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How to get fromAppleton to Missouriby plane, bus, train, bus (Flixbus, Greyhound) or car

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There are 9 ways to get from Appleton to Missouri by plane, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Columbia Regional Airport

    best
    1. Fly from Appleton International Airport (ATW) to Columbia Regional Airport (COU)plane plane ATW - COU
    4h 17m
    $123–427

  2. Bus

    cheapest
    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    16h 25m
    $105–192

  3. Bus, train

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    13h 14m
    $135–302

  4. Drive 570.6 mi

    1. Drive from Appleton to Kansas Citycar car 570.6 mi
    10h 16m
    $105–151

  5. Fly Appleton International Airport to Lambert–St. Louis International Airport

    1. Fly from Appleton International Airport (ATW) to Lambert–St. Louis International Airport (STL)plane plane ATW - STL
    4h 39m
    $111–625

  6. Fly Appleton International Airport to Kansas City

    1. Fly from Appleton International Airport (ATW) to Kansas City (MCI)plane plane ATW - MCI
    5h 56m
    $108–572

  7. Fly Green Bay to Lambert–St. Louis International Airport

    1. Fly from Green Bay (GRB) to Lambert–St. Louis International Airport (STL)plane plane GRB - STL
    6h 15m
    $129–645

  8. Bus to General Mitchell International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Appleton Amtrak Station to Milwaukee Airport Amtrak Bus Stopbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    5h 55m
    $147–956

  9. Bus, train via Milwaukee

    1. Take the bus from Appleton Amtrak Station to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    13h 27m
    $146–365

Appleton to Missouri by bus, foot, train, and tram

Calendar5Weekly Services
Duration13h 14mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

What companies run services between Appleton, WI, USA and Missouri, USA?

American Airlines and United Airlines fly from Appleton International Airport (ATW) to Columbia Regional Airport (COU) every 4 hours. Alternatively, you can take a bus from Appleton Transit Center to Kansas City Bus Station via Chicago Bus Station and St Louis Bus Station in around 16h 25m.

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