There are 5 ways to get from Ames to St. Louis by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 31 min

  1. Fly from Des Moines (DSM) to St. Louis (STL) DSM - STL

$222 - $943

Cheapest option

Bus Greyhound USA  •  8 h 53 min

  1. Take the bus from Ames, IA to Kansas City, MO 803 / ...
  2. Take the bus from Kansas City, Mo to St Louis, Mo 1682 / ...

$75 - $133

3 alternative options

Bus, train  •  11 h 31 min

  1. Take the bus from Ames, IA to Des Moines, IA 801 / ...
  2. Take the bus from Des Moines, IA to Kansas City, MO 803 / ...
  3. Take the train from Kansas City Amtrak to St. Louis Gateway Station Amtrak

$110 - $222

Bus Burlington Trailways  •  12 h 45 min

  1. Take the bus from Ames, IA to Cedar Rapids 1486
  2. Take the bus from Cedar Rapids to St Louis, MO 1490

$86 - $143

Drive  •  6 h 56 min

  1. Drive from Ames to St. Louis 381.4 miles

$35 - $55

Questions & Answers

The cheapest way to get from Ames to St. Louis is to drive which costs $35 - $55 and takes 6 h 56 min.

More details

The quickest way to get from Ames to St. Louis is to fly which costs $220 - $950 and takes 3 h 31 min.

More details

The distance between Ames and St. Louis is 298 miles. The road distance is 381.4 miles.

Get driving directions

It takes approximately 3 h 31 min to get from Ames to St. Louis, including transfers.

More details

No, there is no direct bus from Ames to St. Louis. However, there are services departing from Ames, IA and arriving at St Louis, Mo via Kansas City, Mo. The journey, including transfers, takes approximately 8 h 53 min.

More details

What companies run services between Ames, IA, USA and St. Louis, MO, USA?

Southwest Airlines flies from Ames to St. Louis twice daily. Alternatively, you can take a bus from Ames to St. Louis via Kansas City, MO and Kansas City, Mo in around 8 h 53 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Des Moines to St. Louis
Ave. Duration
56 min
When
Every day
Estimated price
$190 - $900
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kansas City Amtrak to St. Louis Gateway Station Amtrak
Ave. Duration
5 h 40 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Ames, IA to Kansas City, MO
Ave. Duration
4 h 25 min
Frequency
Hourly
Estimated price
$45 - $65
Schedules at
jeffersonlines.com
Bus from Ames, IA to Des Moines, IA
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$15 - $22
Schedules at
jeffersonlines.com
Bus from Des Moines, IA to Kansas City, MO
Ave. Duration
3 h 10 min
Frequency
Hourly
Estimated price
$40 - $55
Schedules at
jeffersonlines.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Burlington Trailways
Website
burlingtontrailways.com
Bus from Ames, IA to Des Moines, IA
Ave. Duration
45 min
Frequency
Once a week
Estimated price
$23 - $35
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Ames, IA to Cedar Rapids
Ave. Duration
2 h 30 min
Frequency
Once daily
Estimated price
$30 - $45
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Cedar Rapids to St Louis, MO
Ave. Duration
9 h 15 min
Frequency
Once daily
Estimated price
$55 - $100
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com

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