Panama travel plans with the routes already figured out
Rome2Rio itineraries for Panama are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.
7 days in Panama
Panama CityTocumenItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Biomuseo
- Miraflores Locks Visitors Center
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colón
1h 30m
$1
Activities
- Cathedral of the Immaculate Conception
- Zona Libre de Colon
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumen
- Take the transfer from Colón to Tocumen
- Take the subway from Colón to Tocumen
- Take the subway from Colón to Tocumen
2h 15m
$2
Activities
- Omar Torrijos Herrera Recreational Park
- Panama Viejo Historical Site
Hotel
8 days in Panama
Panama CityDavidItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Gamboa Rainforest Resort Aerial Tram
- Miraflores Locks Visitors Center
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colón
1h 30m
$1
Activities
- Gatun Locks Panama Canal
- Portobelo National Park
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumen
- Take the transfer from Colón to Tocumen
- Take the subway from Colón to Tocumen
- Take the subway from Colón to Tocumen
2h 15m
$2
Activities
- Biomuseo
- Omar Torrijos Herrera Recreational Park
Hotel
Day 8: David, Panama
Transport
- Fly from Tocumen to David
- Take the taxi from Tocumen to David
1h 18m
$78–495
Activities
- Mercado Publico de David
- Coffee Farm Tour Boquete
Hotel
9 days in Panama
Panama CitySantiagoItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Church of San Jose
- Gamboa Rainforest Resort Aerial Tram
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colón
1h 30m
$1
Activities
- Cathedral of the Immaculate Conception
- Zona Libre de Colon
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumen
- Take the transfer from Colón to Tocumen
- Take the subway from Colón to Tocumen
- Take the subway from Colón to Tocumen
2h 15m
$2
Activities
- Miraflores Locks Visitor Center
- Summit Municipal Park
Hotel
Day 8: David, Panama
Transport
- Fly from Tocumen to David
- Take the taxi from Tocumen to David
1h 18m
$78–495
Activities
- Explore Boquete Town
- Horseback Riding Boquete Area
Hotel
Day 9: Santiago, Panama
Transport
- Take the bus from David to Santiago
2h 30m
$16–35
Activities
- Mercado Publico de Santiago
- Mirador de Santiago
Hotel
10 days in Panama
Panama CityPenonoméItinerary navigation
Days 1–2: Panama City, Panama
Activities
- Panama Viejo
- Ancon Hill
Hotel
Day 3: Colón, Panama
Transport
- Take the bus from Panama City to Colón
1h 30m
$1
Activities
- Zona Libre de Colon
- Playa Langosta
Hotel
Days 4–7: Tocumen, Panama
Transport
- Take the bus from Colón to Tocumen
- Take the transfer from Colón to Tocumen
- Take the subway from Colón to Tocumen
- Take the subway from Colón to Tocumen
2h 15m
$2
Activities
- Gamboa Rainforest Resort Activities
- Los Pueblos Shopping Center
Hotel
Day 8: David, Panama
Transport
- Fly from Tocumen to David
- Take the taxi from Tocumen to David
1h 18m
$78–495
Activities
- Museo de Historia y Arte Jose de Obaldia
- Horseback Riding Boquete Area
Hotel
Day 9: Santiago, Panama
Transport
- Take the bus from David to Santiago
2h 30m
$16–35
Activities
- Teatro Anayansi
- Mercado Publico de Santiago
Hotel
Day 10: Penonomé, Panama
Transport
- Take the bus from Santiago to Penonomé
2h 2m
$5–25
Activities
- Catedral San Juan Bautista
- Parque Arqueologico El Caño
Hotel
