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How to get fromAgrigento to Sienaby train, plane, car, ferry, or bus

Find Transport to Siena

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There are 9 ways to get from Agrigento to Siena by train, plane, car, ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Palermo Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane plane PMO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 29m
    €94–225
  2. Bus via Florence

    cheapest
    1. Take the bus from Porto Empedocle Bus Station to Florence Villa Constanza Bus Stationbus bus Autoservizi Salemi 700
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    19h 11m
    €54–75
  3. Drive, ferry

    1. Drive from Agrigento to Palermocar car
    2. Take the ferry from Palermo to Civitavecchiaferry ferry
    3. Drive from Civitavecchia to Sienacar car
    18h 14m
    €94–159
  4. Bus

    1. Take the bus from Agrigento to Sienabus bus N528
    18h 45m
    €90–160
  5. Train to Palermo Airport, fly to Pisa International Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 12m
    €66–224
  6. Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane plane CTA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 47m
    €65–202
  7. Bus to Trapani Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Trapani Birgi Airportbus bus
    2. Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)plane plane TPS - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 25m
    €62–212
  8. Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane plane CTA - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 35m
    €64–181
  9. Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane plane PMO - PEG
    3. Take the bus from Perugia to Sienabus bus
    9h 11m
    €76–242

Agrigento to Siena by bus

Calendar7Weekly Buses
Duration18h 45mAverage Duration
Ticket€90Cheapest Price
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Questions & Answers

What companies run services between Agrigento, Italy and Siena, Italy?

FlixBus operates a bus from Agrigento to Siena once daily. Tickets cost €90–160 and the journey takes 18h 45m.

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Ferry operators

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