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How to get fromAmarillo to Chicagoby plane, bus, train, car or bus (Greyhound, Flixbus)

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There are 7 ways to get from Amarillo to Chicago by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport

    best
    1. Fly from Rick Husband Amarillo International Airport (AMA) to Chicago Midway International Airport (MDW)plane plane AMA - MDW
    5h 32m
    $125–582

  2. Fly to Chicago O'Hare International Airport

    cheapest
    1. Fly from Rick Husband Amarillo International Airport (AMA) to Chicago O'Hare International Airport (ORD)plane plane AMA - ORD
    5h 32m
    $95–392

  3. Bus, train

    1. Take the bus from Amarillo Multimodal Transfer Sta to St Louis Bus Stationbus bus Greyhound US1210
    2. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    20h 25m
    $113–439

  4. Drive 1,042.5 mi

    1. Drive from Amarillo to Chicagocar car 1,042.5 mi
    16h 59m
    $191–275

  5. Fly to General Mitchell International Airport, train

    1. Fly from Rick Husband Amarillo International Airport (AMA) to General Mitchell International Airport (MKE)plane plane AMA - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    7h 42m
    $227–1,097

  6. Fly to South Bend, train

    1. Fly from Rick Husband Amarillo International Airport (AMA) to South Bend (SBN)plane plane AMA - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    8h 13m
    $156–692

  7. Bus

    1. Take the bus from Amarillo Multimodal Transfer Sta to St Louis Bus Stationbus bus Greyhound US1210
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    21h 45m
    $108–224

Amarillo to Chicago by bus and train

Calendar14Weekly Services
Duration20h 25mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

What companies run services between Amarillo, TX, USA and Chicago, IL, USA?

Southwest Airlines, American Airlines, and Frontier Airlines fly from Rick Husband Amarillo International Airport (AMA) to Chicago Midway International Airport (MDW) twice daily. Alternatively, you can take a bus from Amarillo Multimodal Transfer Sta to Chicago Bus Station via St Louis Bus Station in around 21h 45m.

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