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How to get fromAgrigento to Sienaby train, plane, train (Trenitalia), bus, car or ferry

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There are 11 ways to get from Agrigento to Siena by train, plane, train (Trenitalia), bus, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Palermo Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain
    2. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)planePMO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 51m
    €78–271
  2. Bus via Rome

    cheapest
    1. Take the bus from Porto Empedocle Bus Station to Roma, Autostazione TiburtinabusAutoservizi Salemi 701
    2. Take the bus from Roma, Autostazione Tiburtina to Siena - p.zza RossellibusLamezia Terme
    18h 15m
    €40–57
  3. Train

    1. Take the train from Agrigento Centrale to Termini ImeresetrainRe
    2. Take the train from Termini Imerese to Roma TerminitrainIc
    3. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    4. Take the train from Firenze S.M.N. to SienatrainRe
    18h 2m
    €90–201
  4. Drive, ferry

    1. Drive from Agrigento to Messina Marittimacar
    2. Take the ferry from Messina Marittima to Villa San Giovanniferry
    3. Drive from Villa San Giovanni to Sienacar
    11h 32m
    €181–269
  5. Train to Palermo Airport, fly to Pisa International Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain
    2. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)planePMO - PSA
    3. Take the train from Pisa Centrale to Empolitrain
    4. Take the train from Empoli to Sienatrain
    7h 35m
    €74–317
  6. Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)planeCTA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    8h 5m
    €52–225
  7. Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train

    1. Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)planeCTA - PSA
    3. Take the train from Pisa Centrale to Empolitrain
    4. Take the train from Empoli to Sienatrain
    7h 54m
    €73–251
  8. Train to Palermo Airport, fly to Perugia Sant'Egidio Airport, bus

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain
    2. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)planePMO - PEG
    3. Take the bus from Perugia to Sienabus
    7h 30m
    €115–482
  9. Train to Palermo Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Agrigento Centrale to Palermo Aeroportotrain
    2. Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)planePMO - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train
    4. Take the train from Firenze S.M.N. to Sienatrain
    8h 35m
    €69–298
  10. Bus

    1. Take the bus from Agrigento to SienabusN528
    18h 45m
    €70–100
  11. Train via Chiusi

    1. Take the train from Agrigento Centrale to Termini ImeresetrainRe
    2. Take the train from Termini Imerese to Roma TerminitrainIc
    3. Take the train from Roma Termini to Chiusi-Chianciano T.trainRe
    4. Take the train from Chiusi-Chianciano T. to SienatrainRe
    18h 54m
    €77–163

Agrigento to Siena by train

Calendar7Weekly Trains
Duration18h 2mAverage Duration
Ticket€90Cheapest Price
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Questions & Answers

What companies run services between Agrigento, Italy and Siena, Italy?

You can take a train from Agrigento Centrale to Siena via Termini Imerese, Roma Termini, and Firenze S.M.N. in around 18h 2m. Alternatively, you can take a bus from Porto Empedocle Bus Station to Siena - p.zza Rosselli via Roma, Autostazione Tiburtina in around 18h 15m.

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