There are 9 ways to get from Agrigento to Siena by train, plane, car, ferry, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Palermo Airport, fly to Florence Peretola Airport, train
best- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane PMO - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 29m€94–225Bus via Florence
cheapest- Take the bus from Porto Empedocle Bus Station to Florence Villa Constanza Bus Stationbus Autoservizi Salemi 700
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
19h 11m€54–75Drive, ferry
- Drive from Agrigento to Palermocar
- Take the ferry from Palermo to Civitavecchiaferry
- Drive from Civitavecchia to Sienacar
18h 14m€94–159Bus
- Take the bus from Agrigento to Sienabus N528
18h 45m€90–160Train to Palermo Airport, fly to Pisa International Airport, train
- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane PMO - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 12m€66–224Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 47m€65–202Bus to Trapani Airport, fly to Pisa International Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Trapani Birgi Airportbus
- Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)plane TPS - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 25m€62–212Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 35m€64–181Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus
- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane PMO - PEG
- Take the bus from Perugia to Sienabus
9h 11m€76–242
Agrigento to Siena by bus
Questions & Answers
The cheapest way to get from Agrigento to Siena is to bus via Florence which costs €50 - €75 and takes 19h 11m.
The fastest way to get from Agrigento to Siena is to train and fly which takes 7h 12m and costs €65 - €230.
Yes, there is a direct bus departing from Agrigento and arriving at Siena. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
The distance between Agrigento and Siena is 912 km.
The best way to get from Agrigento to Siena without a car is to bus which takes 18h 45m and costs €90 - €160.
It takes approximately 7h 29m to get from Agrigento to Siena, including transfers.
Agrigento to Siena bus services, operated by FlixBus, depart from Agrigento station.
Agrigento to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Agrigento to Siena bus tickets online with Omio and FlixBus.
There are 2517+ hotels available in Siena.
What companies run services between Agrigento, Italy and Siena, Italy?
FlixBus operates a bus from Agrigento to Siena once daily. Tickets cost €90–160 and the journey takes 18h 45m.
- Website
- ryanair.com
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €28–160
Flights from Trapani Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–170
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–130
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €45–180
- Website
- ita-airways.com
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- €80–160
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- €80–160
- Website
- volotea.com
Flights from Palermo Airport to Florence Peretola Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €40–140
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €80–160
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €27–140
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Friday, and Sunday
- Estimated price
- €55–180
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Agrigento Centrale to Palermo Aeroporto
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Agrigento Centrale to Palermo Aeroporto
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Agrigento Centrale to Palermo Aeroporto
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Agrigento to Siena
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €90–160
- Website
- https://www.flixbus.co.uk
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 39m
- Frequency
- Twice daily
- Estimated price
- €13–22
- Website
- https://www.flixbus.co.uk
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 39m
- Frequency
- Twice daily
- Estimated price
- €13–22
- Website
- https://www.flixbus.co.uk
Bus from Perugia to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €8–14
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–15
- Website
- https://saistrasporti.it/en-US
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–15
- Website
- https://saistrasporti.it/en-US
- Phone
- +39 0922.20414
- info@autolineelumia.it
- Website
- autolineelumia.com
Bus from Agrigento Piazzale Rosselli to Trapani Birgi Airport
- Ave. Duration
- 2h 50m
- Frequency
- 5 times a day
- Estimated price
- €10–13
- Schedules at
- autolineelumia.com
- .
- €10–13
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Porto Empedocle Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h
- Frequency
- Once a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Ferry from Palermo to Civitavecchia
- Ave. Duration
- 13h 45m
- Frequency
- 3 times a week
- Estimated price
- €45–85
- Website
- https://www.gnv.it/en
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