There are 11 ways to get from Agrigento to Isernia by train, ferry, bus, car, car ferry, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, ferry
best- Take the train from Agrigento Centrale to Termini Imeresetrain Re
- Take the train from Termini Imerese to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Iserniatrain Re
13h 18mBus via Caserta
cheapest- Take the bus from Agrigento Piazzale Vittorio Emanuele to Caserta pzza Garibaldibus
- Take the bus from Caserta Terminal Bus to Iserniabus 433
13h 39m€38–54Drive, car ferry
- Drive from Agrigento to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Iserniacar
8h 58m€148–232Train to Palermo Airport, fly to Naples Airport, train
- Take the train from Agrigento Bassa to Palermo Centraletrain
- Fly from Palermo Airport (PMO) to Naples Airport (NAP)plane PMO - NAP
- Take the train from Caserta to Iserniatrain
8h 51m€55–218Train (Trenitalia)
- Take the train from Agrigento Centrale to Termini Imeresetrain Re
- Take the train from Termini Imerese to Napoli Centraletrain Ic
- Take the train from Napoli Centrale to Iserniatrain Re
14h 11m€92–158Bus
- Take the bus from Agrigento Piazzale Rosselli to Casello - A1 Ingresso Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
18h 47m€179–243Bus to Catania–Fontanarossa Airport, fly to Naples Airport, train
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane CTA - NAP
- Take the train from Caserta to Iserniatrain
8h 36m€50–199Train to Palermo Airport, fly to Fiumicino International Airport, train
- Take the train from Agrigento Bassa to Palermo Centraletrain
- Fly from Palermo Airport (PMO) to Fiumicino International Airport (FCO)plane PMO - FCO
- Take the train from Roma Termini to Iserniatrain
9h 6m€63–190Train, train to Vincenzo Magliocco Airport, fly to Fiumicino International Airport
- Take the train from Agrigento Bassa to Canicatti'train
- Take the train from Canicatti' to Comisotrain
- Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)plane CIY - FCO
- Take the train from Roma Termini to Iserniatrain
9h 25m€92–354Bus to Catania–Fontanarossa Airport, fly to Abruzzo Airport, bus
- Take the bus from Agrigento Piazzale Rosselli to Aeroporto Fontanarossabus
- Fly from Catania–Fontanarossa Airport (CTA) to Abruzzo Airport (PSR)plane CTA - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
9h 40m€54–211Bus to Trapani Airport, fly to Abruzzo Airport, bus
- Take the bus from Agrigento Piazzale Rosselli to Trapani Birgi Airportbus
- Fly from Trapani Airport (TPS) to Abruzzo Airport (PSR)plane TPS - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
9h 35m€52–253
Palermo Airport (PMO) to Naples Airport (NAP) flights
Comparing Your Travel Options
The cheapest way to get from Agrigento to Isernia is to bus via Caserta which costs €35 - €55 and takes 13h 39m.
The fastest way to get from Agrigento to Isernia is to bus and fly and train which takes 8h 36m and costs €45 - €200.
No, there is no direct bus from Agrigento to Isernia. However, there are services departing from Agrigento Piazzale Vittorio Emanuele and arriving at Isernia via Caserta Terminal Bus. The journey, including transfers, takes approximately 13h 39m.
No, there is no direct train from Agrigento to Isernia. However, there are services departing from Agrigento Centrale and arriving at Isernia via Termini Imerese and Napoli Centrale. The journey, including transfers, takes approximately 14h 11m.
The distance between Agrigento and Isernia is 831 km.
The best way to get from Agrigento to Isernia without a car is to train and ferry which takes 13h 18m and costs .
It takes approximately 13h 18m to get from Agrigento to Isernia, including transfers.
Agrigento to Isernia bus services, operated by Autoservizi Salemi Srl, depart from Agrigento Piazzale Vittorio Emanuele station.
Agrigento to Isernia train services, operated by Trenitalia, depart from Agrigento Centrale station.
The best way to get from Agrigento to Isernia is to bus via Caserta which takes 13h 39m and costs €35 - €55. Alternatively, you can train, which costs €90 - €160 and takes 14h 11m.
What companies run services between Agrigento, Italy and Isernia, Italy?
You can take a bus from Agrigento Piazzale Vittorio Emanuele to Isernia via Caserta pzza Garibaldi and Caserta Terminal Bus in around 13h 39m. Alternatively, you can take a train from Agrigento Centrale to Isernia via Termini Imerese and Napoli Centrale in around 14h 11m.
- Website
- ryanair.com
Flights from Palermo Airport to Naples Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €27–220
Flights from Catania–Fontanarossa Airport to Naples Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €25–160
Flights from Palermo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €23–120
Flights from Catania–Fontanarossa Airport to Abruzzo Airport
- Ave. Duration
- 1h 25m
- When
- Friday to Thursday
- Estimated price
- €35–170
Flights from Trapani Airport to Abruzzo Airport
- Ave. Duration
- 1h 10m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €35–230
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Agrigento Centrale to Termini Imerese
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- Trenitalia
Train from Termini Imerese to Messina Centrale
- Ave. Duration
- 2h 29m
- Frequency
- Hourly
- Estimated price
- €21–30
- Website
- Trenitalia
Train from Napoli Afragola to Isernia
- Ave. Duration
- 1h 49m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Agrigento Bassa to Palermo Centrale
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- €15–22
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Agrigento Centrale to Termini Imerese
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- Trenitalia
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- €15–22
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Agrigento Bassa to Palermo Centrale
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- €15–22
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Agrigento Bassa to Canicatti'
- Ave. Duration
- 40 min
- Frequency
- 5 times a day
- Estimated price
- €4–7
- Website
- Trenitalia
Train from Canicatti' to Comiso
- Ave. Duration
- 1h 36m
- Frequency
- 3 times a day
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Agrigento Piazzale Vittorio Emanuele to Caserta pzza Garibaldi
- Ave. Duration
- 11h 25m
- Frequency
- Once daily
- Estimated price
- €30–45
- Schedules at
- autoservizisalemi.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
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Booking & Getting There
Agrigento to Isernia bus services, operated by Autoservizi Salemi Srl, arrive at Caserta pzza Garibaldi station.
Agrigento to Isernia train services, operated by Trenitalia, arrive at Termini Imerese station.
Book your Agrigento to Isernia train tickets online with Omio.
Book your Agrigento to Isernia bus tickets online with Omio.
There are 458+ hotels available in Isernia.





