There are 11 ways to get from Agrigento to Siena by train, plane, train (Trenitalia), bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Palermo Airport, fly to Florence Peretola Airport, train
best- Take the train from Agrigento Centrale to Palermo Aeroporto
- Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)PMO - FLR
- Take the train from Firenze S.M.N. to Siena
7h 51m€78–271Bus via Rome
cheapest- Take the bus from Porto Empedocle Bus Station to Roma, Autostazione TiburtinaAutoservizi Salemi 701
- Take the bus from Roma, Autostazione Tiburtina to Siena - p.zza RosselliLamezia Terme
18h 15m€40–57Train
- Take the train from Agrigento Centrale to Termini ImereseRe
- Take the train from Termini Imerese to Roma TerminiIc
- Take the train from Roma Termini to Florence Santa Maria Novella
- Take the train from Firenze S.M.N. to SienaRe
18h 2m€90–201Drive, ferry
- Drive from Agrigento to Messina Marittima
- Take the ferry from Messina Marittima to Villa San Giovanni
- Drive from Villa San Giovanni to Siena
11h 32m€181–269Train to Palermo Airport, fly to Pisa International Airport, train
- Take the train from Agrigento Centrale to Palermo Aeroporto
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)PMO - PSA
- Take the train from Pisa Centrale to Empoli
- Take the train from Empoli to Siena
7h 35m€74–317Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)CTA - FLR
- Take the train from Firenze S.M.N. to Siena
8h 5m€52–225Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)CTA - PSA
- Take the train from Pisa Centrale to Empoli
- Take the train from Empoli to Siena
7h 54m€73–251Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus
- Take the train from Agrigento Centrale to Palermo Aeroporto
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)PMO - PEG
- Take the bus from Perugia to Siena
7h 30m€115–482Train to Palermo Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Agrigento Centrale to Palermo Aeroporto
- Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)PMO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Siena
8h 35m€69–298Bus
- Take the bus from Agrigento to SienaN528
18h 45m€70–100Train via Chiusi
- Take the train from Agrigento Centrale to Termini ImereseRe
- Take the train from Termini Imerese to Roma TerminiIc
- Take the train from Roma Termini to Chiusi-Chianciano T.Re
- Take the train from Chiusi-Chianciano T. to SienaRe
18h 54m€77–163
Agrigento to Siena by train
Questions & Answers
The cheapest way to get from Agrigento to Siena is to bus via Rome which costs €40 - €60 and takes 18h 15m.
The fastest way to get from Agrigento to Siena is to train and fly and bus which takes 7h 30m and costs €110 - €490.
Yes, there is a direct bus departing from Agrigento and arriving at Siena. Services depart once daily, and operate every day. The journey takes approximately 18h 45m.
No, there is no direct train from Agrigento to Siena. However, there are services departing from Agrigento Centrale and arriving at Siena via Termini Imerese, Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 18h 2m.
The distance between Agrigento and Siena is 912 km.
The best way to get from Agrigento to Siena without a car is to train which takes 18h 2m and costs €90 - €210.
It takes approximately 7h 51m to get from Agrigento to Siena, including transfers.
Agrigento to Siena bus services, operated by Autoservizi Salemi Srl, depart from Porto Empedocle Bus Station.
Agrigento to Siena train services, operated by Trenitalia S.p.A., depart from Agrigento Centrale station.
The best way to get from Agrigento to Siena is to train which takes 18h 2m and costs €90 - €210. Alternatively, you can bus via Rome, which costs €40 - €60 and takes 18h 15m.
What companies run services between Agrigento, Italy and Siena, Italy?
You can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 18h 2m. Alternatively, you can take a bus from Porto Empedocle Bus Station to Siena - p.zza Rosselli via Roma, Autostazione Tiburtina in around 18h 15m.
- Website
- ryanair.com
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €50–230
Flights from Palermo Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- €50–230
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €45–170
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Malta
- Ave. Duration
- 3h 45m
- When
- Friday
- Estimated price
- €45–170
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €80–350
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €30–170
- Website
- ita-airways.com
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €65–170
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €70–160
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €45–160
- Website
- volotea.com
Flights from Palermo Airport to Florence Peretola Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €30–200
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €27–170
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–200
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Agrigento Centrale to Palermo Aeroporto
- Ave. Duration
- 2h 36m
- Frequency
- 3 times a day
- Estimated price
- €10–35
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €22–35
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €6–18
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €12–18
Train from Agrigento Centrale to Termini Imerese
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €7–19
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €13–19
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–9
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €6–9
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–12
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €8–12
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €6–17
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €12–17
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 44m
- Frequency
- 5 times a day
- Estimated price
- €9–28
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €20–28
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 31m
- Frequency
- Every 2 hours
- Estimated price
- €6–17
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €11–17
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Termini Imerese to Roma Termini
- Ave. Duration
- 11h 4m
- Frequency
- Once daily
- Estimated price
- €55–100
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–13
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- €11–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Florence Santa Maria Novella
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €22–65
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €15–40
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Schedules at
- trenitalia.com
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Porto Empedocle Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 14h 15m
- Frequency
- Once a week
- Estimated price
- €30–45
- Schedules at
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Siena - p.zza Rosselli
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- €10–15
- Schedules at
- autolineefederico.it
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €11–15
- Website
- https://saistrasporti.it/en-US
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossa
- Ave. Duration
- 2h 39m
- Frequency
- Once daily
- Estimated price
- €9–12
- Website
- https://www.flixbus.co.uk
Bus from Perugia to Siena
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €7–19
- Website
- https://www.flixbus.co.uk
Bus from Agrigento to Siena
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €70–100
- Website
- https://www.flixbus.co.uk
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
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More Questions & Answers
Agrigento to Siena bus services, operated by Autoservizi Salemi Srl, arrive at Roma, Autostazione Tiburtina station.
Agrigento to Siena train services, operated by Trenitalia S.p.A., arrive at Termini Imerese station.
Book your Agrigento to Siena train tickets online with Omio.
Book your Agrigento to Siena bus tickets online with Omio.
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