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There are 4 ways to get from Arequipa to Santiago by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  6 h 20 min

  1. Fly from Arequipa (AQP) to Santiago (SCL) AQP - SCL

$163 - $849

Cheapest option

Bus Expreso Norte  •  36 h 19 min

  1. Take the bus from Arequipa to Tacna
  2. Take the bus from Tacna to Arica
  3. Take the bus from Arica to Santiago - San Borja

$56 - $142

2 alternative options

Bus Skybus  •  30 h

  1. Take the bus from Arequipa to Santiago Via Cucuta

Drive  •  30 h 34 min

  1. Drive from Arequipa to Santiago 1562.4 miles

$250 - $380

Questions & Answers

The cheapest way to get from Arequipa to Santiago is to bus which costs $55 - $150 and takes 36 h 19 min.

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The quickest way to get from Arequipa to Santiago is to fly which costs $160 - $850 and takes 6 h 20 min.

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Yes, there is a direct bus departing from Arequipa and arriving at Santiago. Services depart once daily, and operate every day. The journey takes approximately 30 h.

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The distance between Arequipa and Santiago is 1899 km. The road distance is 2499.8 km.

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The best way to get from Arequipa to Santiago without a car is to bus which takes 30 h and costs .

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It takes approximately 6 h 20 min to get from Arequipa to Santiago, including transfers.

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Arequipa to Santiago bus services, operated by Skybus, depart from Arequipa station.

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The best way to get from Arequipa to Santiago is to fly which takes 6 h 20 min and costs $160 - $850. Alternatively, you can bus, which costs and takes 30 h.

Mode details

There is no direct flight from Arequipa Airport to Santiago Airport. The quickest flight takes 5 h 46 min and has one stopover.

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Arequipa to Santiago bus services, operated by Skybus, arrive at Santiago station.

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Map of how to get from Arequipa to Santiago.
Launch map view
  • Distance: 1186.8 miles
  • Duration: 6 h 20 min

What companies run services between Arequipa, Peru and Santiago, Chile?

LATAM Chile, Avianca - Aerovías del Continente Americano S.A. and Peruvian Airlines fly from Arequipa to Santiago hourly. Alternatively, Skybus operates a bus from Arequipa to Santiago once daily, and the journey takes 30 h.

Airlines
LATAM Chile
Website
latam.com
Flights from Arequipa to Santiago via Lima
Ave. Duration
6 h 18 min
When
Every day
Estimated price
$210 - $850
Flights from Arequipa to Santiago via Lima, Antofagasta
Ave. Duration
8 h 57 min
When
Sunday
Estimated price
$220 - $850
Bus operators
Skybus
Phone
+58 414 8448807
Website
facebook.com
Bus from Arequipa to Santiago
Ave. Duration
30 h
Frequency
Once daily
Schedules at
facebook.com
Bus from Arequipa to Tacna
Ave. Duration
4 h
Frequency
Once daily
Schedules at
facebook.com
Oltursa
Phone
+511 708 5000
Website
oltursa.pe
Bus from Arequipa to Tacna
Ave. Duration
5 h 15 min
Frequency
Once daily
Estimated price
$10 - $50
Schedules at
oltursa.pe
Book at
oltursa.pe
Double VIP
$30 - $50
Bed
$14 - $19
VIP
$21 - $30
Chasquitur
Phone
+56 58 231967
Website
terminaldebuses.com
Bus from Tacna to Arica
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$3
Schedules at
bus-america.com
Adsubliata
Phone
+56 58 262 495
Website
terminaldebuses.com
Bus from Tacna to Arica
Ave. Duration
3 h 1 min
Frequency
Hourly
Estimated price
$6
Schedules at
terminaldebuses.com
Buses Norte Grande
Phone
+56 58 222 8603
Email
busesnortegrande_zarzuri@hotmail.com
Website
busesng.cl
Bus from Tacna to Arica
Ave. Duration
3 h 1 min
Frequency
Hourly
Estimated price
$3
Schedules at
busesng.cl
Book at
busesng.cl
Expreso Norte
Fichtur VIP
Phone
+56 (02) 7205232
Website
fichtur.cl
Bus from Arica to Santiago
Ave. Duration
27 h 20 min
Frequency
3 times a day
Estimated price
$50
Schedules at
viajaenbus.cl
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Arica to Santiago
Ave. Duration
26 h 20 min
Frequency
Twice daily
Estimated price
$65 - $90
Schedules at
pullman.cl

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Stansted Airport into central London, Which side of Niagara Falls should I choose (and how do I get there)? and Getting to Rome from the airport - to help you get the most out of your next trip.

More Questions & Answers

Santiago is 1 h ahead of Arequipa. It is currently 8:53 PM in Arequipa and 10:53 PM in Santiago.

Yes, the driving distance between Arequipa to Santiago is 2500 km. It takes approximately 30 h 34 min to drive from Arequipa to Santiago.

Get driving directions

LATAM Chile offers flights from Arequipa Airport to Santiago Airport.

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There are 2159+ hotels available in Santiago. Prices start at $44 USD per night.

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The best way to get from Arequipa to Arequipa Airport is to taxi which takes 12 min and costs $3 - $4.

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