There are 4 ways to get from Ames to St. Louis by bus (Greyhound), car, shuttle, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Ames to Des Moinesbus Jefferson 801 / ...
- Take the bus from Des Moines to St Louis Bus Stationbus Greyhound US0153S
10h$85–157Drive 360.9 mi
cheapest- Drive from Ames to St. Louiscar 360.9 mi
7h 8m$66–96Shuttle to Des Moines, fly
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
6h 8m$215–993Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Ames to MSP Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane MSP - STL
7h 4m$170–782
Ames to St. Louis by bus
Questions & Answers
The cheapest way to get from Ames to St. Louis is to drive which costs $65 - $95 and takes 7h 8m.
The fastest way to get from Ames to St. Louis is to shuttle and fly which takes 6h 8m and costs $210 - $1,000.
No, there is no direct bus from Ames to St. Louis station. However, there are services departing from Ames and arriving at St Louis Bus Station via Des Moines. The journey, including transfers, takes approximately 10h.
The distance between Ames and St. Louis is 450 miles. The road distance is 363 miles.
The best way to get from Ames to St. Louis without a car is to bus which takes 10h and costs $80 - $160.
It takes approximately 10h to get from Ames to St. Louis, including transfers.
Ames to St. Louis bus services, operated by Jefferson Lines, depart from Ames station.
Ames to St. Louis bus services, operated by Jefferson Lines, arrive at Des Moines station.
Yes, the driving distance between Ames to St. Louis is 363 miles. It takes approximately 7h 8m to drive from Ames to St. Louis.
There are 373+ hotels available in St. Louis.
What companies run services between Ames, IA, USA and St. Louis, MO, USA?
You can take a bus from Ames to St Louis Bus Station via Des Moines in around 10h.
- Website
- aa.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $130–800
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- united.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $130–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 23m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $260–1,200
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 3h 59m
- When
- Tuesday and Wednesday
- Estimated price
- $130–800
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–850
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $110–700
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 37m
- When
- Monday to Friday
- Estimated price
- $130–800
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $110–700
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–800
- Website
- flyfrontier.com
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 7m
- When
- Monday and Friday
- Estimated price
- $260–1,200
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $19–27
- Book at
- https://www.jeffersonlines.com
- Adult
- $19–27
Bus from Ames to MSP Airport
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $55–80
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–80
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
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