There are 4 ways to get from Ann Arbor to Key West by bus, plane, bus (Greyhound), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly
best- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Fly from Detroit (DTW) to Key West International Airport (EYW)DTW - EYW
6h 43m$108–460Bus
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit - Grand Circus Park
- Take the bus from Detroit Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
40h 33m$182–424Bus, train
- Take the bus from Ann Arbor Amtrak Station to Toledo
- Take the train from Toledo to Miami Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
2d 4hDrive 1,484.5 mi
- Drive from Ann Arbor to Key West1,484.5 mi
25h 45m$271–392
Ann Arbor to Key West by bus and foot
Questions & Answers
The cheapest way to get from Ann Arbor to Key West is to bus which costs $180 - $430 and takes 40h 33m.
The fastest way to get from Ann Arbor to Key West is to bus and fly which takes 6h 43m and costs $100 - $460.
No, there is no direct bus from Ann Arbor to Key West. However, there are services departing from Ann Arbor- Blake Transit Ctr., MI and arriving at N Roosevelt & 3rd Street via Rosa Parks Transit Center - Bay 10, Detroit Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 40h 33m.
The distance between Ann Arbor and Key West is 1262 miles. The road distance is 1493.2 miles.
The best way to get from Ann Arbor to Key West without a car is to bus which takes 40h 33m and costs $180 - $430.
It takes approximately 6h 43m to get from Ann Arbor to Key West, including transfers.
Ann Arbor to Key West bus services, operated by D2A2, depart from Ann Arbor- Blake Transit Ctr., MI station.
Ann Arbor to Key West bus services, operated by D2A2, arrive at Detroit - Grand Circus Park station.
Yes, the driving distance between Ann Arbor to Key West is 1493 miles. It takes approximately 25h 45m to drive from Ann Arbor to Key West.
There are 869+ hotels available in Key West.
What companies run services between Ann Arbor, MI, USA and Key West, FL, USA?
You can take a bus from Ann Arbor- Blake Transit Ctr., MI to N Roosevelt & 3rd Street via Detroit - Grand Circus Park, Rosa Parks Transit Center - Bay 10, Lafayette & Fifth, Detroit Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 40h 33m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- delta.com
Flights from Detroit to Key West International Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $100–500
- Website
- spirit.com
Flights from Detroit to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 5h 20m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $90–440
- Website
- flybreeze.com
Flights from Detroit to Key West International Airport via Tampa
- Ave. Duration
- 4h 50m
- When
- Tuesday
- Estimated price
- $90–430
- Website
- allegiantair.com
Flights from Detroit to Key West International Airport via Indianapolis
- Ave. Duration
- 5h 10m
- When
- Thursday and Sunday
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Toledo to Miami Amtrak Station
- Ave. Duration
- 42h 20m
- Frequency
- Once daily
- Estimated price
- $230–420
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 517-333-0400
- info@michiganflyer.com
- Website
- michiganflyer.com
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
- Phone
- +1 517-333-0400
- info@michiganflyer.com
- Website
- d2a2.com
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit - Grand Circus Park
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $8
- Website
- https://d2a2.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Detroit Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $70–200
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 600-1455
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Ann Arbor Amtrak Station to Toledo
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide







