There are 13 ways to get from America to Siena by train, plane, train (Trenitalia), bus, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Düsseldorf International Airport, fly to Florence Peretola Airport, train
best- Take the train from Venlo to Duesseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Florence Peretola Airport (FLR)plane DUS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 59m€142–311Fly Eindhoven Airport to Pisa International Airport, train
cheapest- Fly from Eindhoven Airport (EIN) to Pisa International Airport (PSA)plane EIN - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 3m€102–345Train
- Take the train from Venlo to Frankfurt(Main)Hbftrain Ice
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Centraletrain S11
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
17h 19m€341–579Train, bus
- Take the train from Venlo to Duesseldorf Hbftrain
- Take the bus from Düsseldorf central bus station to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
22h 29m€133–215Drive 1,267.5 km
- Drive from America to Sienacar 1,267.5 km
12h 10m€234–337Train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport, train
- Take the train from Horst-Sevenum to Schiphol Airport Train Stationtrain
- Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)plane AMS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 19m€151–317Fly Eindhoven Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Eindhoven Airport (EIN) to Bologna Guglielmo Marconi Airport (BLQ)plane EIN - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
7h 31m€115–367Train to Amsterdam Airport Schiphol, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Horst-Sevenum to Schiphol Airport Train Stationtrain
- Fly from Amsterdam Airport Schiphol (AMS) to Bologna Guglielmo Marconi Airport (BLQ)plane AMS - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 44m€148–347Train, train to Brussels Airport, fly to Florence Peretola Airport
- Take the train from Eindhoven Centraal to Bredatrain
- Take the train from Breda to Brussels Airport-Zaventemtrain
- Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane BRU - FLR
- Take the train from Firenze S.M.N. to Sienatrain
9h 3m€118–310Train to Frankfurt, fly to Florence Peretola Airport, train
- Take the train from Venlo to Frankfurt(M) Flughafen Fernbftrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
9h 14m€182–431Train to Amsterdam Airport Schiphol, fly to Pisa International Airport, train
- Take the train from Horst-Sevenum to Schiphol Airport Train Stationtrain
- Fly from Amsterdam Airport Schiphol (AMS) to Pisa International Airport (PSA)plane AMS - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
8h 16m€150–345Bus
- Take the bus from Venlo Station to Düsseldorf Airportbus
- Take the bus from Duesseldorf Worringer Straße to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
22h 49m€188–260Drive, car train
- Drive from America to Fuldacar
- Take the cartrain from Fulda to Villach Hbfcartrain
- Drive from Villach Hbf to Sienacar
18h 23m€244–342
Düsseldorf International Airport (DUS) to Florence Peretola Airport (FLR) flights
Comparing Your Travel Options
The cheapest way to get from America to Siena is to train and bus which costs €130 - €220 and takes 22h 29m.
The fastest way to get from America to Siena is to fly and train which takes 7h 3m and costs €100 - €350.
No, there is no direct bus from America to Siena. However, there are services departing from Sevenum, Berghemweg and arriving at Siena via Venlo Station, D-Flughafen Terminal S, Duesseldorf Worringer Straße and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 22h 49m.
No, there is no direct train from America to Siena. However, there are services departing from Horst-Sevenum and arriving at Siena via Venlo, Frankfurt, Chiasso, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 17h 19m.
The distance between America and Siena is 1078 km. The road distance is 1267.5 km.
The best way to get from America to Siena without a car is to train which takes 17h 19m and costs €340 - €600.
It takes approximately 7h 59m to get from America to Siena, including transfers.
America to Siena bus services, operated by FlixBus, depart from Venlo Station.
America to Siena train services, operated by Nederlandse Spoorwegen (NS), depart from Venlo station.
The best way to get from America to Siena is to train which takes 17h 19m and costs €340 - €600. Alternatively, you can bus, which costs €180 - €260 and takes 22h 49m.
What companies run services between America, Netherlands and Siena, Italy?
You can take a vehicle from America to Siena via Horst-Sevenum, Venlo, Frankfurt(Main)Hbf, Frankfurt, Chiasso, Milano Centrale, and Firenze S.M.N. in around 17h 19m. Alternatively, you can take a vehicle from America to Siena via Sevenum, Berghemweg, Venlo Station, Düsseldorf Airport, D-Flughafen Terminal S, Düsseldorf Hbf, Duesseldorf Worringer Straße, and Florence Villa Constanza Bus Station in around 22h 49m.
- Website
- lufthansa.com
Flights from Düsseldorf International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €180–650
Flights from Düsseldorf International Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €180–650
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- €110–800
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €110–370
Flights from Amsterdam Airport Schiphol to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €100–320
Flights from Amsterdam Airport Schiphol to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €180–650
Flights from Brussels Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €90–280
Flights from Brussels Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 25m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €200–280
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €160–600
- Website
- klm.com
Flights from Düsseldorf International Airport to Florence Peretola Airport via Amsterdam Airport Schiphol
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- €75–410
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- €80–440
Flights from Amsterdam Airport Schiphol to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- €65–380
Flights from Brussels Airport to Florence Peretola Airport via Amsterdam Airport Schiphol
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- €65–370
Flights from Amsterdam Airport Schiphol to Pisa International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Friday, and Sunday
- Estimated price
- €70–400
- Website
- swiss.com
Flights from Düsseldorf International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €90–250
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport via Zurich
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €110–290
Flights from Amsterdam Airport Schiphol to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 4h 15m
- When
- Tuesday to Thursday
- Estimated price
- €110–300
Flights from Brussels Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- €85–370
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €90–360
- Website
- ryanair.com
Flights from Eindhoven Airport to Pisa International Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Friday, and Sunday
- Estimated price
- €55–280
Flights from Eindhoven Airport to Pisa International Airport via London Stansted
- Ave. Duration
- 4h 10m
- When
- Friday
- Estimated price
- €55–280
Flights from Eindhoven Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- €65–290
Flights from Eindhoven Airport to Bologna Guglielmo Marconi Airport via London Stansted
- Ave. Duration
- 4h 10m
- When
- Tuesday
- Estimated price
- €65–290
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €160–550
- Website
- transavia.com
Flights from Eindhoven Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Sunday
- Estimated price
- €60–370
Flights from Amsterdam Airport Schiphol to Pisa International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Friday, and Sunday
- Estimated price
- €70–400
- Website
- eurowings.com
Flights from Düsseldorf International Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Tuesday, Thursday, and Sunday
- Estimated price
- €95–190
- Website
- vueling.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 55m
- When
- Thursday and Sunday
- Estimated price
- €50–200
- Website
- brusselsairlines.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €90–210
- Website
- condor.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €6–13
- Website
- Nederlandse Spoorwegen (NS)
Train from Venlo to Frankfurt(Main)Hbf
- Ave. Duration
- 2h 53m
- Frequency
- Hourly
- Estimated price
- €29–60
- Website
- Nederlandse Spoorwegen (NS)
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €6–13
- Website
- Nederlandse Spoorwegen (NS)
Train from Horst-Sevenum to Schiphol Airport Train Station
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €18–35
- Website
- Nederlandse Spoorwegen (NS)
Train from Horst-Sevenum to Schiphol Airport Train Station
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €18–35
- Website
- Nederlandse Spoorwegen (NS)
Train from Eindhoven Centraal to Breda
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–13
- Website
- Nederlandse Spoorwegen (NS)
Train from Breda to Brussels Airport-Zaventem
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €10–20
- Website
- Nederlandse Spoorwegen (NS)
Train from Venlo to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Horst-Sevenum to Schiphol Airport Train Station
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €18–35
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- 0180 6 9 27 37 27
- info@eurobahn.de
- Website
- Eurobahn
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- Eurobahn
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- Eurobahn
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €230–370
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Chiasso to Milano Centrale
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €19–30
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 58m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Breda to Brussels Airport-Zaventem
- Ave. Duration
- 1h 7m
- Frequency
- Hourly
- Estimated price
- €17–26
- Website
- Belgian Railways
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Venlo to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 21m
- Frequency
- Every 4 hours
- Estimated price
- €40–95
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- Urlaubs-Express (UEX)
Car train from Fulda to Villach Hbf
- Ave. Duration
- 9h 1m
- Frequency
- Once a week
- Estimated price
- €95–120
- Website
- Urlaubs-Express (UEX)
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Düsseldorf central bus station to Florence Villa Constanza Bus Station
- Ave. Duration
- 18h
- Frequency
- 4 times a week
- Estimated price
- €100–160
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Venlo Station to Düsseldorf Airport
- Ave. Duration
- 50 min
- Frequency
- 6 times a week
- Estimated price
- €5–8
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Duesseldorf Worringer Straße to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 58m
- Frequency
- Once a week
- Estimated price
- €150–210
- Website
- Onebus
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Booking & Getting There
America to Siena bus services, operated by FlixBus, arrive at Düsseldorf Airport station.
America to Siena train services, operated by Nederlandse Spoorwegen (NS), arrive at Frankfurt(Main)Hbf station.
Yes, the driving distance between America to Siena is 1267 km. It takes approximately 12h 10m to drive from America to Siena.
There are 2373+ hotels available in Siena.









































