There are 9 ways to get from Ann Arbor to Buffalo–Depew Station by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Buffalo  •  4 h 25 min

  1. Fly from Detroit (DTW) to Buffalo (BUF) DTW - BUF

$140 - $482

Cheapest option

Bus, Thru-Bus  •  11 h 26 min

  1. Take the bus from Ann Arbor, Mi to Detroit, Mi
  2. Take the bus from Detroit, Mi to Hamilton, On
  3. Take the Thru-Bus from Hamilton, ON to Buffalo, NY

$52 - $117

7 alternative options

Fly to Rochester, train  •  5 h 23 min

  1. Fly from Detroit (DTW) to Rochester (ROC) DTW - ROC
  2. Take the train from Rochester Amtrak to Buffalo Depew Station Amtrak

$194 - $441

Fly to Erie, train  •  5 h 6 min

  1. Fly from Detroit (DTW) to Erie (ERI) DTW - ERI
  2. Take the train from Erie Amtrak to Buffalo Depew Station Amtrak

$233 - $1,107

Bus, train Amtrak  •  8 h 32 min

  1. Take the bus from Ann Arbor, Mi to Detroit, Mi
  2. Take the bus from Detroit, Mi to Toledo, Oh
  3. Take the train from Toledo Amtrak to Buffalo Depew Station Amtrak

$73 - $191

Amtrak Thruway, train  •  8 h 36 min

  1. Take the Amtrak Thruway from Ann Arbor, MI - Amtrak to Toledo, OH Amtrak 8150 / ...
  2. Take the train from Toledo Amtrak to Buffalo Depew Station Amtrak Lake Shore Limited

$50 - $140

Train  •  9 h 14 min

  1. Take the train from Ann Arbor Amtrak to Detroit Amtrak
  2. Take the train from Windsor to Aldershot
  3. Take the train from Aldershot to Niagara Falls Station
  4. Take the train from Niagara Falls Station to Buffalo

$102 - $289

Bus, train via Aldershot GO Bus  •  10 h 50 min

  1. Take the bus from Ann Arbor, Mi to Hamilton, On 5500
  2. Take the train from Aldershot to Buffalo VIA Rail

$59 - $149

Drive  •  5 h 36 min

  1. Drive from Ann Arbor to Buffalo–Depew Station 310.8 miles

$30 - $45

Questions & Answers

The cheapest way to get from Ann Arbor to Buffalo–Depew Station is to drive which costs $30 - $45 and takes 5 h 36 min.

More details

The quickest way to get from Ann Arbor to Buffalo–Depew Station is to fly which costs $140 - $490 and takes 4 h 25 min.

More details

The distance between Ann Arbor and Buffalo–Depew Station is 260 miles. The road distance is 310.8 miles.

Get driving directions

It takes approximately 4 h 25 min to get from Ann Arbor to Buffalo–Depew Station, including transfers.

More details

No, there is no direct bus from Ann Arbor to Buffalo–Depew Station. However, there are services departing from Ann Arbor, Mi and arriving at Walden Ave & 2929 Walden via Detroit, Mi, Hamilton, ON, Ellicott St & North Division St and Galleria Drway & Green Parking Entrance. The journey, including transfers, takes approximately 11 h 26 min.

More details

What companies run services between Ann Arbor, MI, USA and Buffalo–Depew Station, NY, USA?

Delta flies from Ann Arbor to Buffalo–Depew Station 5 times a day. Alternatively, you can take a train from Ann Arbor to Buffalo–Depew Station via Detroit Amtrak, Windsor, Aldershot, and Niagara Falls Station in around 9 h 14 min.

Airlines
Delta
Website
delta.com
Flights from Detroit to Buffalo
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$240 - $700
Flights from Detroit to Rochester
Ave. Duration
1 h 18 min
When
Every day
Estimated price
$320 - $750
Flights from Detroit to Erie
Ave. Duration
56 min
When
Every day
Estimated price
$170 - $1,000
Air Canada
Website
aircanada.com
Flights from Detroit to Rochester via Toronto
Ave. Duration
3 h 14 min
When
Every day
Estimated price
$180 - $800
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Rochester Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
46 min
Frequency
Every 4 hours
Estimated price
$25 - $50
Website
amtrak.com
Coach Seat
$25 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from Erie Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
1 h 26 min
Frequency
Twice daily
Estimated price
$29 - $65
Website
amtrak.com
Coach Seat
$29 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$40 - $65
Room
$150 - $220
Train from Toledo Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
5 h 26 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $140
Business Coach Seat
$95 - $140
Room
$240 - $330
Train from Ann Arbor Amtrak to Detroit Amtrak
Ave. Duration
52 min
Frequency
3 times a day
Estimated price
$22 - $45
Website
amtrak.com
Coach Seat
$22 - $35
Flexi Coach Seat
$40 - $60
Business Coach Seat
$30 - $45
Room
$130 - $190
Train from Niagara Falls Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
48 min
Frequency
4 times a day
Estimated price
$22 - $45
Website
amtrak.com
Coach Seat
$22 - $35
Flexi Coach Seat
$35 - $60
Business Coach Seat
$29 - $45
Room
$130 - $190
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Rochester to Buffalo
Ave. Duration
1 h 4 min
Frequency
Every 3 hours
Estimated price
$23 - $70
Website
viarail.ca
Escape
$23 - $35
Economy
$30 - $40
Economy Plus
$45 - $70
Business
$40 - $60
Business Plus/Sleeper
$75 - $110
Train from Windsor to Aldershot
Ave. Duration
3 h 24 min
Frequency
Hourly
Estimated price
$35 - $120
Website
viarail.ca
Escape
$35 - $50
Economy
$55 - $75
Economy Plus
$80 - $120
Business
$75 - $110
Business Plus/Sleeper
$140 - $200
Train from Aldershot to Niagara Falls Station
Ave. Duration
1 h 37 min
Frequency
Every 3 hours
Estimated price
$22 - $65
Website
viarail.ca
Escape
$22 - $35
Economy
$27 - $40
Economy Plus
$45 - $65
Business
$35 - $55
Business Plus/Sleeper
$70 - $100
Train from Niagara Falls Station to Buffalo
Ave. Duration
52 min
Frequency
Every 3 hours
Estimated price
$21 - $60
Website
viarail.ca
Escape
$21 - $30
Economy
$24 - $35
Economy Plus
$40 - $60
Business
$30 - $50
Business Plus/Sleeper
$60 - $90
Train from Aldershot to Buffalo
Ave. Duration
3 h 32 min
Frequency
Every 3 hours
Estimated price
$26 - $75
Website
viarail.ca
Escape
$26 - $40
Economy
$30 - $50
Economy Plus
$50 - $75
Business
$45 - $70
Business Plus/Sleeper
$85 - $130
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ann Arbor, Mi to Detroit, Mi
Ave. Duration
50 min
Frequency
Hourly
Estimated price
$11 - $24
Website
greyhound.com
Economy
$11 - $16
Flexible
$18 - $24
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1 h 10 min
Frequency
Every 15 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28
Bus from Ann Arbor, Mi to Hamilton, On
Ave. Duration
5 h 45 min
Frequency
Every 4 hours
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from Detroit, Mi to Hamilton, On
Ave. Duration
4 h 5 min
Frequency
Every 4 hours
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Hamilton, ON to Buffalo, NY
Ave. Duration
2 h 40 min
Frequency
Once daily
Estimated price
$12 - $30
Website
Greyhound.ca
Advanced Purchase
$12 - $17
Online Fare
$13 - $27
Standard Fare
$21 - $30
Refundable
$24 - $35

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