Rome2Rio

How to get fromAmes to Lexingtonby shuttle, plane, car, taxi, bus, or train

Find Transport to Lexington

See all options

There are 10 ways to get from Ames to Lexington by shuttle, plane, car, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Des Moines, fly to Covington, drive

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    3. Drive from Covington (CVG) to Lexingtoncar car
    6h 41m
    $247–1,062

  2. Drive 658.4 mi

    cheapest
    1. Drive from Ames to Lexingtoncar car 658.4 mi
    11h 48m
    $121–174

  3. Taxi, bus, drive

    1. Take the taxi from Ames to Des Moinestaxi taxi
    2. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    18h 9m
    $181–297

  4. Shuttle to Des Moines, fly to Louisville International Airport, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 49m
    $236–1,011

  5. Taxi to Fort Dodge Municipal Airport, fly to Blue Grass Airport

    1. Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)taxi taxi
    2. Fly from Fort Dodge Municipal Airport (FOD) to Blue Grass Airport (LEX)plane plane FOD - LEX
    9h 23m
    $297–973

  6. Shuttle to Des Moines, fly to Blue Grass Airport

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    8h 25m
    $304–1,392

  7. Bus to Mason City, fly to Blue Grass Airport

    1. Take the bus from Ames to Mason Citybus bus
    2. Fly from Mason City (MCW) to Blue Grass Airport (LEX)plane plane MCW - LEX
    12h 13m
    $173–845

  8. Bus, drive

    1. Take the bus from Ames to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    20h 24m
    $222–352

  9. Shuttle, bus, taxi, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Paoli Walmartbus bus
    4. Take the taxi from Paoli Walmart to Indiana University Southeasttaxi taxi
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    20h 47m
    $329–567

  10. Bus, train, drive

    1. Take the bus from Ames to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    22h 44m
    $272–467

Des Moines (DSM) to Covington (CVG) flights

Calendar123Weekly Planes
Duration5h 2mAverage Duration
Ticket$152Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Ames to Lexington.ExpandLaunch map view
  • Distance: 626.7 mi
  • Duration: 6h 41m

What companies run services between Ames, IA, USA and Lexington, KY, USA?

There is no direct connection from Ames to Lexington. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Covington (CVG), then drive to Lexington. Alternatively, you can take the taxi to Des Moines, take the bus to Indianapolis Union Station, take the bus to Louisville, KY, walk to Roy Wilkins @ W Broadway, take the line 93 bus to Chestnut @ 8th, walk to S 5th @ W Jefferson, take the line 31 bus to Middletown Station @ Target, then drive to Lexington.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound