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How to get fromAmes to Lexingtonby shuttle, plane, car, taxi, or bus

Find Transport to Lexington

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There are 7 ways to get from Ames to Lexington by shuttle, plane, car, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Des Moines, fly to Louisville International Airport, drive

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 29m
    $236–1,011

  2. Bus to Mason City, fly to Blue Grass Airport

    cheapest
    1. Take the bus from Ames to Mason Citybus bus
    2. Fly from Mason City (MCW) to Blue Grass Airport (LEX)plane plane MCW - LEX
    11h 3m
    $98–425

  3. Taxi, bus, drive

    1. Take the taxi from Ames to Des Moinestaxi taxi
    2. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    16h 43m
    $181–277

  4. Drive  658.4 mi

    1. Drive from Ames to Lexingtoncar car 658.4 mi
    11h 48m
    $121–174

  5. Shuttle to Des Moines, fly to Covington, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    3. Drive from Covington (CVG) to Lexingtoncar car
    6h 36m
    $227–1,012

  6. Shuttle to Des Moines, fly to Blue Grass Airport

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    8h 26m
    $169–682

  7. Taxi to Fort Dodge Municipal Airport, fly to Blue Grass Airport

    1. Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi taxi
    2. Fly from Fort Dodge Municipal Airport (FOD) to Blue Grass Airport (LEX)plane plane FOD - LEX
    8h 41m
    $217–563

Des Moines (DSM) to Louisville International Airport (SDF) flights

Calendar114Weekly Planes
Duration4h 56mAverage Duration
Ticket$141Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ames to Lexington.ExpandLaunch map view
  • Distance: 599.5 mi
  • Duration: 6h 29m

What companies run services between Ames, IA, USA and Lexington, KY, USA?

There is no direct connection from Ames to Lexington. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take the taxi to Des Moines, take the bus to Indianapolis Union Station, take the bus to Louisville Bus Station, walk to Chestnut @ 13th, take the line 21 bus to Chestnut @ 8th, walk to S 5th @ W Jefferson, take the line 31 bus to Middletown Station @ Target, then drive to Lexington.

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