipa to Santiago by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Arequipa  •  6 h 55 min

  1. Fly from Arequipa (AQP) to Santiago (SCL) AQP - SCL

$164 - $849

Cheapest option

Bus Turbus  •  37 h 51 min

  1. Take the bus from Arequipa to Tacna
  2. Take the bus from Tacna to Arica
  3. Take the bus from Arica to Santiago - Terminal Alameda

$63 - $174

5 alternative options

Bus, bus to Arica, fly  •  12 h 14 min

  1. Take the bus from Arequipa to Moquegua
  2. Take the bus from Moquegua to Tacna
  3. Take the bus from Tacna to Arica
  4. Fly from Arica (ARI) to Santiago (SCL) ARI - SCL

$162 - $543

Bus Rutas De America  •  29 h 36 min

  1. Take the bus from Arequipa to Tacna
  2. Take the bus from Chacalluta to Santiago Via Santiago de Chile / ...

$203 - $281

Bus Fichtur VIP  •  36 h 35 min

  1. Take the bus from Arequipa to Tacna
  2. Take the bus from Tacna to Arica
  3. Take the bus from Arica to Santiago

$66 - $127

Bus Expreso Internacional Ormeño  •  2 days 16 h

  1. Take the bus from Arequipa to Tacna
  2. Take the bus from Tacna to Santiago

$91 - $147

Drive  •  30 h 34 min

  1. Drive from Arequipa to Santiago 1562.4 miles

$250 - $380

What companies run services between Arequipa, Peru and Santiago, Chile?

LATAM Chile, Viva Airlines Peru S.A.C and four other airlines fly from Arequipa to Santiago hourly. Alternatively, you can take a bus from Arequipa to Santiago via Tacna and Chacalluta in around 29 h 36 min.

Airlines
LATAM Chile
Website
latam.com
Flights from Arequipa to Santiago via Lima
Ave. Duration
6 h 41 min
When
Every day
Estimated price
$210 - $850
Flights from Arequipa to Santiago via Lima, Antofagasta
Ave. Duration
10 h 24 min
When
Sunday
Estimated price
$220 - $850
Flights from Arica to Santiago
Ave. Duration
2 h 33 min
When
Every day
Estimated price
$230 - $1,100
Sky Airline
Website
skyairline.com
Flights from Arica to Santiago
Ave. Duration
2 h 35 min
When
Every day
Estimated price
$130 - $460
Bus operators
Tepsa
Website
tepsa.com.pe
Bus from Moquegua to Tacna
Ave. Duration
2 h 32 min
Frequency
Once daily
Estimated price
$14 - $45
Schedules at
tepsa.com.pe
Suite
$35 - $45
Regular
$14 - $20
Adsubliata
Phone
+56 58 58 226 2495
Bus from Tacna to Arica
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$4
Buses Norte Grande
Phone
+56993068508
Website
busesnortegrande.cl
Bus from Tacna to Arica
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$4
Schedules at
busesnortegrande.cl
Oltursa
Website
oltursa.pe
Bus from Arequipa to Tacna
Ave. Duration
5 h 15 min
Frequency
Once daily
Estimated price
$10 - $26
Schedules at
oltursa.pe
Terminal Internacional ASEVERTRANS Ltda
Phone
(58) 241 390
Website
terminaldebuses.com
Bus from Tacna to Arica
Ave. Duration
2 h
Frequency
Every 30 minutes
Estimated price
$7
Schedules at
terminaldebuses.com
Fichtur VIP
Phone
+56 (02) 7205232
Website
fichtur.cl
Bus from Arica to Santiago
Ave. Duration
27 h 20 min
Frequency
5 times a day
Estimated price
$54
Schedules at
viajaenbus.cl
Expreso Norte
Turbus
Website
turbus.cl
Bus from Arica to Santiago - Terminal Alameda
Ave. Duration
28 h 10 min
Frequency
Twice daily
Estimated price
$45 - $140
Schedules at
turbus.cl
2nd Class
$45 - $95
Premium
$95 - $140
1st Class
$120 - $180

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Want to know more about Flixbus?, French strikes 2018: What are my alternative transport options? and How to get from London to Edinburgh - to help you get the most out of your next trip.

Questions & Answers

The distance between Arequipa and Santiago is 1899 km. The road distance is 2500 km.

The cheapest way to get from Arequipa to Santiago is to bus which costs $65 - $130 and takes 36 h 35 min.

The quickest way to get from Arequipa to Santiago is to fly which takes 6 h 55 min and costs $160 - $850.

No, there is no direct bus from Arequipa to Santiago. However, there are services departing from Arequipa and arriving at Santiago via Tacna and Arica. The journey, including transfers, takes approximately 36 h 35 min.

It takes approximately 6 h 55 min to get from Arequipa to Santiago, including transfers.