There are 6 ways to get from Appleton to Iowa by plane, bus (Flixbus, Greyhound), car, bus, train, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Des Moines
best- Fly from Appleton International Airport (ATW) to Des Moines (DSM)plane ATW - DSM
4h 11m$135–693Fly to Quad City International Airport
cheapest- Fly from Appleton International Airport (ATW) to Quad City International Airport (MLI)plane ATW - MLI
5h 20m$65–324Bus
- Take the bus from Appleton Transit Center to Chicago Bus Stationbus FlixBus 2550
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
12h 5m$84–164Drive 378.6 mi
- Drive from Appleton to Des Moinescar 378.6 mi
7h 5m$70–100Bus, train
- Take the bus from Appleton to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
12h 48m$95–199Bus, shuttle
- Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus
- Take the bus from La Crosse to Rochester, MNbus
- Take a shuttle bus from Rochester Sinclair to Owatonna, MN
- Take the bus from Owatonna to Des Moinesbus
13h 40m$126–200
Appleton International Airport (ATW) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Appleton to Iowa is to drive which costs $65 - $100 and takes 7h 5m.
The fastest way to get from Appleton to Iowa is to fly which takes 4h 11m and costs $130 - $700.
The distance between Appleton and Iowa is 334 miles. The road distance is 380.8 miles.
The best way to get from Appleton to Iowa without a car is to bus which takes 12h 5m and costs $80 - $170.
It takes approximately 4h 11m to get from Appleton to Iowa, including transfers.
The best way to get from Appleton to Iowa is to fly which takes 4h 11m and costs $130 - $700. Alternatively, you can bus, which costs $80 - $170 and takes 12h 5m.
Yes, the driving distance between Appleton to Iowa is 381 miles. It takes approximately 7h 5m to drive from Appleton to Iowa.
There are 127+ hotels available in Iowa.
What companies run services between Appleton, WI, USA and Iowa, USA?
Delta, United Airlines, and American Airlines fly from Appleton International Airport (ATW) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Appleton Transit Center to Des Moines via Chicago Bus Station and Des Moines in around 12h 5m.
- Website
- united.com
Flights from Appleton International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $100–650
Flights from Appleton International Airport to Des Moines via Denver
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Appleton International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $45–300
- Website
- aa.com
Flights from Appleton International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $100–650
Flights from Appleton International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $45–300
Flights from Appleton International Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $120–600
- Website
- delta.com
Flights from Appleton International Airport to Des Moines via Minneapolis
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $100–650
Flights from Appleton International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Appleton International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Appleton Transit Center to Chicago Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $25–45
- Schedules at
- flixbus.com
Bus from Appleton to Milwaukee
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $13–24
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Appleton to Milwaukee
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $23–27
- Schedules at
- golamers.com
Bus from Appleton Valley Transit to La Crosse Grand River Station
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $34–39
- Schedules at
- golamers.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Rochester, MN
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Owatonna to Des Moines
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $50–70
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–70
- Phone
- +1 (888) 736-9190
- customerservice@landtoair.net
- Website
- landtoairexpress.com
Shuttle from Rochester Sinclair to Owatonna, MN
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $5–40
- Schedules at
- landtoairexpress.com
- Adult
- $5–40
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