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How to get fromAgrigento to Sienaby train, plane, train (Trenitalia), bus, car or ferry

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There are 9 ways to get from Agrigento to Siena by train, plane, train (Trenitalia), bus, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Palermo Airport, fly to Pisa International Airport, train

    best
    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 34m
    €91–246
  2. Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train

    cheapest
    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane plane CTA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 58m
    €51–188
  3. Train

    1. Take the train from Agrigento Centrale to Termini Imeresetrain train Re
    2. Take the train from Termini Imerese to Roma Terminitrain train Ic
    3. Take the train from Roma Termini to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    18h 3m
    €118–181
  4. Bus

    1. Take the bus from Agrigento to Sienabus bus N528
    18h 45m
    €85–130
  5. Drive, ferry

    1. Drive from Agrigento to Messina Marittimacar car
    2. Take the ferry from Messina Marittima to Villa San Giovanniferry ferry
    3. Drive from Villa San Giovanni to Sienacar car
    11h 37m
    €171–269
  6. Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane plane CTA - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 50m
    €73–225
  7. Train to Palermo Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane PMO - BLQ
    3. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 44m
    €88–281
  8. Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane plane PMO - PEG
    3. Take the bus from Perugia to Sienabus bus
    7h 33m
    €87–388
  9. Bus via Florence

    1. Take the bus from Porto Empedocle Bus Station to Florence Villa Constanza Bus Stationbus bus Autoservizi Salemi 700
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    19h 4m

Agrigento to Siena by train

Calendar7Weekly Trains
Duration18h 3mAverage Duration
Ticket€118Cheapest Price
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Questions & Answers

What companies run services between Agrigento, Italy and Siena, Italy?

You can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 18h 3m. Alternatively, FlixBus operates a bus from Agrigento to Siena once daily. Tickets cost €85–130 and the journey takes 18h 45m.

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