Peter Pan Bus Lines operates a bus from Albany to Boston 4 times a day. Tickets cost $19 - $40 and the journey takes 3 h 25 min. Alternatively, Amtrak operates a train from Albany to Boston once daily, and the journey takes 4 h 56 min.
From Albany, NY bus to Boston, MA South Station. 3 h 25 min $40. From Albany-Rensselaer Amtrak train to Boston South Station Amtrak. 4 h 56 min. From Albany drive to Boston. 2 h 57 min $20. From Washington Ave & Hawk St - Capitol/Hawk Station line 737 bus to Albany airport, fly to Boston airport, then bus to Boston. 2 h 59 min $214.