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How to get fromAgrigento to Sienaby train, plane, train (Trenitalia), bus, car or ferry

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There are 10 ways to get from Agrigento to Siena by train, plane, train (Trenitalia), bus, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Palermo Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain
    2. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)planePMO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 47m
    €75–218
  2. Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train

    cheapest
    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)planeCTA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 58m
    €53–197
  3. Train

    1. Take the train from Agrigento Centrale to Termini ImeresetrainRe
    2. Take the train from Termini Imerese to Roma TerminitrainIc
    3. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    4. Take the train from Firenze S.M.N. to SienatrainRe
    18h 3m
    €106–180
  4. Bus

    1. Take the bus from Agrigento to SienabusN528
    18h 45m
    €70–100
  5. Drive, ferry

    1. Drive from Agrigento to Messina Marittimacar
    2. Take the ferry from Messina Marittima to Villa San Giovanniferry
    3. Drive from Villa San Giovanni to Sienacar
    11h 32m
    €170–259
  6. Train to Palermo Airport, fly to Pisa International Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain
    2. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)planePMO - PSA
    3. Take the train from Pisa Centrale to Empolitrain
    4. Take the train from Empoli to Sienatrain
    7h 34m
    €90–236
  7. Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)planeCTA - PSA
    3. Take the train from Pisa Centrale to Empolitrain
    4. Take the train from Empoli to Sienatrain
    7h 50m
    €73–215
  8. Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain
    2. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)planePMO - PEG
    3. Take the bus from Perugia to Sienabus
    7h 33m
    €106–392
  9. Bus to Trapani Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Trapani Birgi Airportbus
    2. Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)planeTPS - PSA
    3. Take the train from Pisa Centrale to Empolitrain
    4. Take the train from Empoli to Sienatrain
    7h 45m
    €89–302
  10. Bus via Florence

    1. Take the bus from Porto Empedocle Bus Station to Florence Villa Constanza Bus StationbusAutoservizi Salemi 700
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131R / ...
    19h 4m

Agrigento to Siena by train

Calendar7Weekly Trains
Duration18h 3mAverage Duration
Ticket€106Cheapest Price
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Questions & Answers

What companies run services between Agrigento, Italy and Siena, Italy?

You can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 18h 3m. Alternatively, FlixBus operates a bus from Agrigento to Siena once daily. Tickets cost €70–100 and the journey takes 18h 45m.

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