There are 11 ways to get from Agrigento to Siena by train, plane, bus, train (Trenitalia), car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Palermo Airport, fly to Florence Peretola Airport, train
best- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane PMO - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 47m€94–205Bus via Rome
cheapest- Take the bus from Agrigento Piazzale Vittorio Emanuele to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Siena - p.zza Rossellibus Lamezia Terme
17h 50m€49–69Train (Trenitalia)
- Take the train from Agrigento Centrale to Termini Imeresetrain Re
- Take the train from Termini Imerese to Roma Terminitrain Ic
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
18h 3m€134–304Drive, ferry
- Drive from Agrigento to Palermocar
- Take the ferry from Palermo to Civitavecchiaferry
- Drive from Civitavecchia to Sienacar
18h 16m€92–158Train to Palermo Airport, fly to Pisa International Airport, train
- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane PMO - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 35m€66–224Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 3m€54–180Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 56m€68–209Bus to Trapani Airport, fly to Pisa International Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Trapani Birgi Airportbus
- Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)plane TPS - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 46m€67–372Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus
- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane PMO - PEG
- Take the bus from Perugia to Sienabus
9h 13m€65–281Bus
- Take the bus from Agrigento to Sienabus N528
18h 45m€80–140Train via Chiusi (Trenitalia)
- Take the train from Agrigento Centrale to Termini Imeresetrain Re
- Take the train from Termini Imerese to Roma Terminitrain Ic
- Take the train from Roma Termini to Chiusi-Chianciano T.train
- Take the train from Chiusi-Chianciano T. to Sienatrain Re
19h 3m€123–263
Agrigento to Siena by bus
Questions & Answers
The cheapest way to get from Agrigento to Siena is to bus via Rome which costs €45 - €70 and takes 17h 50m.
The fastest way to get from Agrigento to Siena is to train and fly which takes 7h 35m and costs €65 - €230.
Yes, there is a direct bus departing from Agrigento and arriving at Siena. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
No, there is no direct train from Agrigento to Siena. However, there are services departing from Agrigento Centrale and arriving at Siena via Termini Imerese, Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 18h 3m.
The distance between Agrigento and Siena is 912 km.
The best way to get from Agrigento to Siena without a car is to bus via Rome which takes 17h 50m and costs €45 - €70.
It takes approximately 7h 47m to get from Agrigento to Siena, including transfers.
Agrigento to Siena bus services, operated by Autoservizi Salemi Srl, depart from Agrigento Piazzale Vittorio Emanuele station.
Agrigento to Siena train services, operated by Trenitalia, depart from Agrigento Centrale station.
The best way to get from Agrigento to Siena is to bus via Rome which takes 17h 50m and costs €45 - €70. Alternatively, you can train, which costs €130 - €310 and takes 18h 3m.
What companies run services between Agrigento, Italy and Siena, Italy?
You can take a bus from Agrigento Piazzale Vittorio Emanuele to Siena - p.zza Rosselli via Roma, Autostazione Tiburtina in around 17h 50m. Alternatively, you can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 18h 3m.
- Website
- ryanair.com
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €28–150
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €40–160
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 25m
- When
- Tuesday
- Estimated price
- €40–160
Flights from Trapani Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €40–330
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–190
- Website
- ita-airways.com
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- €70–150
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- €70–130
- Website
- volotea.com
Flights from Palermo Airport to Florence Peretola Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €40–130
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €27–150
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €70–130
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €29–130
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Agrigento Centrale to Palermo Aeroporto
- Ave. Duration
- 2h 39m
- Frequency
- Twice daily
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Agrigento Centrale to Termini Imerese
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a day
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €18–35
- Website
- https://www.trenitalia.com/en.html
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- €11–18
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Termini Imerese to Roma Termini
- Ave. Duration
- 11h 9m
- Frequency
- Once daily
- Estimated price
- €85–190
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- €26–60
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 48m
- Frequency
- 3 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Agrigento Piazzale Vittorio Emanuele to Roma, Autostazione Tiburtina
- Ave. Duration
- 13h 50m
- Frequency
- Once daily
- Estimated price
- €35–55
- Schedules at
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Siena - p.zza Rosselli
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- €10–15
- Schedules at
- autolineefederico.it
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–15
- Website
- https://saistrasporti.it/en-US
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 39m
- Frequency
- Twice daily
- Estimated price
- €11–19
- Website
- https://www.flixbus.co.uk
Bus from Perugia to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €7–13
- Website
- https://www.flixbus.co.uk
Bus from Agrigento to Siena
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0922.20414
- info@autolineelumia.it
- Website
- autolineelumia.com
Bus from Agrigento Piazzale Rosselli to Trapani Birgi Airport
- Ave. Duration
- 2h 50m
- Frequency
- 5 times a day
- Estimated price
- €10–13
- Schedules at
- autolineelumia.com
- .
- €10–13
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Ferry from Palermo to Civitavecchia
- Ave. Duration
- 13h 45m
- Frequency
- 3 times a week
- Estimated price
- €45–85
- Website
- https://www.gnv.it/en
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More Questions & Answers
Agrigento to Siena bus services, operated by Autoservizi Salemi Srl, arrive at Roma, Autostazione Tiburtina station.
Agrigento to Siena train services, operated by Trenitalia, arrive at Termini Imerese station.
Book your Agrigento to Siena train tickets online with Omio.
Book your Agrigento to Siena bus tickets online with Omio.
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