Rome2Rio

How to get fromAgen to Sienaby train, plane, train (TGV), bus, car or train (Trenitalia)

Find Transport to Siena

See all options

There are 8 ways to get from Agen to Siena by train, plane, train (TGV), bus, car, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Bordeaux–Mérignac Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Agen to Bordeaux St Jeantrain
    2. Fly from Bordeaux–Mérignac Airport (BOD) to Florence Peretola Airport (FLR)planeBOD - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    9h 2m
    €91–234
  2. Train via Marseille

    cheapest
    1. Take the train from Agen to Marseille St Charlestrain
    2. Take the train from Marseille St Charles to Genova P.Za Principetrain
    3. Take the train from Genova P.Za Principe to Pisa CentraletrainFb / ...
    4. Take the train from Pisa Centrale to EmpolitrainRe
    5. Take the train from Empoli to SienatrainRe
    19h 6m
    €70–376
  3. Train

    1. Take the train from Agen to Toulouse MatabiautrainTer
    2. Take the train from Toulouse Matabiau to Lyon Part DieutrainTgv
    3. Take the train from Lyon Part Dieu to Milano CentraletrainFr
    4. Take the train from Milano Centrale to Florence Santa Maria Novellatrain
    5. Take the train from Firenze S.M.N. to SienatrainRe
    17h 32m
    €128–357
  4. Bus

    1. Take the bus from AGEN - Gare SNCF to AUCH - Gare Routièrebus932
    2. Take the bus from AUCH - Gare Routière to TOULOUSE - Toulousebus935
    3. Take the bus from Toulouse to Florence Villa Constanza Bus Stationbus
    4. Take the bus from Florence Villa Constanza Bus Station to Sienabus443 / ...
    21h 4m
  5. Drive 1,131.7 km

    1. Drive from Agen to Sienacar1,131.7 km
    11h 22m
    €175–253
  6. Train to Toulouse-Blagnac Airport, fly to Florence Peretola Airport, train

    1. Take the train from Agen to Toulouse Matabiautrain
    2. Fly from Toulouse-Blagnac Airport (TLS) to Florence Peretola Airport (FLR)planeTLS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    8h 27m
    €94–257
  7. Train to Bordeaux–Mérignac Airport, fly to Fiumicino International Airport, train

    1. Take the train from Agen to Bordeaux St Jeantrain
    2. Fly from Bordeaux–Mérignac Airport (BOD) to Fiumicino International Airport (FCO)planeBOD - FCO
    3. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    4. Take the train from Firenze S.M.N. to Sienatrain
    11h 32m
    €79–286
  8. Train, bus

    1. Take the train from Agen to Toulouse MatabiautrainTer
    2. Take the bus from Toulouse - Matabiau Bus Station to Perpignan - Bus Stationbus
    3. Take the bus from Perpignan - Bus Station to Florence Villa Constanza Bus Stationbus
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131
    21h 51m

Agen to Siena by train

Calendar14Weekly Trains
Duration17h 32mAverage Duration
Ticket€128Cheapest Price
See schedules

Questions & Answers

What companies run services between Agen, France and Siena, Italy?

You can take a train from Agen to Siena via Toulouse Matabiau, Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 17h 32m. Alternatively, you can take a bus from AGEN - Gare SNCF to Siena via AUCH - Gare Routière, TOULOUSE - Toulouse, Toulouse, and Florence Villa Constanza Bus Station in around 21h 4m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers