There are 11 ways to get from Agrigento to Siena by train, plane, train (Trenitalia), bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Palermo Airport, fly to Florence Peretola Airport, train
best- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane PMO - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 47m€69–199Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
cheapest- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 58m€51–158Train
- Take the train from Agrigento Centrale to Termini Imeresetrain Re
- Take the train from Termini Imerese to Roma Terminitrain Ic
- Take the train from Roma Termini to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain Re
18h 19m€83–171Bus
- Take the bus from Agrigento to Sienabus N528
18h 45m€85–130Drive, ferry
- Drive from Agrigento to Messina Marittimacar
- Take the ferry from Messina Marittima to Villa San Giovanniferry
- Drive from Villa San Giovanni to Sienacar
11h 37m€170–258Train to Palermo Airport, fly to Pisa International Airport, train
- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane PMO - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 34m€76–226Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 50m€68–205Train to Palermo Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane PMO - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
8h 43m€82–271Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus
- Take the train from Agrigento Centrale to Palermo Aeroportotrain
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane PMO - PEG
- Take the bus from Perugia to Sienabus
9h 3m€54–280Bus via Florence
- Take the bus from Porto Empedocle Bus Station to Florence Villa Constanza Bus Stationbus Autoservizi Salemi 700
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
19h 4mTrain via Chiusi (Trenitalia)
- Take the train from Agrigento Centrale to Palermo Centraletrain Re
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Chiusi-Chianciano T.train
- Take the train from Chiusi-Chianciano T. to Sienatrain Re
19h 57m€57–152
Agrigento to Siena by train
Questions & Answers
The cheapest way to get from Agrigento to Siena is to bus and fly and train which costs €50 - €160 and takes 7h 58m.
The fastest way to get from Agrigento to Siena is to train and fly which takes 7h 34m and costs €75 - €230.
Yes, there is a direct bus departing from Agrigento and arriving at Siena. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
No, there is no direct train from Agrigento to Siena. However, there are services departing from Agrigento Centrale and arriving at Siena via Termini Imerese, Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 18h 19m.
The distance between Agrigento and Siena is 912 km.
The best way to get from Agrigento to Siena without a car is to train which takes 18h 19m and costs €80 - €180.
It takes approximately 7h 47m to get from Agrigento to Siena, including transfers.
Agrigento to Siena bus services, operated by FlixBus, depart from Agrigento station.
Agrigento to Siena train services, operated by Trenitalia, depart from Agrigento Centrale station.
The best way to get from Agrigento to Siena is to train which takes 18h 19m and costs €80 - €180. Alternatively, you can bus, which costs €85 - €130 and takes 18h 45m.
What companies run services between Agrigento, Italy and Siena, Italy?
You can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 18h 19m. Alternatively, FlixBus operates a bus from Agrigento to Siena once daily. Tickets cost €85–130 and the journey takes 18h 45m.
- Website
- ryanair.com
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €40–190
Flights from Palermo Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- €40–190
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–160
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Malta
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €35–160
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €35–200
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €30–230
- Website
- ita-airways.com
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €65–160
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €70–120
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €45–160
- Website
- volotea.com
Flights from Palermo Airport to Florence Peretola Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €29–130
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €26–120
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €28–170
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Agrigento Centrale to Palermo Aeroporto
- Ave. Duration
- 2h 39m
- Frequency
- Twice daily
- Estimated price
- €10–16
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Agrigento Centrale to Termini Imerese
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
Train from Agrigento Centrale to Palermo Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 2 hours
- Estimated price
- €12
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €12–13
- Website
- https://www.trenitalia.com/en.html
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- €10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Termini Imerese to Roma Termini
- Ave. Duration
- 11h 9m
- Frequency
- Once daily
- Estimated price
- €40–100
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 34m
- Frequency
- Once daily
- Estimated price
- €27–110
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 48m
- Frequency
- 3 times a day
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Florence Santa Maria Novella
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €22–50
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Agrigento to Siena
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €85–130
- Website
- https://www.flixbus.co.uk
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 39m
- Frequency
- Twice daily
- Estimated price
- €8–11
- Website
- https://www.flixbus.co.uk
Bus from Perugia to Siena
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–15
- Website
- https://saistrasporti.it/en-US
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Porto Empedocle Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h
- Frequency
- Once a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
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More Questions & Answers
Agrigento to Siena bus services, operated by FlixBus, arrive at Siena station.
Agrigento to Siena train services, operated by Trenitalia, arrive at Termini Imerese station.
Book your Agrigento to Siena train tickets online with Omio.
Book your Agrigento to Siena bus tickets online with Omio and FlixBus.
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