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How to get fromAntwerp to Sienaby plane, train, train (Eurostar), bus, car or car train

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There are 11 ways to get from Antwerp to Siena by plane, train, train (Eurostar), bus, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Brussels Airport to Florence Peretola Airport, train

    best
    1. Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)planeBRU - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain
    7h 5m
    €72–247

  2. Bus

    cheapest
    1. Take the bus from Antwerp - Rooseveltplaats to Milano, Autostazione LampugnanobusBlaBlaCar Bus
    2. Take the bus from Milano, Autostazione Lampugnano to SienabusN528 / ...
    20h 15m
    €59–170

  3. Train

    1. Take the train from Anvers-Central to Chambery Challes Les Eauxtrain
    2. Take the train from Chambery Challes Les Eaux to Milano CentraletrainFr
    3. Take the train from Milano Centrale to Florence Santa Maria Novellatrain
    4. Take the train from Firenze S.M.N. to SienatrainRe
    14h 38m
    €268–493

  4. Drive 1,273 km

    1. Drive from Antwerp to Sienacar1,273 km
    12h 55m
    €197–284

  5. Fly Brussels Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Brussels Airport (BRU) to Bologna Guglielmo Marconi Airport (BLQ)planeBRU - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 34m
    €83–314

  6. Train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport, train

    1. Take the train from Antwerpen-Centraal to Schiphol Airporttrain
    2. Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)planeAMS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 45m
    €111–356

  7. Train, bus to Brussels South Charleroi Airport, fly to Pisa International Airport

    1. Take the train from Anvers-Central to Brussel-Zuid / Bruxelles-Miditrain
    2. Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
    3. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)planeCRL - PSA
    4. Take the train from Pisa Centrale to Empolitrain
    5. Take the train from Empoli to Sienatrain
    8h 1m
    €95–245

  8. Train, bus to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Anvers-Central to Brussel-Zuid / Bruxelles-Miditrain
    2. Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
    3. Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)planeCRL - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train
    5. Take the train from Firenze S.M.N. to Sienatrain
    9h 1m
    €111–344

  9. Train, train to Eindhoven Airport, fly to Pisa International Airport

    1. Take the train from Anvers-Central to Bredatrain
    2. Take the train from Breda to Eindhoventrain
    3. Fly from Eindhoven Airport (EIN) to Pisa International Airport (PSA)planeEIN - PSA
    4. Take the train from Pisa Centrale to Empolitrain
    5. Take the train from Empoli to Sienatrain
    8h 21m
    €93–273

  10. Train, bus

    1. Take the train from Anvers-Central to Brussels-NordtrainIc / ...
    2. Take the bus from Brussels-North Station to Bolognabus
    3. Take the train from Bologna Centrale to Firenze S.M.N.trainFr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131
    21h 37m

  11. Drive, car train

    1. Drive from Antwerp to Düsseldorf Hbfcar
    2. Take the car train from Düsseldorf Hbf to Villach Hbfcartrain
    3. Drive from Villach Hbf to Sienacar
    13h 44m
    €213–1,170

Antwerp to Siena by train

Calendar2Weekly Trains
Duration14h 38mAverage Duration
Ticket€268Cheapest Price
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Questions & Answers

What companies run services between Antwerp, Belgium and Siena, Italy?

You can take a train from Anvers-Central to Siena via Chambery Challes Les Eaux, Milano Centrale, and Firenze S.M.N. in around 14h 38m. Alternatively, you can take a bus from Antwerp - Rooseveltplaats to Siena via Milano, Autostazione Lampugnano in around 20h 15m.

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