There are 6 ways to get from Antofagasta to Cusco by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  7 h 30 min

  1. Fly from Antofagasta (ANF) to Cuzco (CUZ) ANF - CUZ

$331 - $997

Cheapest option

Bus, Tour  •  30 h 54 min

  1. Take the bus from Antofagasta to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the Tour from Arequipa to Cusco

$98 - $223

4 alternative options

Bus  •  32 h

  1. Take the bus from Antofagasta to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the bus from Arequipa to Cusco

$113 - $263

Bus via Chivay  •  33 h 33 min

  1. Take the bus from Antofagasta to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the bus from Arequipa to Chivay
  5. Take the bus from Chivay to Cusco

$99 - $174

Bus, train  •  2 days 12 h

  1. Take the bus from Antofagasta to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the train from Arequipa to Cusco - Wanchaq

$238 - $6,103

Drive  •  21 h 50 min

  1. Drive from Antofagasta to Cusco 962 miles

$150 - $230

Questions & Answers

No, there is no direct bus from Antofagasta to Cusco. However, there are services departing from Antofagasta and arriving at Cusco via Arica, Tacna and Arequipa. The journey, including transfers, takes approximately 30 h 54 min.

More details

The distance between Antofagasta and Cusco is 1138 km. The road distance is 1539.1 km.

Get driving directions

The best way to get from Antofagasta to Cusco without a car is to bus and Tour which takes 30 h 54 min and costs .

More details

It takes approximately 7 h 30 min to get from Antofagasta to Cusco, including transfers.

More details

Antofagasta to Cusco bus services, operated by Turbus, depart from Antofagasta station.

More details

The best way to get from Antofagasta to Cusco is to fly which takes 7 h 30 min and costs . Alternatively, you can bus and Tour, which costs and takes 30 h 54 min.

Mode details

There is no direct flight from Antofagasta Airport to Cuzco Airport. The quickest flight takes 5 h 5 min and has one stopover.

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Antofagasta to Cusco bus services, operated by Peru Hop, arrive at Cusco station.

More details

Cusco is 1 h behind Antofagasta. It is currently 3:03 AM in Antofagasta and 1:03 AM in Cusco.

Yes, the driving distance between Antofagasta to Cusco is 1539 km. It takes approximately 21 h 50 min to drive from Antofagasta to Cusco.

Get driving directions

Map of how to get from Antofagasta to Cusco.
Launch map view
  • Distance: 711.5 miles
  • Duration: 7 h 30 min

What companies run services between Antofagasta, Chile and Cusco, Peru?

LATAM Chile flies from Antofagasta to Cusco every 4 hours. Alternatively, you can take a bus from Antofagasta to Cusco via Arica, Tacna, and Arequipa in around 30 h 54 min.

Airlines
LATAM Chile
Website
latam.com
Flights from Antofagasta to Cuzco via Lima
Ave. Duration
5 h 5 min
When
Monday, Thursday and Saturday
Estimated price
$400 - $1,100
Flights from Antofagasta to Cuzco via Santiago
Ave. Duration
7 h 42 min
When
Tuesday, Wednesday and Friday
Estimated price
$400 - $1,100
Flights from Antofagasta to Cuzco via Santiago, Lima
Ave. Duration
9 h 37 min
When
Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$400 - $1,100
Train operators
PeruRail
Phone
51-84-581414
Email
reservas@perurail.com
Website
perurail.com
Train from Arequipa to Cusco - Wanchaq
Ave. Duration
40 h 58 min
Frequency
Once a week
Estimated price
$210 - $6,000
Schedules at
perurail.com
Book at
pax1.perurail.com
VIP
$210 - $6,000
Regular
$600 - $850
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Antofagasta to Arica
Ave. Duration
10 h 24 min
Frequency
Every 3 hours
Estimated price
$16 - $50
Schedules at
turbus.cl
2nd Class
$16 - $35
Premium
$35 - $50
1st Class
$40 - $60
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Antofagasta to Arica
Ave. Duration
10 h 20 min
Frequency
5 times a day
Estimated price
$24 - $35
Schedules at
pullman.cl
bus
Bus from Arica to Tacna
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$3
Flores Hermanos
Phone
+51 1 4800725
Email
floresruta@floreshnos.com
Website
floreshnos.pe
Bus from Tacna to Arequipa
Ave. Duration
6 h
Frequency
Hourly
Estimated price
$9 - $24
Schedules at
floreshnos.pe
Bus from Arequipa to Cusco
Ave. Duration
11 h
Frequency
Twice daily
Estimated price
$13 - $24
Schedules at
floreshnos.pe
Skybus
Phone
+58 414 8448807
Website
facebook.com
Bus from Tacna to Arequipa
Ave. Duration
4 h
Frequency
Twice daily
Schedules at
facebook.com
Oltursa
Website
oltursa.pe
Bus from Tacna to Arequipa
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$10 - $50
Schedules at
oltursa.pe
Book at
oltursa.pe
Double VIP
$30 - $50
Bed
$14 - $19
VIP
$21 - $30
Bus from Arequipa to Cusco
Ave. Duration
10 h 15 min
Frequency
Twice daily
Estimated price
$14 - $50
Schedules at
oltursa.pe
Double VIP
$35 - $50
Bed
$16 - $22
VIP
$24 - $35
Peru Hop
Phone
+51 1 2422140
Email
info@peruhop.com
Bus from Arequipa to Cusco
Ave. Duration
11 h 45 min
Frequency
Once daily
Estimated price
$70 - $120
Schedules at
peruhop.com
Book at
peruhop.com
Transportes Reyna
Phone
+51 54 429339
Email
transreyna@reyna.com.pe
Website
reyna.com.pe
Bus from Arequipa to Cusco
Ave. Duration
8 h 30 min
Frequency
Twice daily
Estimated price
$18
Schedules at
reyna.com.pe
Bus from Arequipa to Chivay
Ave. Duration
4 h 26 min
Frequency
Every 2 hours
Estimated price
$6
Schedules at
reyna.com.pe
Movil Tours
Phone
716-8000
Email
info@moviltours.com.pe
Website
moviltours.com.pe
Bus from Arequipa to Cusco
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$17 - $45
Schedules at
moviltours.com.pe
Economy
$17 - $25
Regular
$22 - $35
Suite
$30 - $45
Transzela
4M
Phone
+51 54 452296
Email
informes@4m-expresss.com
Website
busperu4m.com
Bus from Chivay to Cusco
Ave. Duration
9 h 45 min
Frequency
3 times a week
Estimated price
$65
Schedules at
busperu4m.com

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More Questions & Answers

LATAM Chile offers flights from Antofagasta Airport to Cuzco Airport.

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There are 1342+ hotels available in Cusco. Prices start at $18 USD per night.

More details

The best way to get from Antofagasta to Antofagasta Airport is to bus which takes 20 min and costs .

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