From Amsterdam Centraal train to Amersfoort then train to Enschede. 2 h 9 min 32€. From Amsterdam drive to Enschede. 1 h 38 min 25€.
Train from Amsterdam to Overijssel
Dutch Railways (NS) operates a train from Amsterdam to Enschede every 30 minutes. Tickets cost $8 - $16 and the journey takes 34 min. Dutch Railways (NS) also services this route every 30 minutes.