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There are 3 ways to get from Antofagasta to La Serena by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3h 15m

  1. Fly from Antofagasta (ANF) to La Serena (LSC) ANF - LSC

$62 - $331

Cheapest option

Bus  •  11h 25m

  1. Take the bus from Antofagasta to La Serena Iquique / ...

$19 - $45

1 alternative option

Drive  •  10h 32m

  1. Drive from Antofagasta to La Serena 562.3 miles

$90 - $140

Questions & Answers

The cheapest way to get from Antofagasta to La Serena is to bus which costs $19 - $45 and takes 11h 25m.

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The quickest way to get from Antofagasta to La Serena is to fly which costs $60 - $340 and takes 3h 15m.

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Yes, there is a direct bus departing from Antofagasta and arriving at La Serena. Services depart hourly, and operate every day. The journey takes approximately 11h 25m.

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The distance between Antofagasta and La Serena is 700 km. The road distance is 899.7 km.

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The best way to get from Antofagasta to La Serena without a car is to bus which takes 11h 25m and costs $19 - $45.

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It takes approximately 3h 15m to get from Antofagasta to La Serena, including transfers.

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Antofagasta to La Serena bus services, operated by Turbus, depart from Antofagasta station.

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The best way to get from Antofagasta to La Serena is to fly which takes 3h 15m and costs $60 - $340. Alternatively, you can bus, which costs $19 - $45 and takes 11h 25m.

Mode details

The quickest flight from Antofagasta Airport to La Serena Airport is the direct flight which takes 1h 20m.

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Antofagasta to La Serena bus services, operated by Turbus, arrive at La Serena station.

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Map of how to get from Antofagasta to La Serena.
Launch map view
  • Distance: 437.7 miles
  • Duration: 3h 15m

What companies run services between Antofagasta, Chile and La Serena, Chile?

Sky Airline, JetSMART and LATAM Chile fly from Antofagasta to La Serena twice daily. Alternatively, Turbus operates a bus from Antofagasta to La Serena every 2 hours. Tickets cost $19 - $40 and the journey takes 11h 25m. Six other operators also service this route.

Airlines
Sky Airline
Website
skyairline.com
Flights from Antofagasta to La Serena
Ave. Duration
1h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $330
JetSMART
Website
jetsmart.com
Flights from Antofagasta to La Serena
Ave. Duration
1h 22m
When
Wednesday, Thursday and Friday
Estimated price
$55 - $400
LATAM Chile
Website
latam.com
Flights from Antofagasta to La Serena
Ave. Duration
1h 24m
When
Monday and Sunday
Estimated price
$130 - $1,100
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Antofagasta to La Serena
Ave. Duration
11h 25m
Frequency
Every 2 hours
Estimated price
$19 - $40
Book at
pasajebus.com
2nd Class
$19 - $40
Premium
$40 - $60
1st Class
$50 - $75
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Antofagasta to La Serena
Ave. Duration
11h 15m
Frequency
Every 3 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Antofagasta to La Serena
Ave. Duration
11h 55m
Frequency
Twice daily
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Pullman Bus
Phone
+56 600 600 0018
Website
pullmanbus.com
Bus from Antofagasta to La Serena
Ave. Duration
10h 50m
Frequency
Twice daily
Estimated price
$29 - $40
Schedules at
pullmanbus.com
Buses Evans
Website
busesevans.com
Bus from Antofagasta to La Serena
Ave. Duration
9h 32m
Frequency
Once daily
Schedules at
busesevans.com
Pullman Carmelita
Phone
+56 (57) 248 3147
Bus from Antofagasta to La Serena
Ave. Duration
13h 29m
Frequency
Once daily
Estimated price
$30 - $45
Schedules at
voyhoy.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Flying into Beijing?, Train travel in Spain: A guide to Renfe and Need to know: Greyhound - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Antofagasta to La Serena is 900 km. It takes approximately 10h 32m to drive from Antofagasta to La Serena.

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JetSMART, LATAM Chile and Sky Airline offer flights from Antofagasta Airport to La Serena Airport.

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There are 2302+ hotels available in La Serena. Prices start at $65 USD per night.

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The best way to get from Antofagasta to Antofagasta Airport is to bus which takes 20m and costs .

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