There are 8 ways to get from Ames to Lexington by shuttle, plane, car, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Des Moines, fly to Louisville International Airport, drive
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane DSM - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
6h 39m$216–911Bus to Mason City, fly to Blue Grass Airport
cheapest- Take the bus from Ames to Mason Citybus
- Fly from Mason City (MCW) to Blue Grass Airport (LEX)plane MCW - LEX
9h 3m$98–415Bus, drive
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
19h 19m$126–246Drive 658.6 mi
- Drive from Ames to Lexingtoncar 658.6 mi
11h 46m$121–174Taxi to Fort Dodge Municipal Airport, fly to Blue Grass Airport
- Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi
- Fly from Fort Dodge Municipal Airport (FOD) to Blue Grass Airport (LEX)plane FOD - LEX
8h 23m$212–553Shuttle to Des Moines, fly to Blue Grass Airport
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane DSM - LEX
8h 3m$164–672Bus, taxi, drive
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Paoli Walmartbus
- Take the taxi from Paoli Walmart to Indiana University Southeasttaxi
- Drive from Middletown Station @ Target to Lexingtoncar
20h 30m$244–386Bus, drive via St. Louis
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Corydon, INbus
- Drive from Middletown Station @ Target to Lexingtoncar
20h 44m$214–358
Des Moines (DSM) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Ames to Lexington is to drive which costs $120 - $180 and takes 11h 46m.
The fastest way to get from Ames to Lexington is to shuttle and fly and drive which takes 6h 39m and costs $210 - $950.
The distance between Ames and Lexington is 603 miles. The road distance is 662.4 miles.
It takes approximately 6h 39m to get from Ames to Lexington, including transfers.
Lexington is 1h ahead of Ames. It is currently 7:08 PM in Ames and 8:08 PM in Lexington.
Yes, the driving distance between Ames to Lexington is 662 miles. It takes approximately 11h 46m to drive from Ames to Lexington.
There are 450+ hotels available in Lexington.
What companies run services between Ames, IA, USA and Lexington, KY, USA?
There is no direct connection from Ames to Lexington. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take a bus from Ames to Lexington via Des Moines, Indianapolis Union Station, Louisville, KY, Roy Wilkins @ W Broadway, Chestnut @ 8th, S 5th @ W Jefferson, and Middletown Station @ Target in around 19h 19m.
- Website
- aa.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $120–700
Flights from Des Moines to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–950
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $80–480
Flights from Des Moines to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $150–700
- Website
- united.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $120–700
Flights from Fort Dodge Municipal Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $65–380
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $80–480
Flights from Mason City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $65–370
- Website
- delta.com
Flights from Des Moines to Louisville International Airport via Minneapolis
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $150–800
Flights from Des Moines to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $180–900
Flights from Des Moines to Louisville International Airport via Detroit
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $150–800
Flights from Des Moines to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $120–600
Flights from Des Moines to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–550
Flights from Des Moines to Blue Grass Airport via Minneapolis
- Ave. Duration
- 6h 59m
- When
- Saturday
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Des Moines to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 52m
- When
- Monday to Saturday
- Estimated price
- $120–700
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $19–27
- Book at
- https://www.jeffersonlines.com
- Adult
- $19–27
Bus from Ames to Mason City
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $70–150
- Website
- https://www.greyhound.com/
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Indianapolis Union Station to Paoli Walmart
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- https://ridewithmiller.com
Bus from Evansville, IN to Corydon, IN
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- https://ridewithmiller.com
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