There are 4 ways to get from Antofagasta to La Serena by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 20 min

  1. Fly from Antofagasta (ANF) to La Serena (LSC) ANF - LSC

$55 - $330

Cheapest option

Bus Turbus  •  11 h 25 min

  1. Take the bus from Antofagasta to La Serena Iquique / ...

$20 - $65

2 alternative options

Bus Pluss Chile  •  15 h 49 min

  1. Take the bus from Antofagasta to Baquedano
  2. Take the bus from Baquedano to La Serena

$45 - $48

Drive  •  10 h 32 min

  1. Drive from Antofagasta to La Serena 562.3 miles

$90 - $140

Questions & Answers

The cheapest way to get from Antofagasta to La Serena is to bus which costs $20 - $65 and takes 11 h 25 min.

More details

The quickest way to get from Antofagasta to La Serena is to fly which costs $55 - $330 and takes 3 h 20 min.

More details

The distance between Antofagasta and La Serena is 700 km. The road distance is 899.7 km.

Get driving directions

It takes approximately 3 h 20 min to get from Antofagasta to La Serena, including transfers.

More details

Yes, there is a direct bus departing from Antofagasta and arriving at La Serena. Services depart every three hours, and operate every day. The journey takes approximately 11 h 25 min.

More details

What companies run services between Antofagasta, Chile and La Serena, Chile?

Sky Airline and LATAM Chile fly from Antofagasta to La Serena once daily. Alternatively, Turbus operates a bus from Antofagasta to La Serena every 3 hours. Tickets cost $20 - $65 and the journey takes 11 h 25 min. Three other operators also service this route.

Airlines
Sky Airline
Website
skyairline.com
Flights from Antofagasta to La Serena
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$75 - $330
LATAM Chile
Website
latam.com
Flights from Antofagasta to La Serena
Ave. Duration
1 h 27 min
When
Monday and Sunday
Estimated price
$130 - $1,100
Bus operators
Turbus
Website
turbus.cl
Bus from Antofagasta to La Serena
Ave. Duration
11 h 25 min
Frequency
Every 3 hours
Estimated price
$20 - $65
Schedules at
turbus.cl
2nd Class
$20 - $40
Premium
$40 - $65
1st Class
$50 - $75
Expreso Norte
Buses Evans
Website
busesevans.com
Bus from Antofagasta to La Serena
Ave. Duration
9 h 32 min
Frequency
Once daily
Schedules at
busesevans.com
Pullman Carmelita
Phone
+56 (57) 248 3147
Bus from Antofagasta to La Serena
Ave. Duration
13 h 29 min
Frequency
Once daily
Estimated price
$30 - $45
Schedules at
voyhoy.com
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Antofagasta to Baquedano
Ave. Duration
1 h 6 min
Frequency
Every 2 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Bus from Baquedano to La Serena
Ave. Duration
12 h 46 min
Frequency
Every 3 hours
Estimated price
$42
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Antofagasta to Baquedano
Ave. Duration
1 h 4 min
Frequency
Every 4 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Bus from Baquedano to La Serena
Ave. Duration
12 h 58 min
Frequency
Every 4 hours
Estimated price
$43
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Antofagasta to Baquedano
Ave. Duration
1 h 5 min
Frequency
Every 4 hours
Estimated price
$3 - $5
Schedules at
pullman.cl

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Need to know: Jadrolinija, Need to know: Greyhound and Heading to Europe? Read this before you buy a Eurail Pass - to help you get the most out of your next trip.