There are 8 ways to get from Anna Maria to Key West by taxi, bus, ferry, shuttle, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, bus, ferry
best- Take the taxi from Anna Maria to Sarasota Cattlemen Transfer Center
- Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Take the ferry from Fort Myers Beach, FL to Key West, FL
7h 30m$262–303Line 5 bus, line 304 bus, line 203 bus to Saint Petersburg–Clearwater International Airport, fly
cheapest- Take the bus from Pine Ave/Tarpon St to Gulf Dr/42Nd St
- Take the bus from Gulf Dr/42Nd St to Downtown Station
- Take the bus from Downtown Station to Psta Grand Central Station
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)PIE - EYW
6h 31m$64–390Bus, shuttle
- Take the bus from St Petersburg 7-11 to Miami AirportTampa
- Take a shuttle bus from Miami, FL - International Airport to Key West, FLTo the Keys
14h 29m$179–302Drive 373.3 mi
- Drive from Anna Maria to Key West373.3 mi
7h 32m$69–99Fly from Sarasota–Bradenton International Airport
- Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)SRQ - EYW
8h 19m$423–620Bus, ferry
- Take the bus from Bradenton to Fort MyersHouston
- Take the ferry from Fort Myers Beach, FL to Key West, FLFort Myers Beach
10h 17m$205–242Bus
- Take the bus from Bradenton to Miami
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
15h 24m$99–150Line 5 bus, line 304 bus, line 203 bus to Tampa, fly
- Take the bus from Pine Ave/Tarpon St to Gulf Dr/42Nd St
- Take the bus from Gulf Dr/42Nd St to Downtown Station
- Take the bus from Downtown Station to 34Th St S/54Th Ave S
- Fly from Tampa (TPA) to Key West International Airport (EYW)TPA - EYW
6h 27m$117–466
Anna Maria to Key West by bus and shuttle
Questions & Answers
The cheapest way to get from Anna Maria to Key West is to drive which costs $65 - $100 and takes 7h 32m.
The fastest way to get from Anna Maria to Key West is to line 5 bus and line 304 bus and line 203 bus and fly which takes 6h 27m and costs $110 - $470.
The distance between Anna Maria and Key West is 252 miles. The road distance is 375.5 miles.
The best way to get from Anna Maria to Key West without a car is to taxi and bus and ferry which takes 7h 30m and costs $260 - $310.
It takes approximately 7h 30m to get from Anna Maria to Key West, including transfers.
The best way to get from Anna Maria to Key West is to fly which takes 8h 19m and costs $420 - $650. Alternatively, you can bus, which costs $95 - $150 and takes 15h 24m.
Yes, the driving distance between Anna Maria to Key West is 375 miles. It takes approximately 7h 32m to drive from Anna Maria to Key West.
There are 799+ hotels available in Key West.
What companies run services between Anna Maria, FL, USA and Key West, FL, USA?
Delta, American Airlines, and Allegiant Air fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Pine Ave/Tarpon St to N Roosevelt & 3rd Street via Gulf Dr/42Nd St, Downtown Station, Manatee Ave E/25Th St E, Bradenton, Miami, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 15h 24m.
- Website
- allegiantair.com
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Covington
- Ave. Duration
- 6h 53m
- When
- Monday
- Estimated price
- $220–1,000
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 1m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $50–360
- Website
- aa.com
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $170–850
- Website
- delta.com
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $150–800
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $110–440
- Website
- spirit.com
Flights from Tampa to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 2h 49m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $85–380
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $19–35
- Schedules at
- flixbus.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from St Petersburg 7-11 to Miami Airport
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $27–85
- Website
- https://www.redcoachusa.com
- Web
- $27–85
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Bradenton to Fort Myers
- Ave. Duration
- 2h 12m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- omnibusexpress.com
Bus from Bradenton to Miami
- Ave. Duration
- 5h 48m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- omnibusexpress.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 (941) 749-7116
- mcat@mymanatee.org
- Website
- mymanatee.org
Bus from Pine Ave/Tarpon St to Gulf Dr/42Nd St
- Ave. Duration
- 12 min
- Frequency
- Every 30 minutes
- Estimated price
- $1–2
- Schedules at
- mymanatee.org
- Seniors 80+, Children under 5
- $0
- Free trolleys
- $0
- students, Disabled, Seniors 60-79
- $1–2
- Adults 18-59
- $1–2
Bus from Gulf Dr/42Nd St to Downtown Station
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $1–4
- Schedules at
- mymanatee.org
- Seniors 80+, Children under 5
- $0
- Free trolleys
- $0
- students, Disabled, Seniors 60-79
- $1–4
- Adults 18-59
- $1–4
Bus from Downtown Station to Psta Grand Central Station
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $1–8
- Schedules at
- mymanatee.org
- Seniors 80+, Children under 5
- $0
- Free trolleys
- $0
- students, Disabled, Seniors 60-79
- $1–8
- Adults 18-59
- $1–8
Bus from Downtown Station to 34Th St S/54Th Ave S
- Ave. Duration
- 34 min
- Frequency
- Once daily
- Estimated price
- $1–7
- Schedules at
- mymanatee.org
- Seniors 80+, Children under 5
- $0
- Free trolleys
- $0
- students, Disabled, Seniors 60-79
- $1–7
- Adults 18-59
- $1–7
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
- Ave. Duration
- 45 min
- Estimated price
- $80–100
Yellow Cab of Sarasota
- Phone
- +1 941-955-3341
- Website
- yellowcabofsarasota.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide














