Panama travel plans with the routes already figured out
Rome2Rio itineraries for Panama are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.
7 days in Panama
Panama CityTocumenItinerary navigation
Days 1–2: Panama City, Panama
Activities
- El Valle de Anton
- Miraflores Locks Visitors Center
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Fort San Lorenzo
- Fuerte Sherman
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumenbus
- Take the transfer from Colón to Tocumentransfer
- Take the subway from Colón to Tocumensubway
- Take the subway from Colón to Tocumensubway
2h
$5–7
Activities
- Mercado de Mariscos Seafood Market
- Miraflores Locks Visitor Center
Hotel
8 days in Panama
Panama CityDavidItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Gamboa Rainforest Resort Aerial Tram
- Biomuseo
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Zona Libre de Colon
- Paseo Washington
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumenbus
- Take the transfer from Colón to Tocumentransfer
- Take the subway from Colón to Tocumensubway
- Take the subway from Colón to Tocumensubway
2h
$5–7
Activities
- Ancon Hill Viewpoint
- Los Pueblos Shopping Center
Hotel
Day 8: David, Panama
Transport
- Fly from Tocumen to Davidplane
- Take the taxi from Tocumen to Davidtaxi
1h 18m
$72–488
Activities
- Isla Parida Boat Trip
- Playa La Barqueta
Hotel
9 days in Panama
Panama CitySantiagoItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Amador Causeway
- Miraflores Locks Visitors Center
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Cathedral of the Immaculate Conception
- Colon 2000 Cruise Terminal
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumenbus
- Take the transfer from Colón to Tocumentransfer
- Take the subway from Colón to Tocumensubway
- Take the subway from Colón to Tocumensubway
2h
$5–7
Activities
- Amador Causeway
- Cinta Costera Waterfront Promenade
Hotel
Day 8: David, Panama
Transport
- Fly from Tocumen to Davidplane
- Take the taxi from Tocumen to Davidtaxi
1h 18m
$72–488
Activities
- White Water Rafting Chiriqui River
- Catedral de San Jose de David
Hotel
Day 9: Santiago, Panama
Transport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Parque Nacional Santa Fe
- Iglesia San Juan de Dios
Hotel
10 days in Panama
Panama CityPenonoméItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Bridge of the Americas
- National Theatre of Panama
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Fuerte Sherman
- Statue of Christopher Columbus
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumenbus
- Take the transfer from Colón to Tocumentransfer
- Take the subway from Colón to Tocumensubway
- Take the subway from Colón to Tocumensubway
2h
$5–7
Activities
- Miraflores Locks Visitor Center
- Omar Torrijos Herrera Recreational Park
Hotel
Day 8: David, Panama
Transport
- Fly from Tocumen to Davidplane
- Take the taxi from Tocumen to Davidtaxi
1h 18m
$72–488
Activities
- Catedral de San Jose de David
- Coffee Farm Tour Boquete
Hotel
Day 9: Santiago, Panama
Transport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Restaurante El Patio
- Cascada El Salto
Hotel
Day 10: Penonomé, Panama
Transport
- Take the bus from Santiago to Penonomébus
1h 37m
$4–24
Activities
- Local Fonda Dining Experience
- Museo de Penonome
Hotel
