There are 6 ways to get from Ames to Lexington by shuttle, plane, car, bus (Greyhound), taxi, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Des Moines, fly to Louisville International Airport, drive
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane DSM - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
7h 5m$246–1,061Bus to Mason City, fly to Blue Grass Airport
cheapest- Take the bus from Ames to Mason Citybus
- Fly from Mason City (MCW) to Blue Grass Airport (LEX)plane MCW - LEX
9h 50m$75–429Bus
- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
16h 22m$149–329Drive 658.6 mi
- Drive from Ames to Lexingtoncar 658.6 mi
11h 40m$121–174Taxi to Fort Dodge Municipal Airport, fly to Blue Grass Airport
- Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi
- Fly from Fort Dodge Municipal Airport (FOD) to Blue Grass Airport (LEX)plane FOD - LEX
8h 39m$212–543Shuttle to Des Moines, fly to Blue Grass Airport
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane DSM - LEX
8h 27m$194–842
Des Moines (DSM) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Ames to Lexington is to drive which costs $120 - $180 and takes 11h 40m.
The fastest way to get from Ames to Lexington is to shuttle and fly and drive which takes 7h 5m and costs $240 - $1,100.
The distance between Ames and Lexington is 603 miles. The road distance is 662.4 miles.
The best way to get from Ames to Lexington without a car is to bus which takes 16h 22m and costs $140 - $330.
It takes approximately 7h 5m to get from Ames to Lexington, including transfers.
Lexington is 1h ahead of Ames. It is currently 5:23 PM in Ames and 6:23 PM in Lexington.
Yes, the driving distance between Ames to Lexington is 662 miles. It takes approximately 11h 40m to drive from Ames to Lexington.
There are 123+ hotels available in Lexington.
What companies run services between Ames, IA, USA and Lexington, KY, USA?
You can take a bus from Ames to Lexington via Des Moines, Des Moines, Indianapolis Union Station, and Lexington Bus Stop in around 16h 22m.
- Website
- delta.com
Flights from Des Moines to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,000
Flights from Des Moines to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Des Moines to Louisville International Airport via Detroit
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Des Moines to Blue Grass Airport via Atlanta
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $150–800
Flights from Des Moines to Blue Grass Airport via Detroit
- Ave. Duration
- 8h 53m
- When
- Every day
- Estimated price
- $130–700
- Website
- aa.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $150–900
Flights from Des Moines to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 24m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,100
Flights from Des Moines to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $190–900
Flights from Des Moines to Blue Grass Airport via Charlotte
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $160–800
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
- Website
- united.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $150–900
Flights from Fort Dodge Municipal Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $65–370
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $110–650
Flights from Mason City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 17m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–370
- Website
- southwest.com
Flights from Des Moines to Louisville International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Thursday and Friday
- Estimated price
- $150–850
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $3–45
- Book at
- https://www.jeffersonlines.com
Bus from Ames to Mason City
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $8–60
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $80–120
- Flexible Fares
- $110–160
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $30–85
- Website
- https://www.greyhound.com/
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