Rome2Rio

How to get fromAmerica to Sienaby train, plane, train (Trenitalia), bus, car or car train

Find Transport to Siena

See all options

There are 13 ways to get from America to Siena by train, plane, train (Trenitalia), bus, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Düsseldorf International Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Venlo to Düsseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Florence Peretola Airport (FLR)plane plane DUS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 31m
    €122–309

  2. Bus

    cheapest
    1. Take the bus from Venlo Station to Essen central train stationbus bus 023
    2. Take the bus from Essen central train station to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    24h 11m
    €98–204

  3. Train

    1. Take the train from Venlo to Düsseldorf Hbftrain train
    2. Take the train from Düsseldorf Hbf to München Hbftrain train 41 / ...
    3. Take the train from München Hbf to Verona Porta Nuovatrain train 89
    4. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    18h 11m
    €214–583

  4. Drive 1,267.2 km

    1. Drive from America to Sienacar car 1,267.2 km
    12h 10m
    €225–325

  5. Train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport, train

    1. Take the train from Horst-Sevenum to Schiphol Airporttrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)plane plane AMS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 44m
    €137–317

  6. Train to Eindhoven Airport, fly to Pisa International Airport, train

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Fly from Eindhoven Airport (EIN) to Pisa International Airport (PSA)plane plane EIN - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 21m
    €100–320

  7. Train to Eindhoven Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Fly from Eindhoven Airport (EIN) to Bologna Guglielmo Marconi Airport (BLQ)plane plane EIN - BLQ
    3. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 10m
    €114–324

  8. Train to Amsterdam Airport Schiphol, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Horst-Sevenum to Schiphol Airporttrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane AMS - BLQ
    3. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 26m
    €146–329

  9. Train, train to Brussels Airport, fly to Florence Peretola Airport

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Take the train from Eindhoven to Bredatrain train
    3. Take the train from Breda to Brussels Airport-Zaventemtrain train
    4. Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane plane BRU - FLR
    5. Take the train from Firenze S.M.N. to Sienatrain train
    9h 50m
    €123–283

  10. Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Venlo to Düsseldorf Hbftrain train
    2. Take the train from Düsseldorf Hbf to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    5. Take the train from Firenze S.M.N. to Sienatrain train
    10h 6m
    €183–482

  11. Train, bus via Innsbruck

    1. Take the train from Venlo to Innsbruck Hauptbahnhoftrain train Drf
    2. Take the train from Innsbruck Hauptbahnhof to Bologna Centraletrain train 89
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train Fr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    20h 40m

  12. Train, bus

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Take the train from Eindhoven to Bredatrain train
    3. Take the train from Breda to Brussel-Noordtrain train
    4. Take the bus from Brussels-North Station to Bolognabus bus
    5. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    6. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    24h 40m

  13. Drive, car train

    1. Drive from America to Düsseldorf Hbfcar car
    2. Take the car train from Düsseldorf Hbf to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Sienacar car
    12h 23m
    €198–1,149

Düsseldorf International Airport (DUS) to Florence Peretola Airport (FLR) flights

Calendar35Weekly Planes
Duration3h 18mAverage Duration
Ticket€68Cheapest Price
See schedules

Questions & Answers

What companies run services between America, Netherlands and Siena, Italy?

You can take a vehicle from America to Siena via Horst-Sevenum, Venlo, Düsseldorf Hbf, München Hbf, Verona Porta Nuova, and Firenze S.M.N. in around 18h 11m. Alternatively, you can take a vehicle from America to Siena via Sevenum, Berghemweg, Venlo Station, Essen central train station, and Florence Villa Constanza Bus Station in around 24h 11m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Where to next?

Trips from America

Trips to Siena

Popular routes