There are 5 ways to get from Ames to St. Louis by shuttle, plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle, fly
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
3h 38m$205–993Bus via Kansas City
cheapest- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
10h 15m$56–201Bus, train
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
12h 36m$56–196Drive 360.9 mi
- Drive from Ames to St. Louiscar 360.9 mi
7h 6m$66–96Bus
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Mt. Pleasantbus
- Take the bus from Mt. Pleasant to St Louisbus
11h 35m$102–257
Ames to St. Louis by bus
Questions & Answers
The cheapest way to get from Ames to St. Louis is to drive which costs $65 - $95 and takes 7h 6m.
The fastest way to get from Ames to St. Louis is to shuttle and fly which takes 3h 38m and costs $200 - $1,000.
No, there is no direct bus from Ames to St. Louis station. However, there are services departing from Ames and arriving at St Louis Bus Station via Des Moines and Kansas City Bus Station. The journey, including transfers, takes approximately 10h 15m.
The distance between Ames and St. Louis is 316 miles. The road distance is 363 miles.
The best way to get from Ames to St. Louis without a car is to bus via Kansas City which takes 10h 15m and costs $55 - $210.
It takes approximately 3h 38m to get from Ames to St. Louis, including transfers.
Ames to St. Louis bus services, operated by Jefferson Lines, depart from Ames station.
Ames to St. Louis bus services, operated by Jefferson Lines, arrive at Des Moines station.
Yes, the driving distance between Ames to St. Louis is 363 miles. It takes approximately 7h 6m to drive from Ames to St. Louis.
There are 392+ hotels available in St. Louis.
What companies run services between Ames, IA, USA and St. Louis, MO, USA?
You can take a bus from Ames to St Louis Bus Station via Des Moines and Kansas City Bus Station in around 10h 15m.
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $120–800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $35–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $3–45
- Book at
- https://www.jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Mt. Pleasant
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://burlingtontrailways.com
- Saver Fares
- $35–55
- Flexible Fares
- $50–75
Bus from Mt. Pleasant to St Louis
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $55–128
- Website
- https://burlingtontrailways.com
- Saver Fares
- $55–80
- Flexible Fares
- $70–110
- Saver Fare
- $92
- Flex Fare
- $128
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