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How to get fromAmes to Lexingtonby shuttle, plane, car, taxi, bus, or train

Find Transport to Lexington

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There are 9 ways to get from Ames to Lexington by shuttle, plane, car, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Des Moines, fly to Louisville International Airport, drive

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 44m
    $206–861

  2. Bus to Mason City, fly to Blue Grass Airport

    cheapest
    1. Take the bus from Ames to Mason Citybus bus
    2. Fly from Mason City (MCW) to Blue Grass Airport (LEX)plane plane MCW - LEX
    8h 58m
    $98–425

  3. Taxi, bus, drive

    1. Take the taxi from Ames to Des Moinestaxi taxi
    2. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    17h 24m
    $191–277

  4. Drive  658.1 mi

    1. Drive from Ames to Lexingtoncar car 658.1 mi
    11h 49m
    $121–174

  5. Shuttle to Des Moines, fly to Blue Grass Airport

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    8h 8m
    $149–572

  6. Taxi to Fort Dodge Municipal Airport, fly to Blue Grass Airport

    1. Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi taxi
    2. Fly from Fort Dodge Municipal Airport (FOD) to Blue Grass Airport (LEX)plane plane FOD - LEX
    8h 29m
    $217–563

  7. Bus, drive

    1. Take the bus from Ames to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    20h 24m
    $231–392

  8. Shuttle, bus, taxi, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Paoli Walmartbus bus
    4. Take the taxi from Paoli Walmart to Indiana University Southeasttaxi taxi
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    20h 31m
    $340–603

  9. Bus, train, drive

    1. Take the bus from Ames to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    22h 44m
    $341–567

Des Moines (DSM) to Louisville International Airport (SDF) flights

Calendar110Weekly Planes
Duration5h 15mAverage Duration
Ticket$116Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ames to Lexington.ExpandLaunch map view
  • Distance: 599.5 mi
  • Duration: 6h 44m

What companies run services between Ames, IA, USA and Lexington, KY, USA?

There is no direct connection from Ames to Lexington. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take the taxi to Des Moines, take the bus to Indianapolis Union Station, take the bus to Louisville, KY, walk to Roy Wilkins @ W Broadway, take the line 93 bus to Chestnut @ 8th, walk to S 5th @ W Jefferson, take the line 31 bus to Middletown Station @ Target, then drive to Lexington.

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