There are 4 ways to get from Ann Arbor to Isabela by bus, plane, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Aguadilla
best- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Aguadilla (BQN)plane DTW - BQN
9h 51m$138–620Bus, fly to Eugenio María De Hostos Airport, drive
cheapest- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Eugenio María De Hostos Airport (MAZ)plane DTW - MAZ
- Drive from Eugenio María De Hostos Airport (MAZ) to Isabelacar
11h$91–394Bus, fly to Luis Munoz Marin International Airport, drive
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Luis Munoz Marin International Airport (SJU)plane DTW - SJU
- Drive from Hyatt Hacienda del Mar to Isabelacar
9h 33m$196–431Bus, fly to Ponce, drive
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Ponce (PSE)plane DTW - PSE
- Drive from Ponce (PSE) to Isabelacar
15h 43m$157–683
Detroit (DTW) to Aguadilla (BQN) flights
Questions & Answers
The cheapest way to get from Ann Arbor to Isabela is to bus and fly and drive which costs $90 - $400 and takes 11h.
The fastest way to get from Ann Arbor to Isabela is to bus and fly and drive which takes 9h 33m and costs $190 - $440.
The distance between Ann Arbor and Isabela is 3111 km.
It takes approximately 9h 51m to get from Ann Arbor to Isabela, including transfers.
There are 233+ hotels available in Isabela.
What companies run services between Ann Arbor, MI, USA and Isabela, Puerto Rico?
There is no direct connection from Ann Arbor to Isabela. However, you can take the bus to Detroit Metro Airport, walk to North Terminal, take the bus to McNamara Terminal, walk to Detroit (DTW) airport, fly to Aguadilla (BQN), then drive to Isabela. Alternatively, you can take the bus to Detroit Metro Airport, walk to North Terminal, take the bus to McNamara Terminal, walk to Detroit (DTW) airport, fly to Luis Munoz Marin International Airport (SJU), walk to San Juan Airport, take the shuttle to Hyatt Hacienda del Mar, then drive to Isabela.
- Website
- jetblue.com
Flights from Detroit to Aguadilla via Fort Lauderdale
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $130–650
Flights from Detroit to Aguadilla via New York JFK
- Ave. Duration
- 8h 50m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $130–600
Flights from Detroit to Eugenio María De Hostos Airport via Luis Munoz Marin International Airport
- Ave. Duration
- 8h 52m
- When
- Every day
- Estimated price
- $80–370
Flights from Detroit to Eugenio María De Hostos Airport via Raleigh/Durham, Luis Munoz Marin International Airport
- Ave. Duration
- 10h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–370
Flights from Detroit to Eugenio María De Hostos Airport via Washington Dulles, Luis Munoz Marin International Airport
- Ave. Duration
- 12h 43m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–380
Flights from Detroit to Ponce via Orlando
- Ave. Duration
- 11h 20m
- When
- Every day
- Estimated price
- $140–650
Flights from Detroit to Ponce via Covington, Orlando
- Ave. Duration
- 18h 47m
- When
- Every day
- Estimated price
- $140–650
- Website
- united.com
Flights from Detroit to Aguadilla via Newark
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $130–600
Flights from Detroit to Luis Munoz Marin International Airport via Washington Dulles
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $110–550
Flights from Detroit to Eugenio María De Hostos Airport via Luis Munoz Marin International Airport
- Ave. Duration
- 7h 36m
- When
- Every day
- Estimated price
- $80–370
Flights from Detroit to Eugenio María De Hostos Airport via Washington Dulles, Luis Munoz Marin International Airport
- Ave. Duration
- 10h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–380
- Website
- flyfrontier.com
Flights from Detroit to Aguadilla via Orlando
- Ave. Duration
- 11h 17m
- When
- Every day
- Estimated price
- $130–600
Flights from Detroit to Ponce via Orlando
- Ave. Duration
- 23h
- When
- Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $140–650
Flights from Detroit to Ponce via Cleveland, Orlando
- Ave. Duration
- 16h 31m
- When
- Thursday
- Estimated price
- $140–650
- Website
- southwest.com
Flights from Detroit to Luis Munoz Marin International Airport via Baltimore
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $120–550
- Website
- capeair.com
Flights from Detroit to Eugenio María De Hostos Airport via Luis Munoz Marin International Airport
- Ave. Duration
- 8h 52m
- When
- Every day
- Estimated price
- $80–370
Flights from Detroit to Eugenio María De Hostos Airport via Washington Dulles, Luis Munoz Marin International Airport
- Ave. Duration
- 12h 43m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–380
- Website
- delta.com
Flights from Detroit to Luis Munoz Marin International Airport
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $110–550
- Phone
- +1 517-333-0400
- info@michiganflyer.com
- Website
- michiganflyer.com
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
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