There are 9 ways to get from Ames to Lexington by shuttle, plane, car, bus (Greyhound), bus, train, taxi, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Des Moines, fly to Louisville International Airport, drive
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane DSM - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
7h 5m$246–1,061Bus to Mason City, fly to Blue Grass Airport
cheapest- Take the bus from Ames to Mason Citybus
- Fly from Mason City (MCW) to Blue Grass Airport (LEX)plane MCW - LEX
9h 50m$75–429Bus
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Lexington Bus Stopbus
18h 57m$120–293Bus, train via Saint Paul
- Take the bus from Ames to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
23h 25m$178–478Drive 658.6 mi
- Drive from Ames to Lexingtoncar 658.6 mi
11h 46m$121–174Taxi to Fort Dodge Municipal Airport, fly to Blue Grass Airport
- Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi
- Fly from Fort Dodge Municipal Airport (FOD) to Blue Grass Airport (LEX)plane FOD - LEX
8h 40m$212–543Shuttle to Des Moines, fly to Blue Grass Airport
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane DSM - LEX
8h 27m$194–842Bus via Indianapolis
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Indianapolisbus
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
19h 47m$132–304Bus, train
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
19h 55m$140–313
Des Moines (DSM) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Ames to Lexington is to drive which costs $120 - $180 and takes 11h 46m.
The fastest way to get from Ames to Lexington is to shuttle and fly and drive which takes 7h 5m and costs $240 - $1,100.
The distance between Ames and Lexington is 603 miles. The road distance is 662.4 miles.
The best way to get from Ames to Lexington without a car is to bus which takes 18h 57m and costs $120 - $300.
It takes approximately 7h 5m to get from Ames to Lexington, including transfers.
Lexington is 1h ahead of Ames. It is currently 8:14 PM in Ames and 9:14 PM in Lexington.
Yes, the driving distance between Ames to Lexington is 662 miles. It takes approximately 11h 46m to drive from Ames to Lexington.
There are 119+ hotels available in Lexington.
What companies run services between Ames, IA, USA and Lexington, KY, USA?
You can take a bus from Ames to Lexington via Des Moines, Chicago Bus Station, and Lexington Bus Stop in around 18h 57m.
- Website
- delta.com
Flights from Des Moines to Louisville International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Tuesday and Wednesday
- Estimated price
- $180–1,000
Flights from Des Moines to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Des Moines to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–1,000
Flights from Des Moines to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $150–800
Flights from Des Moines to Blue Grass Airport via Detroit
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $130–700
- Website
- aa.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $150–900
Flights from Des Moines to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Des Moines to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $180–900
Flights from Des Moines to Blue Grass Airport via Charlotte
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $150–800
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $110–650
- Website
- united.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $150–900
Flights from Fort Dodge Municipal Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $65–370
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $110–650
Flights from Mason City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 17m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–370
- Website
- southwest.com
Flights from Des Moines to Louisville International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 24m
- Frequency
- 3 times a day
- Estimated price
- $60–210
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $3–45
- Book at
- https://www.jeffersonlines.com
Bus from Ames to St. Paul
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $20–100
- Book at
- https://www.jeffersonlines.com
Bus from Ames to Mason City
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $8–60
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–100
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Lexington Bus Stop
- Ave. Duration
- 8h 55m
- Frequency
- 4 times a week
- Estimated price
- $50–120
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- 4 times a week
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 50m
- Frequency
- Every 4 hours
- Estimated price
- $35–70
- Schedules at
- flixbus.com
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