What is the cheapest way to get from Ames to St. Louis?

The cheapest way to get from Ames to St. Louis is to drive which costs $65 - $95 and takes 7h 8m.

What is the fastest way to get from Ames to St. Louis?

The fastest way to get from Ames to St. Louis is to shuttle and fly which takes 5h 48m and costs $230 - $1,100.

Is there a direct bus between Ames and St. Louis?

No, there is no direct bus from Ames to St. Louis station. However, there are services departing from Ames and arriving at St Louis Bus Station via Des Moines. The journey, including transfers, takes approximately 10h.

How far is it from Ames to St. Louis?

The distance between Ames and St. Louis is 316 miles. The road distance is 363 miles.

How do I travel from Ames to St. Louis without a car?

The best way to get from Ames to St. Louis without a car is to bus which takes 10h and costs $75 - $150.

How long does it take to get from Ames to St. Louis?

It takes approximately 5h 48m to get from Ames to St. Louis, including transfers.

Where do I catch the Ames to St. Louis bus from?

Ames to St. Louis bus services, operated by Jefferson Lines, depart from Ames station.

Where does the Ames to St. Louis bus arrive?

Ames to St. Louis bus services, operated by Jefferson Lines, arrive at Des Moines station.

Can I drive from Ames to St. Louis?

Yes, the driving distance between Ames to St. Louis is 363 miles. It takes approximately 7h 8m to drive from Ames to St. Louis.

How do I get a bus ticket from Ames to St. Louis?

Book your Ames to St. Louis bus tickets online with Omio.

Where can I stay near St. Louis?

There are 533+ hotels available in St. Louis.

Ames to St. Louis - 4 ways to travel via shuttle, plane, bus, and car

How to get fromAmes to St. Louis

Travel from

See all options

Search accommodation with Expedia

There are 4 ways to get from Ames to St. Louis by shuttle, plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Shuttle to Des Moines, fly
best
1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle
2. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
5h 48m
$235–1,043
Drive 360.9 mi
cheapest
1. Drive from Ames to St. Louiscar 360.9 mi
7h 8m
$66–96
Bus
1. Take the bus from Ames to Des Moinesbus Jefferson 801 / ...
2. Take the bus from Des Moines to St Louis Bus Stationbus Greyhound US0153S
10h
$80–147
Bus to Minneapolis–Saint Paul International Airport, fly
1. Take the bus from Ames to MSP Airportbus
2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane MSP - STL
6h 59m
$440–1,032

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

105Weekly Planes

4h 42mAverage Duration

$150Cheapest Price

See schedules

Questions & Answers

Map of how to get from Ames to St. Louis.

Launch map view

Distance: 314.6 mi
Duration: 5h 48m

What companies run services between Ames, IA, USA and St. Louis, MO, USA?

You can take a bus from Ames to St Louis Bus Station via Des Moines in around 10h.

Airlines

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Travelling to the US: What do I need to know?

Rome2Rio’s travel guides to the US tell you the best ways to explore the country, from Amtrak to Greyhound to the New York Subway.

Read the travel guide Travelling to the US: What do I need to know?

Need to know: Greyhound

Rome2Rio’s guide on the bus operator has all the information you need

Read the travel guide Need to know: Greyhound

How to get fromAmes to St. Louisby shuttle, plane, bus (Greyhound), car, or bus

There are 4 ways to get from Ames to St. Louis by shuttle, plane, bus (Greyhound), car, or bus

Shuttle to Des Moines, fly

Drive 360.9 mi

Bus

Bus to Minneapolis–Saint Paul International Airport, fly