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How to get fromAlachua to Chicagoby plane, bus (Flixbus, Greyhound), car, train, bus or bus (Greyhound)

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There are 8 ways to get from Alachua to Chicago by plane, bus (Flixbus, Greyhound), car, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Chicago Midway International Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Chicago Midway International Airport (MDW)plane plane GNV - MDW
    5h 46m
    $165–541

  2. Fly Gainesville Regional Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Chicago O'Hare International Airport (ORD)plane plane GNV - ORD
    5h 41m
    $140–431

  3. Bus

    1. Take the bus from Gainesville to Atlanta - Civic Center MARTA Stationbus bus Orlando
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus FlixBus 2512 / ...
    21h 19m
    $164–418

  4. Drive, train (Amtrak)

    1. Drive from Alachua to Jacksonvillecar car
    2. Take the train from Jacksonville to Chicago Union Stationtrain train Floridian
    36h 49m
    $243–1,319

  5. Drive 987.3 mi

    1. Drive from Alachua to Chicagocar car 987.3 mi
    17h 31m
    $181–261

  6. Bus to Jacksonville, fly to Chicago Midway International Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Chicago Midway International Airport (MDW)plane plane JAX - MDW
    7h 29m
    $184–694

  7. Bus to Jacksonville, fly to Chicago O'Hare International Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Chicago O'Hare International Airport (ORD)plane plane JAX - ORD
    7h 56m
    $159–524

  8. Bus via Gainesville Bus Stop (Greyhound)

    1. Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus bus Greyhound US0630
    2. Take the bus from Atlanta Bus Station to Chicago Train Stationbus bus Greyhound US0100
    24h 34m
    $178–385

Gainesville Regional Airport (GNV) to Chicago Midway International Airport (MDW) flights

Calendar34Weekly Planes
Duration6h 38mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

What companies run services between Alachua, FL, USA and Chicago, IL, USA?

Delta, American Airlines, and Southwest Airlines fly from Gainesville Regional Airport (GNV) to Chicago Midway International Airport (MDW) 5 times a day. Alternatively, you can take a vehicle from Alachua to Chicago Bus Station via Gainesville, Atlanta - Civic Center MARTA Station, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 21h 19m.

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Need to know: Greyhound

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