• Our partners include:

  • RailEurope
  • Deutsche Bahn
  • Trenitalia
  • SNCF
  • Flixbus
  • RENFE
  • Ouibus
  • BlaBlaCar
  • Booking.com
  • Skyscanner

There are 8 ways to get from Prague to Brussels by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Brussels  •  4h 13m

  1. Fly from Prague (PRG) to Brussels (BRU) PRG - BRU

$41 - $203

Cheapest option

Bus  •  14h 10m

  1. Take the bus from Prague, Prague ÚAN Florenc to Brussels, Brussels-North station N84 / ...

$30 - $90

6 alternative options

Fly to Charleroi  •  5h 11m

  1. Fly from Prague (PRG) to Charleroi (CRL) PRG - CRL

$39 - $162

Fly to Amsterdam Schiphol, train  •  6h 5m

  1. Fly from Prague (PRG) to Amsterdam Schiphol (AMS) PRG - AMS
  2. Take the train from Schiphol Airport to Brussel-Zuid/Midi

$107 - $292

Train via Nürnberg Hbf  •  10h 32m

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Köln Messe/Deutz Gl.11-12 Ice
  3. Take the train from Köln Hauptbahnhof to Brusel Nord Ice

$168 - $258

Train  •  13h 25m

  1. Take the train from Praha hl.n. to Dresden Hbf Ec
  2. Take the train from Dresden Hbf to Köln Hbf Ic
  3. Take the train from Köln Hauptbahnhof to Brusel Nord Ice

$194 - $288

Bus via Louvain / Leuven  •  14h 52m

  1. Take the bus from Prague, Prague ÚAN Florenc to Leuven N84

$58 - $94

Drive  •  8h 10m

  1. Drive from Prague to Brussels 561.5 miles

$110 - $170

Questions & Answers

The cheapest way to get from Prague to Brussels is to bus which costs 700 Kč - 2 000 Kč and takes 14h 10m.

More details

The quickest way to get from Prague to Brussels is to fly which costs 900 Kč - 4 600 Kč and takes 4h 13m.

More details

Yes, there is a direct bus departing from Prague, Prague ÚAN Florenc and arriving at Brussels, Brussels-North station station. Services depart twice daily, and operate every day. The journey takes approximately 14h 10m.

More details

No, there is no direct train from Prague to Brussels. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Brusel Nord via Nürnberg Hbf, Köln, Deutz Bf Deutz / Messe LANXESS arena and Köln Hauptbahnhof. The journey, including transfers, takes approximately 10h 32m.

More details

The distance between Prague and Brussels is 717 km. The road distance is 898.3 km.

Get driving directions

The best way to get from Prague to Brussels without a car is to train which takes 10h 32m and costs 3 700 Kč - 6 000 Kč.

More details

It takes approximately 4h 13m to get from Prague to Brussels, including transfers.

More details

Prague to Brussels bus services, operated by FlixBus, depart from Prague, Prague ÚAN Florenc station.

More details

Prague to Brussels train services, operated by Czech Railways (ČD), depart from Praha hl.n. (Autobusová St. Wilsonova) station.

More details

The best way to get from Prague to Brussels is to fly which takes 4h 13m and costs 900 Kč - 4 600 Kč. Alternatively, you can train, which costs 3 700 Kč - 6 000 Kč and takes 10h 32m, you could also bus, which costs 700 Kč - 2 000 Kč and takes 14h 10m.

Mode details

Map of how to get from Prague to Brussels.
Launch map view
  • Distance: 448.3 miles
  • Duration: 4h 13m

What companies run services between Prague, Czech Republic and Brussels, Belgium?

Brussels Airlines, CSA and three other airlines fly from Prague to Brussels every 3 hours. Alternatively, you can take a train from Prague to Brussels via Nürnberg ZOB, Nürnberg Hbf, Köln Messe/Deutz Gl.11-12, Köln, Deutz Bf Deutz / Messe LANXESS arena, and Köln Hauptbahnhof in around 10h 32m.

Airlines
CSA
Website
csa.cz
Flights from Prague to Brussels
Ave. Duration
1h 30m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$35 - $310
Flights from Prague to Amsterdam Schiphol
Ave. Duration
1h 38m
When
Every day
Estimated price
$100 - $440
KLM
Website
klm.com
Flights from Prague to Brussels via Amsterdam Schiphol
Ave. Duration
3h
When
Every day
Estimated price
$150 - $600
Flights from Prague to Amsterdam Schiphol
Ave. Duration
1h 38m
When
Every day
Estimated price
$110 - $450
Lufthansa
Website
lufthansa.com
Flights from Prague to Brussels via Munich
Ave. Duration
3h 17m
When
Every day
Estimated price
$160 - $850
Flights from Prague to Brussels via Frankfurt
Ave. Duration
3h 35m
When
Every day
Estimated price
$160 - $850
Flights from Prague to Amsterdam Schiphol via Frankfurt
Ave. Duration
3h 45m
When
Every day
Estimated price
$180 - $800
Brussels Airlines
Website
brusselsairlines.com
Flights from Prague to Brussels
Ave. Duration
1h 30m
When
Every day
Estimated price
$50 - $390
Austrian Airlines
Website
austrian.com
Flights from Prague to Brussels via Vienna
Ave. Duration
3h 50m
When
Monday, Wednesday, Thursday and Friday
Estimated price
$160 - $850
Flights from Prague to Amsterdam Schiphol via Vienna
Ave. Duration
3h 50m
When
Monday, Wednesday, Thursday and Friday
Estimated price
$190 - $850
Ryanair
Website
ryanair.com
Flights from Prague to Charleroi
Ave. Duration
1h 30m
When
Every day
Estimated price
$21 - $200
easyJet
Website
easyjet.com
Flights from Prague to Amsterdam Schiphol
Ave. Duration
1h 40m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$55 - $280
Norwegian Air International
Website
norwegian.com
Flights from Prague to Amsterdam Schiphol via Copenhagen
Ave. Duration
3h 55m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$60 - $360
Train operators
Thalys
Phone
+32 70 66 77 88
Website
thalys.com
Train from Schiphol Airport to Brussel-Zuid/Midi
Ave. Duration
1h 34m
Frequency
Hourly
Estimated price
$55 - $80
Website
thalys.com
2nd Class
$55 - $80
1st Class
$80 - $110
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3h 35m
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
cd.cz
Train from Praha hl.n. to Dresden Hbf
Ave. Duration
2h 17m
Frequency
Every 3 hours
Estimated price
$19 - $28
Website
cd.cz
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Nürnberg Hbf to Köln Messe/Deutz Gl.11-12
Ave. Duration
3h 14m
Frequency
Hourly
Estimated price
$80 - $120
Website
bahn.de
Train from Köln Hauptbahnhof to Brusel Nord
Ave. Duration
1h 43m
Frequency
Every 4 hours
Estimated price
$45 - $70
Website
bahn.de
Train from Dresden Hbf to Köln Hbf
Ave. Duration
7h 25m
Frequency
Every 3 hours
Estimated price
$130 - $190
Website
bahn.de
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Prague, Prague ÚAN Florenc to Brussels, Brussels-North station
Ave. Duration
14h 10m
Frequency
Twice daily
Estimated price
$50 - $90
Website
flixbus.co.uk
Bus from Prague, Prague ÚAN Florenc to Leuven
Ave. Duration
14h
Frequency
4 times a week
Estimated price
$50 - $90
Website
flixbus.co.uk
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Prague, ÚAN Florenc to Brussels, Gare du Midi
Ave. Duration
12h
Frequency
Once daily
Estimated price
$30 - $40
Website
regiojet.com
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Brussels
Ave. Duration
13h 30m
Frequency
6 times a week
Estimated price
$50 - $90
Schedules at
elines.cz

Want to know more about travelling around Belgium

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Prague Airport to Brussels Airport is the direct flight which takes 1h 25m.

Search flights

Prague to Brussels bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

More details

Prague to Brussels train services, operated by Deutsche Bahn, arrive at Brusel Nord station.

More details

Yes, the driving distance between Prague to Brussels is 898 km. It takes approximately 8h 10m to drive from Prague to Brussels.

Get driving directions

CSA, KLM, Austrian Airlines and two other airlines offer flights from Prague Airport to Brussels Airport.

Search flights

Book your Prague to Brussels train tickets online with Rome2rio.

Search and book

Book your Prague to Brussels bus tickets online with FlixBus and Distribusion.

Search and book

There are 1016+ hotels available in Brussels. Prices start at $69 USD per night.

More details