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How to get fromAgrigento to Sienaby train, plane, train (Trenitalia), car, ferry, or bus

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There are 10 ways to get from Agrigento to Siena by train, plane, train (Trenitalia), car, ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Palermo Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane plane PMO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 45m
    €89–235

  2. Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train

    cheapest
    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane plane CTA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 3m
    €55–211

  3. Train (Trenitalia)

    1. Take the train from Agrigento Centrale to Termini Imeresetrain train Re
    2. Take the train from Termini Imerese to Roma Terminitrain train Ic
    3. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    17h 44m
    €135–304

  4. Drive, ferry

    1. Drive from Agrigento to Palermocar car
    2. Take the ferry from Palermo to Civitavecchiaferry ferry
    3. Drive from Civitavecchia to Sienacar car
    18h 14m
    €92–163

  5. Bus

    1. Take the bus from Agrigento to Sienabus bus N528
    18h 45m
    €90–150

  6. Train to Palermo Airport, fly to Pisa International Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 33m
    €73–284

  7. Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane plane CTA - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 56m
    €69–220

  8. Bus to Trapani Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Trapani Birgi Airportbus bus
    2. Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)plane plane TPS - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 46m
    €62–332

  9. Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain train
    2. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane plane PMO - PEG
    3. Take the bus from Perugia to Sienabus bus
    9h 11m
    €81–271

  10. Bus via Florence

    1. Take the bus from Agrigento Piazzale Rosselli to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    22h 36m

Agrigento to Siena by train (Trenitalia)

Calendar14Weekly Trains
Duration17h 44mAverage Duration
Ticket€135Cheapest Price
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Questions & Answers

Map of how to get from Agrigento to Siena.ExpandLaunch map view
  • Distance: 911.7 km
  • Duration: 7h 45m

What companies run services between Agrigento, Italy and Siena, Italy?

You can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 17h 44m. Alternatively, FlixBus operates a bus from Agrigento to Siena once daily. Tickets cost €90–150 and the journey takes 18h 45m.

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