From Antwerpen Centraal train to Bruxelles-Central. 41 min 7€. From Anvers bus to Bruxelles Centre - Gare Midi. 55 min 7€. From Antwerp taxi to Brussels. 34 min 121€. From Antwerp drive to Brussels. 34 min 6€. From Antwerp rideshare to Brussels. 54 min 3€.
Belgian Railways (NMBS/SNCB) operates a train from Antwerp to Brussels every 30 minutes. Tickets cost $7 - $11 and the journey takes 41 min. Alternatively, Ouibus operates a bus from Antwerp to Brussels twice daily. Tickets cost $2 - $4 and the journey takes 55 min. CityBusExpress also services this route twice a week.