There are 4 ways to get from Antofagasta to La Serena by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 15 min

  1. Fly from Antofagasta (ANF) to La Serena (LSC) ANF - LSC

$62 - $331

Cheapest option

Bus Turbus  •  11 h 25 min

  1. Take the bus from Antofagasta to La Serena Iquique / ...

$19 - $60

2 alternative options

Bus Pullman Bus  •  12 h 44 min

  1. Take the bus from Antofagasta to Chañaral Valparaíso / ...
  2. Take the bus from Chañaral to La Serena Santiago / ...

$31 - $66

Drive  •  10 h 32 min

  1. Drive from Antofagasta to La Serena 562.3 miles

$90 - $140

Questions & Answers

Yes, there is a direct bus departing from Antofagasta and arriving at La Serena. Services depart every two hours, and operate every day. The journey takes approximately 11 h 25 min.

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The distance between Antofagasta and La Serena is 700 km. The road distance is 899.7 km.

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The best way to get from Antofagasta to La Serena without a car is to bus which takes 11 h 25 min and costs .

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It takes approximately 3 h 15 min to get from Antofagasta to La Serena, including transfers.

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Antofagasta to La Serena bus services, operated by Turbus, depart from Antofagasta station.

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The best way to get from Antofagasta to La Serena is to fly which takes 3 h 15 min and costs . Alternatively, you can bus, which costs and takes 11 h 25 min.

Mode details

The quickest flight from Antofagasta Airport to La Serena Airport is the direct flight which takes 1 h 20 min.

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Antofagasta to La Serena bus services, operated by Turbus, arrive at La Serena station.

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Yes, the driving distance between Antofagasta to La Serena is 900 km. It takes approximately 10 h 32 min to drive from Antofagasta to La Serena.

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LATAM Chile, JetSMART and Sky Airline offer flights from Antofagasta Airport to La Serena Airport.

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Map of how to get from Antofagasta to La Serena.
Launch map view
  • Distance: 437.7 miles
  • Duration: 3 h 15 min

What companies run services between Antofagasta, Chile and La Serena, Chile?

Sky Airline, LATAM Chile and JetSMART fly from Antofagasta to La Serena twice daily. Alternatively, Turbus operates a bus from Antofagasta to La Serena every 2 hours. Tickets cost $19 - $60 and the journey takes 11 h 25 min. Four other operators also service this route.

Airlines
Sky Airline
Website
skyairline.com
Flights from Antofagasta to La Serena
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$75 - $330
LATAM Chile
Website
latam.com
Flights from Antofagasta to La Serena
Ave. Duration
1 h 22 min
When
Monday and Sunday
Estimated price
$130 - $1,100
JetSMART
Website
jetsmart.com
Flights from Antofagasta to La Serena
Ave. Duration
1 h 22 min
When
Wednesday, Thursday and Friday
Estimated price
$55 - $400
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Antofagasta to La Serena
Ave. Duration
11 h 25 min
Frequency
Every 2 hours
Estimated price
$19 - $60
Schedules at
turbus.cl
2nd Class
$19 - $40
Premium
$40 - $60
1st Class
$50 - $75
Expreso Norte
Website
expresonorte.cl
Bus from Antofagasta to La Serena
Ave. Duration
12 h 4 min
Frequency
Hourly
Estimated price
$30 - $45
Schedules at
expresonorte.cl
Book at
expresonorte.cl
Bus from Antofagasta to Chañaral
Ave. Duration
5 h 6 min
Frequency
Every 4 hours
Estimated price
$19 - $26
Schedules at
expresonorte.cl
Book at
expresonorte.cl
Bus from Chañaral to La Serena
Ave. Duration
6 h 58 min
Frequency
Every 4 hours
Estimated price
$21 - $30
Schedules at
expresonorte.cl
Book at
expresonorte.cl
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Antofagasta to La Serena
Ave. Duration
11 h 40 min
Frequency
Every 3 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Antofagasta to La Serena
Ave. Duration
11 h 54 min
Frequency
Every 3 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Bus from Antofagasta to Chañaral
Ave. Duration
5 h 2 min
Frequency
Every 4 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Bus from Chañaral to La Serena
Ave. Duration
6 h 52 min
Frequency
Every 4 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Pullman Carmelita
Phone
+56 (57) 248 3147
Bus from Antofagasta to La Serena
Ave. Duration
13 h 29 min
Frequency
Once daily
Estimated price
$30 - $45
Schedules at
voyhoy.com
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Antofagasta to Chañaral
Ave. Duration
3 h 30 min
Frequency
4 times a day
Estimated price
$14 - $18
Schedules at
pullman.cl
Bus from Chañaral to La Serena
Ave. Duration
7 h 35 min
Frequency
Hourly
Estimated price
$17 - $40
Schedules at
pullman.cl
Los Corsarios
Phone
+56 02-7205231
Website
loscorsarios.cl
Bus from Chañaral to La Serena
Ave. Duration
7 h 20 min
Frequency
Once daily
Estimated price
$22
Schedules at
viajaenbus.cl

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More Questions & Answers

There are 1643+ hotels available in La Serena. Prices start at $53 USD per night.

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The best way to get from Antofagasta to Antofagasta Airport is to bus which takes 20 min and costs .

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