There are 7 ways to get from Ann Arbor to Buffalo–Depew Station by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Buffalo  •  4 h 21 min

  1. Fly from Detroit (DTW) to Buffalo (BUF) DTW - BUF

$140 - $482

Cheapest option

Bus, Thru-Bus  •  11 h 23 min

  1. Take the bus from Ann Arbor, Mi to Detroit, Mi
  2. Take the bus from Detroit, Mi to Hamilton, On
  3. Take the Thru-Bus from Hamilton, ON to Buffalo, NY

$52 - $122

5 alternative options

Fly to Rochester, train  •  5 h 43 min

  1. Fly from Detroit (DTW) to Rochester (ROC) DTW - ROC
  2. Take the train from Rochester to Buffalo

$193 - $461

Bus, train Amtrak  •  8 h 32 min

  1. Take the bus from Ann Arbor, Mi to Detroit, Mi
  2. Take the bus from Detroit, Mi to Toledo, Oh
  3. Take the train from Toledo Amtrak to Buffalo Depew Station Amtrak

$73 - $191

Train, Amtrak Thruway  •  9 h 23 min

  1. Take the train from Ann Arbor Amtrak to Detroit Amtrak
  2. Take the Amtrak Thruway from Detroit, MI - Amtrak to Toledo, OH Amtrak
  3. Take the train from Toledo Amtrak to Buffalo Depew Station Amtrak

Bus, train via London  •  11 h 17 min

  1. Take the bus from Ann Arbor, Mi to London, On
  2. Take the train from London to Aldershot
  3. Take the train from Aldershot to Buffalo

$74 - $202

Drive  •  5 h 36 min

  1. Drive from Ann Arbor to Buffalo–Depew Station 310.8 miles

$30 - $45

Questions & Answers

No, there is no direct bus from Ann Arbor to Buffalo–Depew Station. However, there are services departing from Ann Arbor, Mi and arriving at Walden Ave & 2929 Walden via Detroit, Mi, Hamilton, ON, Ellicott St & North Division St and Galleria Drway & Green Parking Entrance. The journey, including transfers, takes approximately 11 h 23 min.

More details

The distance between Ann Arbor and Buffalo–Depew Station is 260 miles. The road distance is 310.8 miles.

Get driving directions

The best way to get from Ann Arbor to Buffalo–Depew Station without a car is to bus and train which takes 8 h 32 min and costs .

More details

It takes approximately 4 h 21 min to get from Ann Arbor to Buffalo–Depew Station, including transfers.

More details

Ann Arbor to Buffalo–Depew Station bus services, operated by Greyhound USA, depart from Ann Arbor, Mi station.

More details

The best way to get from Ann Arbor to Buffalo–Depew Station is to fly which takes 4 h 21 min and costs . Alternatively, you can bus and Thru-Bus, which costs and takes 11 h 23 min.

Mode details

The quickest flight from Detroit Airport to Buffalo Airport is the direct flight which takes 1 h 2 min.

Search flights

Ann Arbor to Buffalo–Depew Station bus services, operated by Greyhound Canada, arrive at Buffalo, NY station.

More details

Yes, the driving distance between Ann Arbor to Buffalo–Depew Station is 311 miles. It takes approximately 5 h 36 min to drive from Ann Arbor to Buffalo–Depew Station.

Get driving directions

Delta offers flights from Detroit Airport to Buffalo Airport.

Search flights

Map of how to get from Ann Arbor to Buffalo–Depew Station.
Launch map view
  • Distance: 260.2 miles
  • Duration: 4 h 21 min

What companies run services between Ann Arbor, MI, USA and Buffalo–Depew Station, NY, USA?

Delta flies from Ann Arbor to Buffalo–Depew Station 5 times a day. Alternatively, you can take a bus from Ann Arbor to Buffalo–Depew Station via Detroit, Mi, Hamilton, On, Hamilton, ON, Buffalo, NY, Ellicott St & North Division St, Galleria Drway & Green Parking Entrance, and Walden Ave & 2929 Walden in around 11 h 23 min.

Airlines
Delta
Website
delta.com
Flights from Detroit to Buffalo
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$240 - $700
Flights from Detroit to Rochester
Ave. Duration
1 h 13 min
When
Every day
Estimated price
$320 - $750
Air Canada
Website
aircanada.com
Flights from Detroit to Rochester via Toronto
Ave. Duration
3 h 19 min
When
Every day
Estimated price
$180 - $800
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Rochester to Buffalo
Ave. Duration
1 h 9 min
Frequency
Every 3 hours
Estimated price
$24 - $70
Website
viarail.ca
Escape
$24 - $35
Economy
$30 - $45
Economy Plus
$45 - $70
Business
$40 - $60
Business Plus/Sleeper
$75 - $110
Train from London to Aldershot
Ave. Duration
1 h 26 min
Frequency
Every 30 minutes
Estimated price
$26 - $75
Website
viarail.ca
Escape
$26 - $40
Economy
$30 - $50
Economy Plus
$50 - $75
Business
$45 - $70
Business Plus/Sleeper
$85 - $130
Train from Aldershot to Buffalo
Ave. Duration
4 h 2 min
Frequency
Every 3 hours
Estimated price
$26 - $75
Website
viarail.ca
Escape
$26 - $40
Economy
$30 - $50
Economy Plus
$55 - $75
Business
$45 - $70
Business Plus/Sleeper
$85 - $130
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Rochester Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
1 h
Frequency
5 times a day
Estimated price
$25 - $50
Website
amtrak.com
Coach Seat
$25 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from Toledo Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
5 h 26 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $140
Business Coach Seat
$95 - $140
Room
$240 - $330
Train from Ann Arbor Amtrak to Detroit Amtrak
Ave. Duration
52 min
Frequency
3 times a day
Estimated price
$22 - $45
Website
amtrak.com
Coach Seat
$22 - $35
Flexi Coach Seat
$40 - $60
Business Coach Seat
$30 - $45
Room
$130 - $190
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ann Arbor, Mi to Detroit, Mi
Ave. Duration
50 min
Frequency
Every 30 minutes
Estimated price
$11 - $24
Website
greyhound.com
Economy
$11 - $16
Flexible
$18 - $24
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1 h 10 min
Frequency
Every 15 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28
Bus from Ann Arbor, Mi to London, On
Ave. Duration
4 h 20 min
Frequency
Hourly
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Detroit, Mi to Hamilton, On
Ave. Duration
4 h 5 min
Frequency
Every 4 hours
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Detroit, MI - Amtrak to Toledo, OH Amtrak
Ave. Duration
1 h 5 min
Frequency
Once daily
Website
amtrak.com
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Hamilton, ON to Buffalo, NY
Ave. Duration
2 h 40 min
Frequency
Once daily
Estimated price
$12 - $35
Website
Greyhound.ca
Advanced Purchase
$12 - $18
Online Fare
$13 - $27
Standard Fare
$21 - $35
Refundable
$25 - $40

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There are 130+ hotels available in Buffalo–Depew Station. Prices start at $65 USD per night.

More details

The best way to get from Ann Arbor to Detroit Airport is to bus which takes 35 min and costs .

More details