There are 6 ways to get from Ames to Florida Keys by shuttle, plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle, fly to Key West International Airport
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Key West International Airport (EYW)plane DSM - EYW
10h 9m$369–1,459Bus, train
cheapest- Take the bus from Ames to Des Moinesbus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
2d 14h$262–744Drive 1,695 mi
- Drive from Ames to Florida Keyscar 1,695 mi
30h 25m$310–447Shuttle, fly to Miami International Airport
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Miami International Airport (MIA)plane DSM - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 45m$384–1,224Shuttle, fly to Fort Lauderdale–Hollywood International Airport
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Fort Lauderdale–Hollywood International Airport (FLL)plane DSM - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
11h 3m$354–1,044Bus, train via Saint Paul
- Take the bus from Ames to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
2d 18h$295–894
Ames to Florida Keys by bus, foot, train, and taxi
Questions & Answers
The cheapest way to get from Ames to Florida Keys is to drive which costs $300 - $450 and takes 30h 25m.
The fastest way to get from Ames to Florida Keys is to shuttle and fly which takes 10h 9m and costs $360 - $1,500.
The distance between Ames and Florida Keys is 1428 miles. The road distance is 1704.8 miles.
The best way to get from Ames to Florida Keys without a car is to bus and train which takes 2 days 14h and costs $260 - $750.
It takes approximately 10h 9m to get from Ames to Florida Keys, including transfers.
Yes, the driving distance between Ames to Florida Keys is 1705 miles. It takes approximately 30h 25m to drive from Ames to Florida Keys.
There are 838+ hotels available in Florida Keys.
What companies run services between Ames, IA, USA and Florida Keys, FL, USA?
There is no direct connection from Ames to Florida Keys. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a bus from Ames to Florida Keys via Des Moines, Chicago Bus Station, Chicago Union Station, Miami Amtrak Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 2d 14h.
- Website
- delta.com
Flights from Des Moines to Key West International Airport via Atlanta
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Des Moines to Miami International Airport via Atlanta
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $120–650
- Website
- aa.com
Flights from Des Moines to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,200
Flights from Des Moines to Key West International Airport via Charlotte
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $260–1,300
Flights from Des Moines to Miami International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $170–850
- Website
- southwest.com
Flights from Des Moines to Miami International Airport via St. Louis
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via St. Louis
- Ave. Duration
- 5h 10m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
- Website
- allegiantair.com
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 18m
- When
- Thursday and Sunday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $170–550
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 24m
- Frequency
- 3 times a day
- Estimated price
- $55–180
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $3–45
- Book at
- https://www.jeffersonlines.com
Bus from Ames to St. Paul
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $20–100
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide









