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How to get fromAppleton to Knoxvilleby plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Flixbus)

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Appleton to Knoxville

Rome2Rio compared 7 ways to get from Appleton to Knoxville. The best route is Fly from Appleton International Airport, a distance of 998.654 km.

  1. Fly from Appleton International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Mcghee Tyson Airport (TYS)plane plane ATW - TYS
    4h 26m
    $193–792

  2. Drive 715.3 mi

    cheapest
    1. Drive from Appleton to Knoxvillecar car 715.3 mi
    12h 34m
    $131–189

  3. Bus, train

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    39h 49m
    $535–982

  4. Bus via Detroit

    1. Take the bus from Appleton Transit Center to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    41h 47m
    $350–563

  5. Fly from Green Bay

    1. Fly from Green Bay (GRB) to Mcghee Tyson Airport (TYS)plane plane GRB - TYS
    5h 55m
    $271–1,112

  6. Bus, train via Ossining

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    40h 26m
    $480–859

  7. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    43h 7m
    $256–390

Appleton International Airport (ATW) to Mcghee Tyson Airport (TYS) flights

Calendar73Weekly Planes
Duration5h 42mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from Appleton to Knoxville.ExpandLaunch map view
  • Distance: 648.5 mi
  • Duration: 4h 26m

What companies run services between Appleton, WI, USA and Knoxville, TN, USA?

United Airlines, Delta, and American Airlines fly from Appleton International Airport (ATW) to Mcghee Tyson Airport (TYS) every 3 hours. Alternatively, you can take a bus from Appleton Transit Center to Knoxville via Detroit Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 41h 47m.

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