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How to get fromAmerica to Sistine Chapelby train, plane, train (Eurostar, Trenitalia), bus, night train, car or car train

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There are 13 ways to get from America to Sistine Chapel by train, plane, train (Eurostar, Trenitalia), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Düsseldorf International Airport, fly to Fiumicino International Airport

    best
    1. Take the train from Venlo to Düsseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO)plane plane DUS - FCO
    7h 21m
    €108–276
  2. Train, train to Brussels Airport, fly to Fiumicino International Airport

    cheapest
    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Take the train from Eindhoven to Bredatrain train
    3. Take the train from Breda to Brussels Airport-Zaventemtrain train
    4. Fly from Brussels Airport (BRU) to Fiumicino International Airport (FCO)plane plane BRU - FCO
    8h 35m
    €96–259
  3. Train

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Take the train from Eindhoven to Rotterdam Centraaltrain train
    3. Take the train from Rotterdam Centraal to Chambery Challes Les Eauxtrain train
    4. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    5. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    16h 37m
    €333–713
  4. Train, bus

    1. Take the train from Venlo to Frankfurt(Main)Hbftrain train Ice
    2. Take the bus from Frankfurt to Pescarabus bus
    3. Take the bus from Pescara to Roma Termini Giolittibus bus
    24h 35m
    €161–295
  5. Train, night train

    1. Take the train from Venlo to Düsseldorf Hbftrain train
    2. Take the train from Düsseldorf Hbf to München Hbftrain train 41 / ...
    3. Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain night train Nj
    23h 3m
    €150–665
  6. Train to Amsterdam Airport Schiphol, fly to Fiumicino International Airport

    1. Take the train from Horst-Sevenum to Schiphol Airporttrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Fiumicino International Airport (FCO)plane plane AMS - FCO
    7h 19m
    €123–284
  7. Train to Eindhoven Airport, fly to Fiumicino International Airport

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Fly from Eindhoven Airport (EIN) to Fiumicino International Airport (FCO)plane plane EIN - FCO
    6h 19m
    €98–270
  8. Train, train to Cologne Bonn Airport, fly to Fiumicino International Airport

    1. Take the train from Venlo to Neuss Hbftrain train
    2. Take the train from Neuss Hbf to Koeln/Bonn Flughafentrain train
    3. Fly from Cologne Bonn Airport (CGN) to Fiumicino International Airport (FCO)plane plane CGN - FCO
    7h 46m
    €102–304
  9. Train, bus to Brussels South Charleroi Airport, fly to Roma Ciampino Airport

    1. Take the train from Roermond to Maastrichttrain train
    2. Take the bus from Maastricht Meerssenerweg 231 to Charleroi Airportbus bus
    3. Fly from Brussels South Charleroi Airport (CRL) to Roma Ciampino Airport (CIA)plane plane CRL - CIA
    9h 46m
    €102–314
  10. Train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport, train

    1. Take the train from Horst-Sevenum to Schiphol Airporttrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)plane plane AMS - FLR
    3. Take the train from Florence Santa Maria Novella to Roma Terminitrain train
    8h 48m
    €155–354
  11. Bus

    1. Take the bus from Venlo Station to Essen central train stationbus bus 023
    2. Take the bus from Essen central train station to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus bus 510 / ...
    27h 14m
    €113–250
  12. Drive 1,477.1 km

    1. Drive from America to Sistine Chapelcar car 1,477.1 km
    13h 47m
    €260–375
  13. Drive, car train

    1. Drive from America to Düsseldorf Hbfcar car
    2. Take the car train from Düsseldorf Hbf to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Sistine Chapelcar car
    14h 1m
    €223–1,199

Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO) flights

Calendar27Weekly Planes
Duration3h 41mAverage Duration
Ticket€74Cheapest Price
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Questions & Answers

What companies run services between America, Netherlands and Sistine Chapel, Vatican City?

You can take a vehicle from America to Sistine Chapel via Horst-Sevenum, Eindhoven, Rotterdam Centraal, Chambery Challes Les Eaux, Milano Centrale, Rome Termini, Termini, and Ottaviano in around 16h 37m. Alternatively, you can take a vehicle from America to Sistine Chapel via Sevenum, Berghemweg, Venlo Station, Essen central train station, Florence Villa Constanza Bus Station, Roma, Autostazione Tiburtina, and Emo in around 27h 14m.

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