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How to get fromAmes to Florida Keysby shuttle, plane, bus, train or car

Find Transport to Florida Keys

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There are 6 ways to get from Ames to Florida Keys by shuttle, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle, fly to Key West International Airport

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle
    2. Fly from Des Moines (DSM) to Key West International Airport (EYW)planeDSM - EYW
    10h 8m
    $349–1,359
  2. Drive 1,695 mi

    cheapest
    1. Drive from Ames to Florida Keyscar1,695 mi
    30h 9m
    $310–447
  3. Bus, train

    1. Take the bus from Ames to Des Moinesbus
    2. Take the bus from Des Moines to Chicago Bus Stationbus
    3. Take the train from Chicago Union Station to Miami Amtrak Stationtrain
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    2d 14h
    $325–864
  4. Shuttle, fly to Fort Lauderdale–Hollywood International Airport

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle
    2. Fly from Des Moines (DSM) to Fort Lauderdale–Hollywood International Airport (FLL)planeDSM - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
    10h 54m
    $354–994
  5. Shuttle, fly to Miami International Airport

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle
    2. Fly from Des Moines (DSM) to Miami International Airport (MIA)planeDSM - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    10h 45m
    $384–1,174
  6. Bus, train via Saint Paul

    1. Take the bus from Ames to St. Paulbus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Miami Amtrak Stationtrain
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    2d 18h
    $358–1,039

Ames to Florida Keys by bus, foot, train, and taxi

Calendar7Weekly Services
Duration2d 14hAverage Duration
Ticket$325Cheapest Price
See schedules

Questions & Answers

What companies run services between Ames, IA, USA and Florida Keys, FL, USA?

There is no direct connection from Ames to Florida Keys. However, you can take the shuttle to Des Moines International Airport, IA, walk to Des Moines (DSM) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a bus from Ames to Florida Keys via Des Moines, Chicago Bus Station, Chicago Union Station, Miami Amtrak Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 2d 14h.

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