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How to get fromApex to Chicagoby bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

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There are 6 ways to get from Apex to Chicago by bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 311 bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from W Willams St at Upchurch St to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    4h 51m
    $158–230

  2. Line 311 bus to Raleigh-Durham International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from W Willams St at Upchurch St to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    5h 24m
    $62–340

  3. Bus

    1. Take the bus from Durham to Washington Union Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Washington Union Station to Chicago Bus Stationbus bus Greyhound US0164
    25h 48m
    $150–256

  4. Train (Amtrak)

    1. Take the train from Cary to Chicago Union Stationtrain train Floridian
    26h 32m
    $552–952

  5. Drive  777 mi

    1. Drive from Apex to Chicagocar car 777 mi
    13h 49m
    $142–205

  6. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Cary to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    6h 54m
    $134–482

Apex to Chicago by bus

Calendar14Weekly Buses
Duration25h 48mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Apex to Chicago.ExpandLaunch map view
  • Distance: 661.3 mi
  • Duration: 4h 51m

What companies run services between Apex, NC, USA and Chicago, IL, USA?

You can take a bus from E Williams St at S Mason St to Chicago Bus Station via Regional Transit Center, Durham Station, Durham, and Washington Union Station in around 25h 48m. Alternatively, Amtrak operates a train from Cary to Chicago Union Station once daily. Tickets cost $550–950 and the journey takes 25h 12m.

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