There are 8 ways to get from Ames to Buffalo by shuttle, plane, bus, train, bus (Greyhound), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Des Moines, fly to Buffalo Niagara International Airport
best- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF)DSM - BUF
6h 55m$446–2,270Bus
cheapest- Take the bus from Ames to Des Moines
- Take the bus from Des Moines to Chicago Bus Station
- Take the bus from Chicago Bus Station to Cleveland Bus Station
- Take the bus from Cleveland, OH to Buffalo, NY
21h 10m$106–286Bus, train via Des Moines
- Take the bus from Ames to Des Moines
- Take the bus from Des Moines to Chicago
- Take the train from Chicago Union Station to Buffalo Depew Station
20h 55m$144–492Drive 849.6 mi
- Drive from Ames to Buffalo849.6 mi
14h 57m$156–224Taxi to Fort Dodge Municipal Airport, fly to Buffalo Niagara International Airport
- Take the taxi from Ames to Fort Dodge Municipal Airport (FOD)
- Fly from Fort Dodge Municipal Airport (FOD) to Buffalo Niagara International Airport (BUF)FOD - BUF
7h 34m$369–1,451Shuttle to Des Moines, fly to Rochester, bus
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Rochester (ROC)DSM - ROC
- Take the bus from Rochester, NY to Buffalo, NY
9h 2m$296–1,425Bus, train
- Take the bus from Ames to Des Moines
- Take the bus from Des Moines to Chicago Bus Station
- Take the train from Chicago Union Station to Buffalo Depew Station
22h 3m$117–355Bus, train via Saint Paul
- Take the bus from Ames to St. Paul
- Take the train from St. Paul-Minneapolis to Chicago Union Station
- Take the train from Chicago Union Station to Buffalo Depew Station
25h 13m$155–601
Ames to Buffalo by bus
Questions & Answers
The cheapest way to get from Ames to Buffalo is to drive which costs $150 - $230 and takes 14h 57m.
The fastest way to get from Ames to Buffalo is to shuttle and fly which takes 6h 55m and costs $440 - $2,300.
No, there is no direct bus from Ames to Buffalo. However, there are services departing from Ames and arriving at Buffalo, NY via Des Moines, Chicago Bus Station and Cleveland, OH. The journey, including transfers, takes approximately 21h 10m.
The distance between Ames and Buffalo is 824 miles. The road distance is 854.6 miles.
The best way to get from Ames to Buffalo without a car is to bus and train via Des Moines which takes 20h 55m and costs $140 - $500.
It takes approximately 6h 55m to get from Ames to Buffalo, including transfers.
Ames to Buffalo bus services, operated by Jefferson Lines, depart from Ames station.
Ames to Buffalo bus services, operated by Jefferson Lines, arrive at Des Moines station.
Buffalo is 1h ahead of Ames. It is currently 11:36 AM in Ames and 12:36 PM in Buffalo.
Yes, the driving distance between Ames to Buffalo is 855 miles. It takes approximately 14h 57m to drive from Ames to Buffalo.
What companies run services between Ames, IA, USA and Buffalo, NY, USA?
You can take a bus from Ames to Buffalo, NY via Des Moines, Chicago Bus Station, Cleveland Bus Station, and Cleveland, OH in around 21h 10m.
- Website
- aa.com
Flights from Des Moines to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 5h 18m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $360–2,000
Flights from Des Moines to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $480–2,400
Flights from Des Moines to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $500–2,400
Flights from Des Moines to Rochester via Chicago O'Hare
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,100
Flights from Des Moines to Rochester via Philadelphia
- Ave. Duration
- 8h 19m
- When
- Every day
- Estimated price
- $250–1,200
- Website
- delta.com
Flights from Des Moines to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $360–2,000
Flights from Des Moines to Buffalo Niagara International Airport via Minneapolis
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $420–2,200
Flights from Des Moines to Rochester via Detroit
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $190–1,100
- Website
- united.com
Flights from Des Moines to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $360–2,000
Flights from Fort Dodge Municipal Airport to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 5h 14m
- When
- Tuesday to Sunday
- Estimated price
- $220–1,200
Flights from Des Moines to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $190–1,100
- Website
- southwest.com
Flights from Des Moines to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 5h 25m
- When
- Monday and Friday
- Estimated price
- $360–2,000
Flights from Des Moines to Rochester via Chicago Midway
- Ave. Duration
- 7h 20m
- When
- Monday and Friday
- Estimated price
- $190–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $55–210
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 24m
- Frequency
- 3 times a day
- Estimated price
- $70–220
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $3–45
- Book at
- https://www.jeffersonlines.com
Bus from Ames to St. Paul
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $20–100
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Chicago
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $65–143
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–100
- Flexible Fares
- $90–140
- Saver Fare
- $104
- Flex Fare
- $143
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–100
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Rochester, NY to Buffalo, NY
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 217+ hotels available in Buffalo.

















