There are 4 ways to get from Arequipa to La Serena by plane, bus or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended option
Fly • 8h 58m
$308 - $1,209
Cheapest option
Bus • 27h 17m
$40 - $122
2 alternative options
Bus via Iquique • 30h 2m
$47 - $121
Drive • 26h 10m
$210 - $310
Questions & Answers
The cheapest way to get from Arequipa to La Serena is to bus which costs $35 - $130 and takes 27h 17m.
The quickest way to get from Arequipa to La Serena is to fly which costs $300 - $1,300 and takes 8h 58m.
No, there is no direct bus from Arequipa to La Serena. However, there are services departing from Arequipa and arriving at La Serena via Tacna and Arica. The journey, including transfers, takes approximately 27h 17m.
The distance between Arequipa and La Serena is 1502 km. The road distance is 2028.9 km.
The best way to get from Arequipa to La Serena without a car is to bus which takes 27h 17m and costs $35 - $130.
It takes approximately 8h 58m to get from Arequipa to La Serena, including transfers.
Arequipa to La Serena bus services, operated by Flores Hermanos, depart from Arequipa station.
The best way to get from Arequipa to La Serena is to fly which takes 8h 58m and costs $300 - $1,300. Alternatively, you can bus, which costs $35 - $130 and takes 27h 17m.
There is no direct flight from Arequipa Airport to La Serena Airport. The quickest flight takes 8h 10m and has two stopovers.
Arequipa to La Serena bus services, operated by Pullman Bus, arrive at La Serena station.

- Distance: 938.8 miles
- Duration: 8h 58m
What companies run services between Arequipa, Peru and La Serena, Chile?
LATAM Chile and Peruvian Airlines fly from Arequipa to La Serena every 3 hours. Alternatively, you can take a bus from Arequipa to La Serena via Tacna and Arica in around 27h 17m.

- Website
- latam.com
Flights from Arequipa to La Serena via Lima, Santiago
- Ave. Duration
- 8h 50m
- When
- Wednesday, Thursday, Friday and Sunday
- Estimated price
- $330 - $1,300
Flights from Arequipa to La Serena via Lima, Calama
- Ave. Duration
- 10h 51m
- When
- Monday
- Estimated price
- $310 - $1,200
Flights from Arequipa to La Serena via Lima, Antofagasta
- Ave. Duration
- 15h 23m
- When
- Sunday
- Estimated price
- $300 - $1,200
Flights from Arequipa to La Serena via Lima, Antofagasta, Santiago
- Ave. Duration
- 12h 35m
- When
- Sunday
- Estimated price
- $340 - $1,300
Flights from Arequipa to La Serena via Lima, Mendoza, Santiago
- Ave. Duration
- 13h 49m
- When
- Thursday
- Estimated price
- $340 - $1,300

- Phone
- +51 1 4800725
- floresruta@floreshnos.com
- Website
- floreshnos.pe
Bus from Arequipa to Tacna
- Ave. Duration
- 5h 30m
- Frequency
- Hourly
- Estimated price
- $7 - $24
- Schedules at
- floreshnos.pe
- Book at
- floreshnos.pe

- Phone
- +511 708 5000
- Website
- oltursa.pe
Bus from Arequipa to Tacna
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $14 - $50
- Schedules at
- oltursa.pe
- Book at
- oltursa.pe
- Double VIP
- $30 - $50
- Bed
- $14 - $19
- VIP
- $22 - $30

- Phone
- +56 58 231967
- Website
- terminaldebuses.com
Bus from Tacna to Arica
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $3
- Schedules at
- terminaldebuses.com
- Phone
- +56 58 262 495
- Website
- terminaldebuses.com
Bus from Tacna to Arica
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $6
- Schedules at
- terminaldebuses.com

- Phone
- +56 58 222 8603
- busesnortegrande_zarzuri@hotmail.com
- Website
- busesng.cl
Bus from Tacna to Arica
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $3
- Schedules at
- busesng.cl
- Book at
- busesng.cl

- Phone
- +56 600 600 0018
- Website
- pullmanbus.com
Bus from Arica to La Serena
- Ave. Duration
- 19h 50m
- Frequency
- 4 times a day
- Estimated price
- $50 - $70
- Schedules at
- pullmanbus.com
Bus from Iquique to La Serena
- Ave. Duration
- 17h 30m
- Frequency
- 5 times a day
- Estimated price
- $40 - $55
- Schedules at
- pullmanbus.com

- Phone
- +56 22 822 7500
- atencion_clientes@turbus.cl
- Website
- turbus.cl
Bus from Arica to La Serena
- Ave. Duration
- 20h 45m
- Frequency
- 5 times a day
- Estimated price
- $30 - $70
- Book at
- pasajebus.com
- 2nd Class
- $30 - $70
- Premium
- $70 - $100
- 1st Class
- $90 - $130
Bus from Iquique Rodovario to La Serena
- Ave. Duration
- 17h 10m
- Frequency
- 4 times a day
- Estimated price
- $28 - $55
- Book at
- pasajebus.com
- 2nd Class
- $28 - $55
- Premium
- $55 - $85
- 1st Class
- $70 - $110

- Website
- expresonorte.cl
Bus from Arica to La Serena
- Ave. Duration
- 21h 32m
- Frequency
- 5 times a day
- Estimated price
- $50 - $70
- Schedules at
- expresonorte.cl

- Phone
- +56 (57) 248 3147
Bus from Arica to La Serena
- Ave. Duration
- 24h 26m
- Frequency
- Once daily
- Estimated price
- $50 - $65
- Schedules at
- voyhoy.com

- Phone
- +56 55 229 8299
- contacto@srtcielo.com
- Website
- pasajescielo.cl
Bus from Arica to Iquique
- Ave. Duration
- 4h 15m
- Frequency
- Hourly
- Estimated price
- $9 - $14
- Schedules at
- pasajescielo.cl

- Phone
- 951690977
- servicioalcliente@ciktur.cl
- Website
- ciktur.cl
Bus from Iquique to La Serena
- Ave. Duration
- 18h 14m
- Frequency
- 3 times a day
- Estimated price
- $54
- Schedules at
- ciktur.cl
- Book at
- altanetpasajes.cl
- Website
- busesevans.com
Bus from Iquique to La Serena
- Ave. Duration
- 14h 36m
- Frequency
- Once daily
- Schedules at
- busesevans.com
Want to know more about travelling around the world?
Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including The London Underground: Essential tips to navigate the Tube, Bali: What to do if Mount Agung erupts and Italy Travel Guides - to help you get the most out of your next trip.
More Questions & Answers
La Serena is 2h ahead of Arequipa. It is currently 10:07 AM in Arequipa and 12:07 PM in La Serena.
Yes, the driving distance between Arequipa to La Serena is 2029 km. It takes approximately 26h 10m to drive from Arequipa to La Serena.
LATAM Chile offers flights from Arequipa Airport to La Serena Airport.
There are 2379+ hotels available in La Serena. Prices start at $68 USD per night.
The best way to get from Arequipa to Arequipa Airport is to taxi which takes 13m and costs $3 - $4.